{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T18:29:55Z","timestamp":1771525795232,"version":"3.50.1"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Appendiceal neoplasms (AN) are an uncommon condition that are typically diagnosed incidentally following an appendicectomy for appendicitis. However, there has been an increased incidence of AN, thought to be secondary to the increased use of computer tomography scans. Therefore, understanding of a broad range of differentials and management of potential AN is necessary for general surgeons.<\/jats:p>\n                  <jats:p>This case report describes an exceptionally rare occurrence of three distinct neoplastic processes\u2014mixed neuroendocrine tumor, goblet cell adenocarcinoma, and low-grade appendiceal mucinous neoplasm\u2014coexisting within a single appendix. We believe this case provides valuable clinical and pathological insights into the broad range of AN, highlighting the diagnostic challenges and the role of the multidisciplinary team.<\/jats:p>","DOI":"10.1093\/jscr\/rjag077","type":"journal-article","created":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T12:44:44Z","timestamp":1769604284000},"source":"Crossref","is-referenced-by-count":0,"title":["Three in one: a case report of mixed neuroendocrine tumor, goblet cell adenocarcinoma and low-grade mucinous neoplasm in a single appendix"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2300-826X","authenticated-orcid":false,"given":"Vivian","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Liverpool Hospital , Sydney, NSW 2170 ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tristan","family":"Rutland","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology, Liverpool Hospital , Sydney, NSW 2170 ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Gibson","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Liverpool Hospital , Sydney, NSW 2170 ,","place":["Australia"]},{"name":"Department of Surgery, Faculty of Medicine, The University of New South Wales , Sydney, NSW 2170 ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahtab","family":"Farzin","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology, Liverpool Hospital , Sydney, NSW 2170 ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,2,19]]},"reference":[{"key":"2026021912532741700_ref1","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1055\/s-0038-1642051","article-title":"Appendiceal neoplasms","volume":"31","author":"Hatch","year":"2018","journal-title":"Clin Colon Rectal Surg"},{"key":"2026021912532741700_ref2","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1097\/PAS.0b013e3181e52916","article-title":"Combined classical carcinoid and goblet cell carcinoid tumor: a new morphologic variant of carcinoid tumor of the appendix","volume":"34","author":"Chetty","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"2026021912532741700_ref3","doi-asserted-by":"publisher","first-page":"e0294153","DOI":"10.1371\/journal.pone.0294153","article-title":"Incidence trends and survival analysis of appendiceal tumors in the United States: primarily changes in appendiceal neuroendocrine tumors","volume":"18","author":"Wang","year":"2023","journal-title":"PloS One"},{"key":"2026021912532741700_ref4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1080\/17474124.2021.1832467","article-title":"Appendiceal neoplasm incidence and mortality rates are on the rise in Australia","volume":"15","author":"Mikaeel","year":"2021","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"2026021912532741700_ref5","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3390\/cancers15010295","article-title":"Management of appendix neuroendocrine neoplasms: insights on the current guidelines","volume":"15","author":"Mohamed","year":"2022","journal-title":"Cancers"},{"key":"2026021912532741700_ref6","doi-asserted-by":"crossref","first-page":"915028","DOI":"10.3389\/fonc.2022.915028","article-title":"Goblet cell adenocarcinoma of the appendix: a systematic review and incidence and survival of 1,225 cases from an English cancer registry","volume":"12","author":"Palmer","year":"2022","journal-title":"Front Oncol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/2\/rjag077\/66992455\/rjag077.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/2\/rjag077\/66992455\/rjag077.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T17:53:36Z","timestamp":1771523616000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag077\/8490619"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,31]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,1,31]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag077","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,2]]},"published":{"date-parts":[[2026,1,31]]},"article-number":"rjag077"}}