{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:53:42Z","timestamp":1777542822502,"version":"3.51.4"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Schwannomas are benign peripheral nerve tumors, with gastrointestinal involvement being rare and ileal origin exceptionally uncommon. Their nonspecific symptoms often mimic acute abdominal conditions, complicating preoperative diagnosis. A 40-year-old female presented with acute right iliac fossa pain, nausea, vomiting, and fever, initially suggestive of acute appendicitis. Ultrasonography showed a blind-ending tubular structure. During emergency appendicectomy, the appendix appeared normal, but an exophytic ileal mass was identified. Segmental ileal resection with primary anastomosis was performed. Histopathology revealed spindle cells with Antoni A and B areas, and immunohistochemistry was strongly positive for S-100, confirming schwannoma. Postoperative computed tomography of abdomen and pelvis showed no additional lesions. The patient also had multiple cutaneous lesions and was referred to dermatology for further evaluation. Ileal schwannoma is a rare cause of acute abdomen and may mimic appendicitis. Histopathology and immunohistochemistry are essential for diagnosis, while complete surgical excision is curative. Postoperative imaging ensures comprehensive assessment.<\/jats:p>","DOI":"10.1093\/jscr\/rjag311","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T11:31:22Z","timestamp":1776771082000},"source":"Crossref","is-referenced-by-count":0,"title":["Incidental ileal schwannoma mimicking acute appendicitis: an intraoperative diagnostic challenge"],"prefix":"10.1093","volume":"2026","author":[{"given":"Hafiz Syed Zaigham Ali","family":"Shah","sequence":"first","affiliation":[{"name":"General Surgery Department, Aberdeen Royal Infirmary\/ University of Aberdeen , King's Street, Aberdeen AB24 3FX ,","place":["United Kingdom"]},{"name":"King Edward Medical University\/ Mayo Hospital , Nila Gumbad Road, Lahore 5400, Punjab ,","place":["Pakistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Musaab","sequence":"additional","affiliation":[{"name":"King Edward Medical University\/ Mayo Hospital , Nila Gumbad Road, Lahore 5400, Punjab ,","place":["Pakistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Salman Hussain","family":"Zaidi","sequence":"additional","affiliation":[{"name":"King Edward Medical University\/ Mayo Hospital , Nila Gumbad Road, Lahore 5400, Punjab ,","place":["Pakistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayesha","family":"Mahmood","sequence":"additional","affiliation":[{"name":"King Edward Medical University\/ Mayo Hospital , Nila Gumbad Road, Lahore 5400, Punjab ,","place":["Pakistan"]},{"name":"Aberdeen Royal Infirmary, University of Aberdeen , King's Street, Aberdeen AB24 3FX ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Saqib Ali","family":"Shah","sequence":"additional","affiliation":[{"name":"King Edward Medical University\/ Mayo Hospital , Nila Gumbad Road, Lahore 5400, Punjab ,","place":["Pakistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noor-Ul-Ain","family":"Mujahid","sequence":"additional","affiliation":[{"name":"King Edward Medical University\/ Mayo Hospital , Nila Gumbad Road, Lahore 5400, Punjab ,","place":["Pakistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"2026042813245998200_ref1","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1007\/s12663-009-0069-9","article-title":"Schwannomas of the head and neck: a case series","volume":"8","author":"Baliga","year":"2009","journal-title":"J Maxillofac Oral Surg"},{"key":"2026042813245998200_ref2","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/j.suc.2022.04.007","article-title":"Benign neurogenic tumors","volume":"102","author":"Farma","year":"2022","journal-title":"Surg Clin North Am"},{"key":"2026042813245998200_ref3","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1097\/00005537-200404000-00016","article-title":"Vestibular schwannoma surgery outcomes: our multidisciplinary experience in 400 cases over 17 years","volume":"114","author":"Darrouzet","year":"2004","journal-title":"Laryngoscope"},{"key":"2026042813245998200_ref4","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12893-018-0379-2","article-title":"Gastrointestinal schwannomas: a rare but important differential diagnosis of mesenchymal tumors of the gastrointestinal tract","volume":"18","author":"Mekras","year":"2018","journal-title":"BMC Surg"},{"key":"2026042813245998200_ref5","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1080\/00015458.2015.11681120","article-title":"Appendicular schwannoma presenting as acute appendicitis","volume":"115","author":"Kamp","year":"2015","journal-title":"Acta Chir Belg"},{"key":"2026042813245998200_ref6","doi-asserted-by":"publisher","first-page":"499","DOI":"10.17235\/reed.2022.8684\/2022","article-title":"Sigmoid colon schwannoma simulating colon cancer","volume":"114","author":"Armas","year":"2022","journal-title":"Rev Esp Enferm Dig"},{"key":"2026042813245998200_ref7","doi-asserted-by":"publisher","first-page":"E330","DOI":"10.12816\/0003247","article-title":"Asymptomatic ileal schwannoma presenting as a mesenteric tumour: case report and review of literature","volume":"13","author":"Khan","year":"2013","journal-title":"Sultan Qaboos Univ Med J"},{"key":"2026042813245998200_ref8","doi-asserted-by":"publisher","first-page":"638","DOI":"10.3748\/wjg.14.638","article-title":"Ileal schwannoma developing into ileocolic intussusception","volume":"14","author":"Hirasaki","year":"2008","journal-title":"World J Gastroenterol"},{"key":"2026042813245998200_ref9","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.2169\/internalmedicine.42.1178","article-title":"Ileal schwannoma in which blood loss scintigraphy was useful for diagnosis","volume":"42","author":"Nagai","year":"2003","journal-title":"Intern Med"},{"key":"2026042813245998200_ref10","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1186\/s12957-018-1427-1","article-title":"Schwannoma of the colon and rectum: a systematic literature review","volume":"16","author":"Bohlok","year":"2018","journal-title":"World J Surg Oncol"},{"key":"2026042813245998200_ref11","volume-title":"StatPearls. Treasure Island (FL)","author":"Le","year":"2026"},{"key":"2026042813245998200_ref12","doi-asserted-by":"publisher","first-page":"408","DOI":"10.47717\/turkjsurg.2021.4286","article-title":"Gastrointestinal tract schwannomas and brief review of literature","volume":"37","author":"\u00c7olak","year":"2021","journal-title":"Turk J Surg"},{"key":"2026042813245998200_ref13","doi-asserted-by":"publisher","first-page":"e22343","DOI":"10.7759\/cureus.22343","article-title":"Incidental intestinal schwannoma in a patient of ulcerative colitis with adhesive intestinal obstruction: a case report","volume":"14","author":"Khanduri","year":"2022","journal-title":"Cureus"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/4\/rjag311\/68180496\/rjag311.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/4\/rjag311\/68180496\/rjag311.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:25:09Z","timestamp":1777397109000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag311\/8664205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,1]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag311","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,4]]},"published":{"date-parts":[[2026,4,1]]},"article-number":"rjag311"}}