{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T14:30:08Z","timestamp":1792420208194,"version":"4.5.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Acute appendicitis is the most frequent non-obstetrical surgical emergency during pregnancy. Anatomical displacement of the appendix and atypical symptoms complicate diagnosis, often delaying treatment and increasing maternal\u2013fetal risks. A retrospective study of seven pregnant women treated for acute appendicitis at National Maternal and Child Health Center between 01 January 2023 and 31 December 2024. Epidemiological, clinical, diagnostic, therapeutic, and outcome data were analyzed using descriptive and inferential statistics. Mean age was 31\u00a0years (SD 7.2; range 21\u201342). Most cases occurred in the third trimester (57%). Four cases were recorded in 2023 and three in 2024. Farmers represented 57% of patients, workers 29%, and housewives 14%. Geographically, cases originated from six provinces, with Tboung Khmum contributing the highest number (29%). Consultation delay was longer in complicated appendicitis (mean 5.2 vs. 2.3\u00a0days, P\u2009&amp;lt;\u2009.05). Elevated C-Reactive Protein (CRP) (&amp;gt;50\u00a0mg\/L) was significantly associated with advanced forms (\u03c72\u2009=\u20094.9, P\u2009=\u2009.027). Ultrasound confirmed appendicitis in 86% of cases, with atypical localization more frequent in the third trimester (P\u2009&amp;lt;\u2009.05). All patients underwent open surgery: McBurney (1 case), para-median (1 case), or modified McBurney (5 cases). Antibiotic regimens were tailored to severity. No maternal deaths occurred; one fetal death with premature delivery at 31\u00a0weeks was noted. Inferential analysis confirms that delayed consultation and elevated CRP are predictors of complicated appendicitis in pregnancy. Systematic ultrasonography and rapid intervention are essential to reduce morbidity.<\/jats:p>","DOI":"10.1093\/jscr\/rjag037","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T12:32:56Z","timestamp":1768307576000},"source":"Crossref","is-referenced-by-count":1,"title":["Acute appendicitis during pregnancy: a retrospective case series of seven cases"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2198-4836","authenticated-orcid":false,"given":"Chansokha","family":"Soeur","sequence":"first","affiliation":[{"name":"General Surgery Department, National Maternal and Child Health Center , 31A, Street 47 (France Street), Srah Chak Sangkat, Doun Penh Khan, Phnom Penh 120408 ,","place":["Cambodia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,2,6]]},"reference":[{"key":"2026020611574398100_ref1","first-page":"444","article-title":"Intra-abdominal surgery during pregnancy","volume":"157","author":"Allen","year":"1989","journal-title":"Am J Surg"},{"key":"2026020611574398100_ref2","first-page":"145","article-title":"Appendicite aigu\u00eb au troisi\u00e8me trimestre de la grossesse","volume":"92","author":"Berthet-Badetti","year":"1997","journal-title":"Rev Fr Gynecol Obstet"},{"key":"2026020611574398100_ref3","first-page":"102","article-title":"Appendicite aigu\u00eb chez la femme enceinte: \u00e0 propos de 18 cas","volume":"94","author":"Nouira","year":"1999","journal-title":"Rev Fr Gynecol Obstet"},{"key":"2026020611574398100_ref6","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1001\/archsurg.1985.01390360028007","article-title":"Acute appendicitis during pregnancy","volume":"120","author":"Horowitz","year":"1985","journal-title":"Arch Surg"},{"key":"2026020611574398100_ref7","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1034\/j.1600-0412.1999.780903.x","article-title":"Appendicitis in pregnancy: diagnosis, management and complications","volume":"78","author":"Andersen","year":"1999","journal-title":"Acta Obstet Gynecol Scand"},{"key":"2026020611574398100_ref9","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/S0368-2315(05)82885-6","article-title":"Appendicite aigu\u00eb et grossesse: \u00e0 propos de 21 cas","volume":"34","author":"Lebeau","year":"2005","journal-title":"J Gynecol Obstet Biol Reprod"},{"key":"2026020611574398100_ref10","first-page":"1877","article-title":"Appendicite aigu\u00eb Sur grossesse: aspects \u00e9pid\u00e9miologiques et diagnostiques","volume":"15","author":"Sanou","year":"2015","journal-title":"J Afr Chir Dig"},{"key":"2026020611574398100_ref4","first-page":"89","article-title":"L\u2019appendicite aigu\u00eb au cours de la gravido-puerp\u00e9ralit\u00e9","volume":"10","author":"Leroy","year":"1981","journal-title":"Med Chir Dig"},{"key":"2026020611574398100_ref5","first-page":"201","article-title":"Appendicite et grossesse: les conditions du succ\u00e8s","volume":"12","author":"Touhami","year":"1984","journal-title":"Maghreb M\u00e9dical"},{"key":"2026020611574398100_ref8","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1148\/radiology.215.2.r00ma24337","article-title":"Appendicitis at the millennium","volume":"215","author":"Birnbaum","year":"2000","journal-title":"Radiology."}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/2\/rjag037\/66800038\/rjag037.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/2\/rjag037\/66800038\/rjag037.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T16:57:50Z","timestamp":1770397070000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag037\/8466485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,31]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,1,31]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag037","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,2]]},"published":{"date-parts":[[2026,1,31]]},"article-number":"rjag037"}}