{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T08:12:52Z","timestamp":1778314372325,"version":"3.51.4"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Duodeno-jejunal intussusception is highly unusual because of the retroperitoneal fixation of the duodenum, with only a limited number of cases documented in the literature. Furthermore, intussusception caused by a malignant ampullary lead point has not been reported previously. We present the case of a 58-year-old man who presented with obstructive jaundice for 8\u00a0months with no features of intestinal obstruction. Computed tomography imaging revealed dilation and deformation of the pancreaticobiliary tree due to duodenal intussusception. Intraoperative findings confirmed duodeno-jejunal intussusception with an ampullary mass acting as the lead point, which was confirmed to be adenocarcinoma upon pathological examination. The patient successfully underwent pylorus-preserving pancreaticoduodenectomy (Whipple procedure) with Child\u2019s reconstruction. Although duodenal intussusception is rarely encountered, clinicians must consider it in the differential diagnosis of unexplained biliary obstruction, even in the absence of intestinal obstruction features. A comprehensive diagnostic evaluation and tailored surgical approach are essential for optimal management.<\/jats:p>","DOI":"10.1093\/jscr\/rjag356","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T11:30:41Z","timestamp":1777289441000},"source":"Crossref","is-referenced-by-count":0,"title":["Duodeno-jejunal intussusception: an unusual manifestation of ampullary adenocarcinoma"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2892-0965","authenticated-orcid":false,"given":"Hajer A","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Surgery, Muhimbili University of Health and Allied Sciences , 9 United Nations Road, Upanga West, PO Box 65001, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel W","family":"Kitua","sequence":"additional","affiliation":[{"name":"Department of Surgery, Muhimbili University of Health and Allied Sciences , 9 United Nations Road, Upanga West, PO Box 65001, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ally H","family":"Mwanga","sequence":"additional","affiliation":[{"name":"Department of Surgery, Muhimbili University of Health and Allied Sciences , 9 United Nations Road, Upanga West, PO Box 65001, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Godbless E","family":"Massawe","sequence":"additional","affiliation":[{"name":"Department of Surgery, Muhimbili National Hospital , Malik Road, Upanga West, PO Box 65000, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazungu B","family":"Kahindi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Muhimbili University of Health and Allied Sciences , 9 United Nations Road, Upanga West, PO Box 65001, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed A","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Surgery, Muhimbili University of Health and Allied Sciences , 9 United Nations Road, Upanga West, PO Box 65001, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Mpemba","sequence":"additional","affiliation":[{"name":"Department of Radiology and Diagnostic Imaging, Muhimbili National Hospital , Malik Road, Upanga West, PO Box 65000, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick R","family":"Lyimo","sequence":"additional","affiliation":[{"name":"Department of Radiology and Diagnostic Imaging, Muhimbili National Hospital , Malik Road, Upanga West, PO Box 65000, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex B","family":"Mashaka","sequence":"additional","affiliation":[{"name":"Department of Pathology, Muhimbili University of Health and Allied Sciences , 9 United Nations Road, Upanga West, PO Box 65001, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah K","family":"Nyagabona","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Oncology Unit, Muhimbili National Hospital , Malik Road, Upanga West, PO Box 65000, Dar-es-salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cameron E","family":"Gaskill","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of California Davis, Center for Global Surgery , 2335 Stockton Boulevard, Sacramento, CA 95817 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,5,7]]},"reference":[{"key":"2026050903564544100_ref1","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1308\/003588414X13824511650579","article-title":"Small bowel intussusception in adults","volume":"96","author":"Potts","year":"2014","journal-title":"Ann R Coll Surg Engl"},{"key":"2026050903564544100_ref2","doi-asserted-by":"publisher","first-page":"107085","DOI":"10.1016\/j.ijscr.2022.107085","article-title":"Intussusception of the third portion of the duodenum secondary to a primary duodenal malignancy: a case report","volume":"94","author":"Matsuura","year":"2022","journal-title":"Int J Surg Case Rep"},{"key":"2026050903564544100_ref3","doi-asserted-by":"publisher","first-page":"731","DOI":"10.3892\/mco.2016.1061","article-title":"Experience in clinical diagnosis and treatment of duodenal 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Rep"},{"key":"2026050903564544100_ref7","doi-asserted-by":"publisher","first-page":"e244034","DOI":"10.1136\/bcr-2021-244034","article-title":"Adenocarcinoma of the fourth portion of duodenum presenting as intussusception: an unusual manifestation of rare pathology","volume":"14","author":"Varshney","year":"2021","journal-title":"BMJ Case Rep"},{"key":"2026050903564544100_ref8","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.4103\/0973-1482.154068","article-title":"Duodenoduodenal intussusception: report of three challenging cases with literature review","volume":"11","author":"Pradhan","year":"2015","journal-title":"J Cancer Res Ther"},{"key":"2026050903564544100_ref9","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1007\/s11605-008-0509-8","article-title":"Duodenoduodenal intussusception","volume":"13","author":"Singhal","year":"2009","journal-title":"J Gastrointest 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