{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T05:22:05Z","timestamp":1770096125580,"version":"3.49.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department of Pathology and Laboratory Medicine at the University of Arizona"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Meckel\u2019s diverticulum (MD) is a common developmental abnormality of the gastrointestinal tract that, in adults, is usually asymptomatic but can present with complications including malignancy. Although malignancy in MD is rare overall, MD is recognized a high-risk site for tumorigenesis compared to the surrounding ileum. Neuroendocrine neoplasms are the most common malignancy arising in MD and are often associated with nodal metastases, even if the primary tumor is small. We report the case of a 66-year-old male who underwent exploratory laparotomy for small bowel obstruction and was intraoperatively found to have MD causing an internal hernia. Pathologic examination of the diverticulectomy specimen revealed a well-differentiated neuroendocrine tumor, grade 1, pathologic stage pT2. The case highlights the role of resection for incidentally found and symptomatic MD due to the elevated risk of malignancy at this site.<\/jats:p>","DOI":"10.1093\/jscr\/rjag025","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T12:39:05Z","timestamp":1768999145000},"source":"Crossref","is-referenced-by-count":0,"title":["Neuroendocrine tumor arising in Meckel\u2019s diverticulum presenting with bowel obstruction"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2011-7789","authenticated-orcid":false,"given":"Jillian C","family":"Dawley","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Banner - University Medical Center, University of Arizona , 1625 N Campbell Ave, Tucson, AZ 85719 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James H","family":"McClenathan","sequence":"additional","affiliation":[{"name":"Department of Surgery, Banner - University Medical Center, University of Arizona , 1625 N Campbell Ave, Tucson, AZ 85719 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0055-2206","authenticated-orcid":false,"given":"Belinda L","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Banner - University Medical Center, University of Arizona , 1625 N Campbell Ave, Tucson, AZ 85719 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"2026013008451852100_ref1","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1177\/2050640617752771","article-title":"Malignancy and Meckel's diverticulum: a systematic literature review and 14-year experience at a tertiary referral center","volume":"6","author":"Van Malderen","year":"2018","journal-title":"United European Gastroenterol J"},{"key":"2026013008451852100_ref2","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1097\/SLA.0b013e3181ef488d","article-title":"Meckel's diverticulum--a high-risk region for malignancy in the ileum. Insights from a population-based epidemiological study and implications in surgical management","volume":"253","author":"Thirunavukarasu","year":"2011","journal-title":"Ann Surg"},{"key":"2026013008451852100_ref3","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1007\/s11605-018-04096-7","article-title":"Neuroendocrine tumors in Meckel's diverticulum: recommendation for lymphadenectomy regardless of tumor size based on the NCDB experience","volume":"23","author":"Dogeas","year":"2019","journal-title":"J Gastrointest Surg"},{"key":"2026013008451852100_ref4","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s40792-024-01821-0","article-title":"Simultaneous resection of a neuroendocrine tumor in an incidental Meckel's diverticulum with transabdominal preperitoneal hernial repair: a case report","volume":"10","author":"Kato","year":"2024","journal-title":"Surg Case Rep"},{"key":"2026013008451852100_ref5","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.jviscsurg.2017.06.006","article-title":"Meckel's diverticulum in the adult","volume":"154","author":"Lequet","year":"2017","journal-title":"J Visc Surg"},{"key":"2026013008451852100_ref6","doi-asserted-by":"publisher","first-page":"e01345","DOI":"10.14309\/crj.0000000000001345","article-title":"Unusual upper gastrointestinal bleeding due to a neuroendocrine tumor arising in Meckel diverticulum","volume":"11","author":"Eberly","year":"2024","journal-title":"ACG Case Rep J"},{"key":"2026013008451852100_ref7","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1007\/s11605-013-2191-8","article-title":"Neuroendocrine tumors arising in Meckel's diverticula: frequency of advanced disease warrants aggressive management","volume":"17","author":"Lorenzen","year":"2013","journal-title":"J Gastrointest Surg"},{"key":"2026013008451852100_ref8","doi-asserted-by":"crossref","first-page":"251","DOI":"10.33160\/yam.2017.12.007","article-title":"Neuroendocrine tumor arising from Meckel's diverticulum unexpectedly diagnosed after diverticulectomy and in which multiple lymph node metastases were found after reoperation: a case report","volume":"60","author":"Sugezawa","year":"2018","journal-title":"Yonago Acta Med"},{"key":"2026013008451852100_ref9","first-page":"1861","article-title":"Incidental finding of a neuroendocrine tumor arising from Meckel diverticulum during hernia repair: a case report and literature review","volume":"36","author":"Bacalbasa","year":"2016","journal-title":"Anticancer Res"},{"key":"2026013008451852100_ref10","doi-asserted-by":"publisher","first-page":"rjaf085","DOI":"10.1093\/jscr\/rjaf085","article-title":"Recurrent intussusception in a child revealing a neuroendocrine tumor within a Meckel's diverticulum: a case report","volume":"2025","author":"Naji","year":"2025","journal-title":"J Surg Case Rep"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/1\/rjag025\/66641034\/rjag025.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/1\/rjag025\/66641034\/rjag025.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T13:45:23Z","timestamp":1769780723000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag025\/8445449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,24]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12,24]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag025","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1]]},"published":{"date-parts":[[2025,12,24]]},"article-number":"rjag025"}}