{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T15:25:37Z","timestamp":1775316337300,"version":"3.50.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T00:00:00Z","timestamp":1775260800000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Spontaneous small bowel perforation is an uncommon initial manifestation of Crohn\u2019s disease, particularly in young adults. We report the case of a 20-year-old woman who presented with a 24-h history of progressive abdominal pain and vomiting. Clinical assessment revealed tachycardia, abdominal distension, absent bowel sounds, and diffuse peritonitis. Laboratory evaluation showed marked leukocytosis, and computed tomography imaging demonstrated features of ileal perforation. After initial resuscitation, urgent surgical exploration identified a perforated ileal segment with associated mesenteric inflammation. Limited ileal resection with primary stapled anastomosis and a protective diverting loop ileostomy were performed. The postoperative course was uneventful, and the patient was discharged on postoperative day six. Histopathology confirmed Crohn\u2019s disease. This case highlights that ileal perforation may be the first presentation of Crohn\u2019s disease and underscores the importance of early recognition and timely surgical management in acute abdomen presentations.<\/jats:p>","DOI":"10.1093\/jscr\/rjag230","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T12:14:39Z","timestamp":1773404079000},"source":"Crossref","is-referenced-by-count":0,"title":["Ileal perforation as the initial presentation of Crohn\u2019s disease in a 20-year-old female: a case report"],"prefix":"10.1093","volume":"2026","author":[{"given":"Faisal M","family":"Rawagah","sequence":"first","affiliation":[{"name":"Department of Surgery, Princess Basma Teaching Hospital , Irbid 21110,","place":["Jordan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahaf E","family":"Farah","sequence":"additional","affiliation":[{"name":"Palestinian Ministry of Health, Jenin District , State of","place":["Palestine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ala\u2019 N","family":"Fari","sequence":"additional","affiliation":[{"name":"Department of Surgery, Princess Basma Teaching Hospital , Irbid 21110,","place":["Jordan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,4,4]]},"reference":[{"key":"2026040410390322100_ref1","doi-asserted-by":"publisher","first-page":"9990","DOI":"10.3748\/wjg.v20.i29.9990","article-title":"Spontaneous free perforation of the small intestine in adults","volume":"20","author":"Freeman","year":"2014","journal-title":"World J Gastroenterol"},{"key":"2026040410390322100_ref2","first-page":"1323","article-title":"Free perforation in Crohn\u2019s disease: a 10-year experience and a review of the literature","volume":"30","author":"Khoury","year":"2015","journal-title":"Int J Color Dis"},{"key":"2026040410390322100_ref3","first-page":"1467","article-title":"Clinical 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Colitis"},{"key":"2026040410390322100_ref10","first-page":"383","article-title":"Postoperative management of Crohn's disease","volume":"152","author":"Regueiro","year":"2017","journal-title":"Gastroenterology"}],"container-title":["Journal of Surgical Case 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