{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T05:46:19Z","timestamp":1778219179353,"version":"3.51.4"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Tuberculous appendicitis is a rare form of extra-pulmonary tuberculosis that commonly mimics acute appendicitis and is usually diagnosed only after histopathological examination. A 35-year-old man presented with a 1-year history of intermittent abdominal pain and mucoid diarrhea before developing acute right lower quadrant pain due to perforated appendicitis requiring emergency appendectomy. Histopathology revealed caseating granulomatous inflammation consistent with tuberculous appendicitis. The patient completed 6\u00a0months of standard anti-tubercular therapy with complete resolution of symptoms. Due to its nonspecific clinical and radiologic presentation, tuberculous appendicitis is rarely diagnosed preoperatively. Routine histopathological examination of appendectomy specimens remains essential for diagnosis. Combined surgical and medical management typically results in an excellent prognosis.<\/jats:p>","DOI":"10.1093\/jscr\/rjag285","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T11:46:30Z","timestamp":1775043990000},"source":"Crossref","is-referenced-by-count":1,"title":["A very rare presentation of extra-pulmonary tuberculosis discovered through acute appendicitis: a case report"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9496-996X","authenticated-orcid":false,"given":"Samson Y","family":"Murra","sequence":"first","affiliation":[{"name":"Department of Surgery, College of Health Science, Addis Ababa University , Zambia Street, PO Box 565, Addis Ababa ,","place":["Ethiopia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eden H","family":"Hagos","sequence":"additional","affiliation":[{"name":"College of Health Science, Addis Ababa University , Zambia Street, PO Box 565, Addis Ababa ,","place":["Ethiopia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kinfe A","family":"Kassa","sequence":"additional","affiliation":[{"name":"College of Health Science, Addis Ababa University , Zambia Street, PO Box 565, Addis Ababa ,","place":["Ethiopia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abel D","family":"Kuche","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Health Science, Addis Ababa University , Zambia Street, PO Box 565, Addis Ababa ,","place":["Ethiopia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanuel D","family":"Jiffar","sequence":"additional","affiliation":[{"name":"Department of Pathology, College of Health Science, Addis Ababa University , Zambia Street, PO Box 565, Addis Ababa ,","place":["Ethiopia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isa S","family":"Abdo","sequence":"additional","affiliation":[{"name":"Department of Pathology, College of Health Science, Addis Ababa University , Zambia Street, PO Box 565, Addis Ababa ,","place":["Ethiopia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"2026042214123324300_ref1","author":"World Health Organization","year":"2025"},{"key":"2026042214123324300_ref2","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s11894-003-0063-1","article-title":"Gastrointestinal tuberculosis","volume":"5","author":"Sheer","year":"2003","journal-title":"Curr Gastroenterol Rep"},{"key":"2026042214123324300_ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2016\/8356708","article-title":"The role of PCR in diagnosis of a rare appendicular tuberculosis and mini literature review","volume":"2016","author":"Tesfamariam Sengal","year":"2016","journal-title":"Case Rep Gastrointest Med"},{"key":"2026042214123324300_ref4","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1186\/s12876-024-03235-6","article-title":"Immunohistochemistry and real-time polymerase chain reaction: importance in the diagnosis of intestinal tuberculosis in a Peruvian population","volume":"24","author":"Arevalo","year":"2024","journal-title":"BMC Gastroenterol"},{"key":"2026042214123324300_ref5","doi-asserted-by":"publisher","first-page":"rjad373","DOI":"10.1093\/jscr\/rjad373","article-title":"First case of primary appendiceal tuberculosis presented as stump appendicitis","volume":"2023","author":"Mathew","year":"2023","journal-title":"J Surg Case Rep"},{"key":"2026042214123324300_ref6","doi-asserted-by":"publisher","first-page":"298","DOI":"10.14744\/nci.2019.93797","article-title":"Primary tuberculosis of the appendix: common disease with rare location \u2013 a rare case report from rural India","volume":"7","author":"Krishna","year":"2019","journal-title":"North Clin Istanb"},{"key":"2026042214123324300_ref7","doi-asserted-by":"publisher","first-page":"100228","DOI":"10.1016\/j.jctube.2021.100228","article-title":"Tuberculous appendicitis: a review of reported cases over the past 10 years","volume":"23","author":"Hubbard","year":"2021","journal-title":"J Clin Tuberc Mycobact Dis"},{"key":"2026042214123324300_ref8","doi-asserted-by":"publisher","first-page":"129","DOI":"10.2147\/IMCRJ.S158074","article-title":"Perforated tuberculous appendicitis: a rare case report","volume":"11","author":"Gonie","year":"2018","journal-title":"Int Med Case Rep J"},{"key":"2026042214123324300_ref9","doi-asserted-by":"publisher","first-page":"37","DOI":"10.46347\/JMSH.2016.v02i02.007","article-title":"Isolated tubercular inflammation of the appendix: a case report","volume":"02","author":"R","year":"2016","journal-title":"J Med Sci Health"},{"key":"2026042214123324300_ref10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2015\/534838","article-title":"An uncommon case of chronic tubercular appendicitis","volume":"2015","author":"Maharjan","year":"2015","journal-title":"Case Rep Pathol"},{"key":"2026042214123324300_ref11","volume-title":"WHO Operational Handbook on Tuberculosis. Module 4: Treatment - Drug-Susceptible Tuberculosis Treatment","author":"World Health Organization","year":"2022","edition":"1"},{"key":"2026042214123324300_ref12","doi-asserted-by":"publisher","first-page":"e82081","DOI":"10.7759\/cureus.82081","article-title":"Idiopathic granulomatous appendicitis: a case report and review of the literature","volume":"17","author":"Awad","year":"2025","journal-title":"Cureus"},{"key":"2026042214123324300_ref13","doi-asserted-by":"publisher","first-page":"e119","DOI":"10.1016\/j.cireng.2013.09.033","article-title":"Granulomatous appendicitis: an uncommon cause of acute abdomen","volume":"93","author":"Alhambra Rodr\u00edguez De Guzm\u00e1n","year":"2015","journal-title":"Cir Esp Engl Ed"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/4\/rjag285\/68138008\/rjag285.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/4\/rjag285\/68138008\/rjag285.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T18:12:38Z","timestamp":1776881558000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag285\/8661036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,1]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag285","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,4]]},"published":{"date-parts":[[2026,4,1]]},"article-number":"rjag285"}}