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Following endoscopic sphincterotomy with stone extraction and subsequent laparoscopic cholecystectomy, she was discharged home. She re-presented 6 days later with constipation and lower abdominal pain. Repeat imaging revealed large bowel obstruction with marked cecal dilatation due to migration of a gallstone impacted at the site of the previously identified colonic narrowing. Emergency Hartmann\u2019s procedure was performed. Histopathology confirmed a moderately differentiated adenocarcinoma of the colon (pT4aN0R0). This case highlights a rare complication of gallstone migration resulting in colonic obstruction, which likely expedited the diagnosis and definitive management of underlying colorectal malignancy.<\/jats:p>","DOI":"10.1093\/jscr\/rjag320","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T11:23:26Z","timestamp":1776079406000},"source":"Crossref","is-referenced-by-count":1,"title":["A persistent gallstone\u2014an unusual cause of colonic obstruction in sigmoid adenocarcinoma"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4966-5839","authenticated-orcid":false,"given":"Benedict","family":"Blacket","sequence":"first","affiliation":[{"name":"University of Oxford , Department of Physiology, Anatomy and Genetics, Sherrington Rd, Oxford , OX1 3PT,","place":["United Kingdom"]},{"name":"University of Oxford Hospitals NHS Foundation Trust , Headley Way, Headington, Oxford OX3 9DU ,","place":["United 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