{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T12:07:35Z","timestamp":1774526855141,"version":"3.50.1"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The management of complex bite wounds, particularly in patients with comorbidities, presents a significant clinical challenge due to the high risk of infection and prolonged healing times. This case report highlights the successful use of intact fish skin grafts as a novel treatment modality for a primary contaminated bite wound at the patient with comorbidities such as diabetes mellitus and rheumatoid artritis with cortisone use. A 54-year-old European female patient with a medical history of rheumatoid arthritis and type 2 diabetes mellitus presented with a large, full-thickness dog bite wound on her right lower leg. Surgical debridement and broad-spectrum antibiotic administration, an intact Kerecis fish skin graft was applied and secured. The application of an intact fish skin xenograft, combined with surgical debridement and appropriate antibiotic therapy, proved to be a highly effective treatment for a complex bite wound in an immunocompromised patient.<\/jats:p>","DOI":"10.1093\/jscr\/rjag197","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T11:06:48Z","timestamp":1774523208000},"source":"Crossref","is-referenced-by-count":0,"title":["The use of intact fish skin grafts in the treatment of acute complicated bite wounds: a case report"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3691-1805","authenticated-orcid":false,"given":"Ivan","family":"Adamovic","sequence":"first","affiliation":[{"name":"Department of Surgery, ASANA Spital Leuggern , 5316 Leuggern ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Dieter","family":"M\u00e4der","sequence":"additional","affiliation":[{"name":"Department of Surgery, ASANA Spital Leuggern , 5316 Leuggern ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Golowan","sequence":"additional","affiliation":[{"name":"Department of Surgery, ASANA Spital Leuggern , 5316 Leuggern ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kostas","family":"Michael","sequence":"additional","affiliation":[{"name":"Department of Surgery, ASANA Spital Leuggern , 5316 Leuggern ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thibika","family":"Sivakumar","sequence":"additional","affiliation":[{"name":"Department of Surgery, ASANA Spital Leuggern , 5316 Leuggern ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Lucian","sequence":"additional","affiliation":[{"name":"Department of Surgery, ASANA Spital Leuggern , 5316 Leuggern ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Kr\u00e4henb\u00fchl","sequence":"additional","affiliation":[{"name":"Department of Surgery, ASANA Spital Leuggern , 5316 Leuggern ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"key":"2026032607064289000_ref1","doi-asserted-by":"publisher","first-page":"4945","DOI":"10.5826\/dpc.1502a4945","article-title":"Omega-3 acellular fish skin grafts for chronic and complicated wounds: a systematic review of efficacy and safety","volume":"15","author":"Karhana","year":"2025","journal-title":"Dermatol Pract Concept"},{"key":"2026032607064289000_ref2","doi-asserted-by":"publisher","first-page":"1775","DOI":"10.3390\/medicina58121775","article-title":"Intact fish skin graft vs. standard of care in patients with neuroischaemic diabetic foot ulcers (KereFish study): an international, multicentre, double-blind, randomised, controlled trial study design and rationale","volume":"58","author":"Dardari","year":"2022","journal-title":"Medicina."},{"key":"2026032607064289000_ref3","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1007\/s00772-018-0428-2","article-title":"The marine Omega3 wound matrix for treatment of complicated wounds: a multicenter experience report","volume":"23","author":"Dorweiler","year":"2018","journal-title":"Gefasschirurgie"},{"key":"2026032607064289000_ref4","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1177\/000313480206800201","article-title":"Necrotizing fasciitis: a fourteen-year retrospective study of 163 consecutive patients","volume":"68","author":"Childers","year":"2002","journal-title":"Am Surg"},{"key":"2026032607064289000_ref5","volume-title":"Oracle Medical Advisory Board & Editors. 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