{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T13:51:24Z","timestamp":1765633884575,"version":"3.48.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Kidney transplantation in individuals with congenital skin fragility diseases is exceedingly uncommon due to perioperative concerns such as compromised wound healing, respiratory complications, and issues with vascular access. Herein, we report a case of successful living-donor kidney transplantation in a 37-year-old male with dystrophic epidermolysis bullosa and end-stage renal disease. Multidisciplinary planning, customized anesthesia, and protective intraoperative measures are essential to avoid these problems. Epidural anesthesia combined with mild sedation facilitated surgery without the need for airway instrumentation, while meticulous handling maintained skin integrity. The operation and recovery were unremarkable, and the graft function was maintained at 12\u00a0months. This case demonstrates that complex transplantation is achievable in environments with limited resources, through personalized perioperative treatment and interdisciplinary cooperation.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf984","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T12:34:17Z","timestamp":1763987657000},"source":"Crossref","is-referenced-by-count":0,"title":["Living donor kidney transplantation in a patient with inherited skin fragility disorder in a resource-limited setting: a case report"],"prefix":"10.1093","volume":"2025","author":[{"given":"Sasho","family":"Dohchev","sequence":"first","affiliation":[{"name":"University Clinic for Urology Faculty of Medicine, Ss. Cyril and Methodius University , Majka Tereza 17, 1000 Skopje, RN \u00a0","place":["Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandar","family":"Trifunovski","sequence":"additional","affiliation":[{"name":"University Clinic for Urology Faculty of Medicine, Ss. Cyril and Methodius University , Majka Tereza 17, 1000 Skopje, RN \u00a0","place":["Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitar","family":"Trajkovski","sequence":"additional","affiliation":[{"name":"University Clinic for Urology Faculty of Medicine, Ss. Cyril and Methodius University , Majka Tereza 17, 1000 Skopje, RN \u00a0","place":["Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josif","family":"Janchulev","sequence":"additional","affiliation":[{"name":"University Clinic for Urology Faculty of Medicine, Ss. Cyril and Methodius University , Majka Tereza 17, 1000 Skopje, RN \u00a0","place":["Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9593-2502","authenticated-orcid":false,"given":"Aleksandra Gavrilovska","family":"Brzanov","sequence":"additional","affiliation":[{"name":"Department for Anesthesia, Reanimation, and Intensive Care, University Clinic for Traumatology Orthopedic Disease, Faculty of Medicine, Ss. Cyril and Methodius University , Majka Tereza 17, 1000 Skopje, RN \u00a0","place":["Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaklina Shterjova","family":"Markovska","sequence":"additional","affiliation":[{"name":"University Clinic for Nephrology Faculty of Medicine, Ss. Cyril and Methodius University , Majka Tereza 17, 1000 Skopje, RN \u00a0","place":["Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana Dohcheva","family":"Karajovanov","sequence":"additional","affiliation":[{"name":"University Clinic for Dermatology Faculty of Medicine, Ss. Cyril and Methodius University , Majka Tereza 17, 1000 Skopje, RN \u00a0","place":["Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irena Rambabova","family":"Bushljetik","sequence":"additional","affiliation":[{"name":"University Clinic for Nephrology Faculty of Medicine, Ss. Cyril and Methodius University , Majka Tereza 17, 1000 Skopje, RN \u00a0","place":["Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5628-2500","authenticated-orcid":false,"given":"Goce","family":"Spasovski","sequence":"additional","affiliation":[{"name":"University Clinic for Nephrology Faculty of Medicine, Ss. Cyril and Methodius University , Majka Tereza 17, 1000 Skopje, RN \u00a0","place":["Macedonia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,12,13]]},"reference":[{"key":"2025121308500673900_ref1","doi-asserted-by":"publisher","first-page":"5","DOI":"10.6002\/ect.DonorSymp.2022.L12","article-title":"Living kidney donor transplantation and global kidney exchange","volume":"20","author":"Marino","year":"2022","journal-title":"Exp Clin Transplant"},{"key":"2025121308500673900_ref2","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1016\/j.jaad.2008.02.004","article-title":"The classification of inherited epidermolysis bullosa (EB): report of the third international consensus meeting on diagnosis and classification of EB","volume":"58","author":"Fine","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"2025121308500673900_ref3","first-page":"649","volume-title":"Fitzpatrick\u2019s Dermatology in General Medicine","author":"Marinkovich","year":"2012","edition":"8th"},{"key":"2025121308500673900_ref4","doi-asserted-by":"publisher","first-page":"5","DOI":"10.6002\/ect.DonorSymp.2022.L12","article-title":"Living kidney donor transplantation and global kidney exchange","volume":"20","author":"Marino","year":"2022","journal-title":"Exp Clin Transplant"},{"key":"2025121308500673900_ref5","doi-asserted-by":"publisher","first-page":"3074","DOI":"10.1016\/j.transproceed.2019.04.049","article-title":"Living donor kidney transplantation in a patient with epidermolysis bullosa: a case report","volume":"51","author":"Ceuppens","year":"2019","journal-title":"Transplant Proc"},{"key":"2025121308500673900_ref6","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1111\/ced.12300","article-title":"Successful renal transplant in a patient with non-Herlitz junctional epidermolysis bullosa","volume":"39","author":"Ungureanu","year":"2014","journal-title":"Clin Exp Dermatol"},{"key":"2025121308500673900_ref7","doi-asserted-by":"publisher","first-page":"46","DOI":"10.31053\/1853.0605.v75.n1.17153","article-title":"Reporte de Caso: Trasplante renal en un paciente con Epidermolisis bullosa [Renal transplantation in a patient with recessive dystrophic epidermolysis bullosa: a case report]","volume":"75","author":"Saad","year":"2018","journal-title":"Rev Fac Cien Med Univ Nac Cordoba"},{"key":"2025121308500673900_ref8","doi-asserted-by":"publisher","first-page":"e14489","DOI":"10.1111\/dth.14489","article-title":"Successful use of cyclosporine in epidermolysis bullosa pruriginosa","volume":"33","author":"Kaushik","year":"2020","journal-title":"Dermatol Ther"},{"key":"2025121308500673900_ref9","doi-asserted-by":"publisher","first-page":"12446","DOI":"10.3390\/ijms222212446","article-title":"Keratins as an inflammation trigger point in epidermolysis bullosa simplex","volume":"22","author":"Evtushenko","year":"2021","journal-title":"Int J Mol Sci"},{"key":"2025121308500673900_ref10","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1093\/jscr\/rjaa310","article-title":"Anastomosis of dual renal transplant veins","volume":"9","author":"Hoff","year":"2020","journal-title":"Journal of Surgical Case Reports"},{"key":"2025121308500673900_ref11","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1213\/ANE.0000000000005706","article-title":"Anesthetic management of adults with epidermolysis bullosa","volume":"134","author":"Mittal","year":"2022","journal-title":"Anesth Analg"},{"key":"2025121308500673900_ref12","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/bs.mie.2015.09.032","article-title":"Skin keratins","volume":"568","author":"Wang","year":"2016","journal-title":"Methods Enzymol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/12\/rjaf984\/65877076\/rjaf984.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/12\/rjaf984\/65877076\/rjaf984.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T13:50:13Z","timestamp":1765633813000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf984\/8379493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,29]]},"references-count":12,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,11,29]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf984","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,12]]},"published":{"date-parts":[[2025,11,29]]},"article-number":"rjaf984"}}