{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T17:25:12Z","timestamp":1766078712379,"version":"3.48.0"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Mixed neuroendocrine\u2013non-neuroendocrine neoplasms (MiNENs) of the rectum are extremely rare and pose significant diagnostic challenges. We report a 69-year-old man with rectal MiNEN successfully treated with a robot-assisted Hartmann\u2019s procedure. Preoperative contrast-enhanced CT revealed a vascular stalk-like structure within the tumor. Gross pathology showed a clear demarcation between adenocarcinoma and small-cell neuroendocrine carcinoma. Robot-assisted surgery facilitated precise dissection in the narrow pelvic cavity and safe distal transection through a transanal approach. This case highlights unique radiological and pathological findings that may aid in the diagnosis and management of rectal MiNEN.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf996","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T12:53:49Z","timestamp":1764680029000},"source":"Crossref","is-referenced-by-count":0,"title":["A case of rectal MiNEN demonstrating vascular stalk-like imaging and gross demarcation of tumor components"],"prefix":"10.1093","volume":"2025","author":[{"given":"Masato","family":"Hayashi","sequence":"first","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Kotake","sequence":"additional","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Kitabayashi","sequence":"additional","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuki","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Fujimori","sequence":"additional","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichiro","family":"Sawada","sequence":"additional","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironori","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaeko","family":"Oyama","sequence":"additional","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuo","family":"Hara","sequence":"additional","affiliation":[{"name":"Department of Surgery , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichiro","family":"Tsukada","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munenori","family":"Mukai","sequence":"additional","affiliation":[{"name":"Department of Pathology , Koseiren Takaoka Hospital, Eirakumachi 5-10, Takaoka, Toyama 933-8555,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"Inaki","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, Breast Surgery, Kanazawa University Graduate School of Medical Sciences , 13-1 Takaramachi, Kanazawa , Ishikawa 920-8640,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,12,18]]},"reference":[{"key":"2025121812190460800_ref1","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1111\/his.13975","article-title":"The 2019 WHO classification of tumours of the digestive system","volume":"76","author":"Nagtegaal","year":"2020","journal-title":"Histopathology"},{"key":"2025121812190460800_ref2","doi-asserted-by":"publisher","first-page":"273","DOI":"10.3390\/jcm9010273","article-title":"Mixed neuroendocrine non-neuroendocrine neoplasms: a systematic review of a controversial and underestimated diagnosis","volume":"9","author":"Frizziero","year":"2020","journal-title":"J Clin Med"},{"key":"2025121812190460800_ref3","doi-asserted-by":"publisher","first-page":"1007317","DOI":"10.3389\/fonc.2022.1007317","article-title":"Comprehensive analysis of mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs): a SEER 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