{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T11:08:20Z","timestamp":1787656100138,"version":"build-2736575974"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Giant uterine leiomyomas (&amp;gt;10\u00a0cm) are uncommon in the modern imaging era and may mimic ovarian malignancy due to their size and heterogeneous appearance, posing a diagnostic and therapeutic challenge. A 34-year-old nulliparous woman presented with progressive abdominal distension and pelvic pressure. Imaging revealed a 19\u2009\u00d7\u200914\u00a0cm multinodular uterine mass with heterogeneous features and preserved surrounding fat planes. Given the patient\u2019s strong desire for uterine preservation, an open abdominal myomectomy was performed. A highly vascular, multicompartmental leiomyoma arising from the uterine body was successfully enucleated with vasopressin-assisted hemostasis and meticulous multilayer myometrial reconstruction. Estimated blood loss was 1000\u00a0ml without transfusion. Histopathology confirmed a benign leiomyoma. The postoperative course was uneventful. This case highlights that, despite their size and complexity, giant multicompartmental leiomyomas can be safely managed with uterine-preserving myomectomy in carefully selected patients. Adequate preoperative assessment, intraoperative vascular control, and advanced reconstructive techniques are critical to guide surgical decision-making and optimize outcomes.<\/jats:p>","DOI":"10.1093\/jscr\/rjag314","type":"journal-article","created":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T11:34:47Z","timestamp":1777116887000},"source":"Crossref","is-referenced-by-count":1,"title":["Giant uterine leiomyoma successfully managed by surgical excision: a case report"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8383-4099","authenticated-orcid":false,"given":"Luis F","family":"Llerena Freire","sequence":"first","affiliation":[{"name":"Department of Digestive Surgery, Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (FMUSP) , Av. Dr. En\u00e9as Carvalho de Aguiar, 255, Cerqueira C\u00e9sar, S\u00e3o Paulo, SP 05403-000 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cintya A","family":"Llerena Ojeda","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Hospital de Especialidades Eugenio Espejo , Av. Gran Colombia y Yaguachi, Quito 170136, Pichincha ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria A","family":"Llerena Morales","sequence":"additional","affiliation":[{"name":"Department of Teaching, Faculty of Medicine, Pontificia Universidad Cat\u00f3lica del Ecuador , Av. Manuelita S\u00e1enz y Av. Atahualpa, Ambato 180150, Tungurahua ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela D","family":"Vela Arias","sequence":"additional","affiliation":[{"name":"Department of Teaching, Faculty of Medicine, Pontificia Universidad Cat\u00f3lica del Ecuador , Av. Manuelita S\u00e1enz y Av. Atahualpa, Ambato 180150, Tungurahua ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2772-6328","authenticated-orcid":false,"given":"Joaury L","family":"Arteaga Ter\u00e1n","sequence":"additional","affiliation":[{"name":"Universidad de Guayaquil , Cdla. Universitaria Salvador Allende, Av. Delta, Guayaquil 090150, Guayas ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia Y","family":"Valle Acurio","sequence":"additional","affiliation":[{"name":"Department of Teaching, Faculty of Medical Sciences, Universidad Central del Ecuador , El Dorado Campus, Iquique 132, Quito 170136, Pichincha ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra C","family":"Lopez","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Surgical Oncology, Universidad Tecnol\u00f3gica Indoam\u00e9rica , Machala y Sabanilla, Quito 170301, Pichincha ,","place":["Ecuador"]},{"name":"Department of Surgical Oncology, SOLCA N\u00facleo Quito, Hospital Oncol\u00f3gico Sol\u00f3n Espinosa Ayala , Av. Eloy Alfaro N73-10 y Los Pinos, Quito 170504, Pichincha ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia D C","family":"Aguirre V\u00e1zconez","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Hospital del IESS Ambato , Av. Cevallos y Espejo, Ambato 180150, Tungurahua ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayely G","family":"Silva Vizuete","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pontificia Universidad Cat\u00f3lica del Ecuador , Av. Manuelita S\u00e1enz y Av. Atahualpa, Ambato 180150, Tungurahua ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivanova D","family":"Ruiz Solis","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pontificia Universidad Cat\u00f3lica del Ecuador , Av. Manuelita S\u00e1enz y Av. 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