{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T15:26:11Z","timestamp":1778858771074,"version":"3.51.4"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Fournier\u2019s gangrene is a necrotizing fasciitis of the perineum that can occur due to a loss of integrity of the gastrointestinal or urethral mucosa. Its appearance as the debut of a perforated rectal neoplasm is unusual, more uncommon in young patients, leading to an advanced stage of the disease. Therefore, we present the case of a 47-year-old male with Fournier\u2019s gangrene as the debut of a rectal cancer that, despite severe presentation, the pathological stage was early (pT2N0), highlighting the importance of considering neoplastic etiology in perineal gangrene and the need for an early multidisciplinary approach.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf915","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T23:22:52Z","timestamp":1763076172000},"source":"Crossref","is-referenced-by-count":1,"title":["Fournier\u2019s gangrene as initial presentation of rectal cancer"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9215-6801","authenticated-orcid":false,"given":"Sa\u00fal","family":"S\u00e1nchez Iglesias","sequence":"first","affiliation":[{"name":"Hospital Universitario de Toledo , Avenida del Rio Guadina, Toledo 45007 ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"de la Cruz Cuadrado","sequence":"additional","affiliation":[{"name":"Hospital Universitario de Toledo , Avenida del Rio Guadina, Toledo 45007 ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juli\u00e1n","family":"de Pedro Conal","sequence":"additional","affiliation":[{"name":"Hospital Universitario de Toledo , Avenida del Rio Guadina, Toledo 45007 ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,11,13]]},"reference":[{"key":"2025111318224701800_ref1","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1046\/j.1365-2168.2000.01497.x","article-title":"Fournier's gangrene: a review of 1726 cases","volume":"87","author":"Eke","year":"2000","journal-title":"Br J Surg"},{"key":"2025111318224701800_ref2","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/1749-7922-8-13","article-title":"Fournier's gangrene: our experience with 50 patients and analysis of factors affecting mortality","volume":"8","author":"Benjelloun el","year":"2013","journal-title":"World J Emerg Surg"},{"key":"2025111318224701800_ref3","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1186\/s12957-016-0989-z","article-title":"Severe Fournier's gangrene in a patient with rectal cancer: case report and literature review","volume":"14","author":"Yoshino","year":"2016","journal-title":"World J Surg Oncol"},{"key":"2025111318224701800_ref4","doi-asserted-by":"crossref","first-page":"E184","DOI":"10.1177\/000313481508100418","article-title":"Oncologic management dilemma of locally advanced occult rectal cancer presenting as Fournier's gangrene","volume":"81","author":"Hamidian Jahromi","year":"2015","journal-title":"Am Surg"},{"key":"2025111318224701800_ref5","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1007\/BF02052594","article-title":"Perineal wound management after abdominoperineal rectal excision for carcinoma with unsatisfactory hemostasis or gross septic contamination: primary closure vs. packing. A multicenter, controlled trial. French Association for Surgical Research","volume":"37","author":"Delalande","year":"1994","journal-title":"Dis Colon Rectum"},{"key":"2025111318224701800_ref6","doi-asserted-by":"publisher","first-page":"20499361241238521","DOI":"10.1177\/20499361241238521","article-title":"Fournier's gangrene: a review of predictive scoring systems and practical guide for patient management","volume":"11","author":"Bowen","year":"2024","journal-title":"Ther Adv Infect Dis"},{"key":"2025111318224701800_ref7","doi-asserted-by":"publisher","first-page":"e605","DOI":"10.1200\/JCO.2010.29.5394","article-title":"Perforated rectal cancer presenting as Fournier's gangrene","volume":"28","author":"Carr","year":"2010","journal-title":"J Clin Oncol"},{"key":"2025111318224701800_ref8","doi-asserted-by":"publisher","first-page":"288","DOI":"10.11604\/pamj.2015.20.288.5506","article-title":"Fournier gangrene: rare complication of rectal cancer","volume":"20","author":"Ossibi","year":"2015","journal-title":"Pan Afr Med J"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/11\/rjaf915\/65286170\/rjaf915.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/11\/rjaf915\/65286170\/rjaf915.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T23:22:53Z","timestamp":1763076173000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf915\/8322607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,1]]},"references-count":8,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf915","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,11]]},"published":{"date-parts":[[2025,11,1]]},"article-number":"rjaf915"}}