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Laparoscopic appendectomy remains the treatment of choice; however, an open approach may be warranted in cases of severe sepsis, perforation, or extensive intra-abdominal adhesions. We present a case series describing the diagnostic and surgical management of subhepatic appendicitis in a tertiary referral center in Mexico City.<\/jats:p>","DOI":"10.1093\/jscr\/rjag270","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T12:51:35Z","timestamp":1774615895000},"source":"Crossref","is-referenced-by-count":1,"title":["Subhepatic appendicitis mimicking biliary disease: diagnostic pitfalls and laparoscopic management"],"prefix":"10.1093","volume":"2026","author":[{"given":"Cielo S","family":"Silva-Ramos","sequence":"first","affiliation":[{"name":"Department of General Surgery , , Puente de Piedra 150, 140550 Mexico City ,","place":["Mexico"]},{"name":"Hospital M\u00e9dica Sur , , Puente de Piedra 150, 140550 Mexico City ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3263-8290","authenticated-orcid":false,"given":"Kevin 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150, 140550 Mexico City ,","place":["Mexico"]},{"name":"Department of Gastrointestinal Minimally Invasive Surgery , , Puente de Piedra 150, 140550 Mexico City ,","place":["Mexico"]},{"name":"Hospital M\u00e9dica Sur , , Puente de Piedra 150, 140550 Mexico City ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Villegas-Tovar","sequence":"additional","affiliation":[{"name":"Department of General Surgery , , Puente de Piedra 150, 140550 Mexico City ,","place":["Mexico"]},{"name":"Hospital M\u00e9dica Sur , , Puente de Piedra 150, 140550 Mexico City ,","place":["Mexico"]},{"name":"Department of Gastrointestinal Minimally Invasive Surgery , , Puente de Piedra 150, 140550 Mexico City ,","place":["Mexico"]},{"name":"Hospital M\u00e9dica Sur , , Puente de Piedra 150, 140550 Mexico City 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