{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T03:59:06Z","timestamp":1763006346568,"version":"3.45.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005739","name":"National Autonomous University of Mexico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005739","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Inflammatory myofibroblastic tumor (IMT), historically misclassified as inflammatory pseudotumor, is a rare, intermediate-grade neoplasm with low metastatic potential and a high recurrence rate. It primarily affects the lungs, with colorectal involvement being exceptionally uncommon. We present the case of a 32-year-old woman initially diagnosed with Stage III pelvic inflammatory disease, whose surgical exploration revealed an abscessed ileocecal mass. A right hemicolectomy was successfully performed, and histopathological examination confirmed an anaplastic lymphoma kinase (ALK)-negative IMT. The diagnosis is challenging due to the nonspecific nature of clinical and radiologic findings and significant histologic overlap with other spindle cell tumors. Immunohistochemistry and molecular profiling are essential for accurate classification, particularly in ALK-negative cases. Surgical resection remains the mainstay of treatment. This case highlights the importance of including IMT in the differential diagnosis of atypical intra-abdominal masses and supports the role of advanced molecular techniques in improving diagnostic accuracy and management.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf902","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T03:57:22Z","timestamp":1763006242000},"source":"Crossref","is-referenced-by-count":0,"title":["Anaplastic lymphoma kinase-negative inflammatory myofibroblastic tumor of the appendix and ileocecal region: a rare clinical entity"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9785-9300","authenticated-orcid":false,"given":"Mar\u00eda Guadalupe","family":"S\u00e1nchez-Villegas","sequence":"first","affiliation":[{"name":"Faculty of Medicine, National Autonomous University of Mexico (UNAM), Escolar 411A, Copilco Universidad , Coyoac\u00e1n, 04360 Mexico City ,","place":["Mexico"]},{"name":"Department of General and Endoscopic Surgery, Dr. Manuel Gea Gonz\u00e1lez General Hospital , Calzada de Tlalpan 4800, Belisario Dom\u00ednguez Section XVI, Tlalpan, 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica Jazm\u00edn","family":"Betancourt-Ferreyra","sequence":"additional","affiliation":[{"name":"Department of General and Endoscopic Surgery, Dr. Manuel Gea Gonz\u00e1lez General Hospital , Calzada de Tlalpan 4800, Belisario Dom\u00ednguez Section XVI, Tlalpan, 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Alberto","family":"Ortiz-Dumas","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, National Autonomous University of Mexico (UNAM), Escolar 411A, Copilco Universidad , Coyoac\u00e1n, 04360 Mexico City ,","place":["Mexico"]},{"name":"Department of Pathological Anatomy, Dr. Manuel Gea Gonz\u00e1lez General Hospital , Calzada de Tlalpan 4800, Belisario Dom\u00ednguez Section XVI, Tlalpan, 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Gerardo","family":"Fr\u00edas-M\u00e9ndez","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Therapeutic Imaging, Dr. Manuel Gea Gonz\u00e1lez General Hospital , Calzada de Tlalpan 4800, Belisario Dom\u00ednguez Section XVI, Tlalpan, 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda del Roc\u00edo","family":"Estrada-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy, Dr. Manuel Gea Gonz\u00e1lez General Hospital , Calzada de Tlalpan 4800, Belisario Dom\u00ednguez Section XVI, Tlalpan, 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9249-3321","authenticated-orcid":false,"given":"Mario Eduardo","family":"Trejo-\u00c1vila","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, National Autonomous University of Mexico (UNAM), Escolar 411A, Copilco Universidad , Coyoac\u00e1n, 04360 Mexico City ,","place":["Mexico"]},{"name":"Department of General and Endoscopic Surgery, Dr. Manuel Gea Gonz\u00e1lez General Hospital , Calzada de Tlalpan 4800, Belisario Dom\u00ednguez Section XVI, Tlalpan, 14080 Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,11,13]]},"reference":[{"key":"2025111222571523200_ref1","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.advms.2022.02.002","article-title":"What do we know about inflammatory myofibroblastic tumors?\u2014a systematic review","volume":"67","author":"Siemion","year":"2022","journal-title":"Adv Med 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