{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:44:55Z","timestamp":1785451495420,"version":"3.56.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Amyloidosis is a condition characterized by extracellular deposition of insoluble, proteinaceous material with \u03b2-pleated ultrastructure. Localized head neck amyloidosis is rare with 41 cases of nasopharyngeal amyloidosis reported. A 56-year old male, with a history of T2 N1 M0 HPV positive left tonsillar squamous cell carcinoma, under surveillance post-treatment, had an incidental finding of a nasopharyngeal amyloidosis (AL lambda), involving the right lateral wall. This was resected with combined trans-nasal and transoral robotic-assisted surgery (TORS) approach, avoiding palatal split while using suction catheter for soft palate retraction. This is the first case of nasopharyngeal amyloidosis treated with this novel technique. The patient had complete resolution of swallowing with good palatal function by 2\u00a0months post-procedure and a 1\u00a0year recurrence free survival. TORS is a great adjunct for nasopharyngeal resections where conventional methods maybe limited. The combined approach added excellent 3D visualization and precise dissection without the sequel of palatal splitting.<\/jats:p>","DOI":"10.1093\/jscr\/rjag392","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T11:52:39Z","timestamp":1781178759000},"source":"Crossref","is-referenced-by-count":1,"title":["A novel combined approach: trans-nasal endoscopic and transoral robotic-assisted resection of nasopharyngeal amyloidosis"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2957-3083","authenticated-orcid":false,"given":"Ishita","family":"Sen","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery, Imperial College London, Imperial College Healthcare NHS Trust , Fulham Palace Road, London W6 8RF ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1294-2527","authenticated-orcid":false,"given":"Zaid","family":"Awad","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Imperial College London, Imperial College Healthcare NHS Trust , Fulham Palace Road, London W6 8RF ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,14]]},"reference":[{"key":"2026062506241739300_ref1","first-page":"25","article-title":"Localised, isolated amyloidosis of the nose and paranasal sinuses","volume":"5","author":"Iliev","year":"2019","journal-title":"J Otolaryng Head Neck Surg"},{"key":"2026062506241739300_ref2","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.amjoto.2006.08.009","article-title":"Localized amyloidosis masquerading as nasopharyngeal tumor: a review","volume":"28","author":"Panda","year":"2007","journal-title":"Am J Otolaryngol"},{"key":"2026062506241739300_ref3","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1007\/s00432-024-05873-5","article-title":"Nasopharyngeal amyloidoma: report of three cases and review of the literature","volume":"150","author":"Zuo","year":"2024","journal-title":"J Cancer Res Clin Oncol"},{"key":"2026062506241739300_ref4","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.1002\/lary.21059","article-title":"Transoral robotic resection of recurrent nasopharyngeal carcinoma","volume":"120","author":"Wei","year":"2010","journal-title":"Laryngoscope"},{"key":"2026062506241739300_ref5","doi-asserted-by":"publisher","first-page":"91","DOI":"10.5114\/wo.2022.118240","article-title":"Current indications and patient selection for transoral robotic surgery in head and neck cancer - a brief review","volume":"26","author":"Niewinski","year":"2022","journal-title":"Contemporary oncology (Poznan, Poland)"},{"key":"2026062506241739300_ref6","doi-asserted-by":"publisher","first-page":"E2","DOI":"10.3171\/2014.7.FOCUS14353","article-title":"The combined endonasal and transoral approach for the management of skull base and nasopharyngeal pathology: a case series","volume":"37","author":"Sreenath","year":"2014","journal-title":"Neurosurg Focus"},{"key":"2026062506241739300_ref7","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.1002\/hed.21731","article-title":"Combined transnasal endoscopic and transoral robotic resection of recurrent nasopharyngeal carcinoma","volume":"34","author":"Yin Tsang","year":"2012","journal-title":"Head Neck"},{"key":"2026062506241739300_ref8","doi-asserted-by":"publisher","first-page":"552","DOI":"10.3760\/cma.j.cn115330-20210804-00519","volume":"57","author":"Han","year":"2022","journal-title":"Chin J Otorhinolaryngol Head Neck Surg"},{"key":"2026062506241739300_ref9","doi-asserted-by":"publisher","first-page":"e14","DOI":"10.1055\/a-2466-7414","article-title":"A novel technique for nasopharyngeal stenosis repair: combined transoral robotic and endonasal approaches for enhanced visualization and surgical precision","volume":"86","author":"Wagner","year":"2025","journal-title":"J Neurol Surg Rep"},{"key":"2026062506241739300_ref15","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.surge.2016.09.004","article-title":"Role of transoral robotic surgery in current head & neck practice","volume":"15","author":"Hamilton","year":"2017","journal-title":"Surgeon"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/6\/rjag392\/68610088\/rjag392.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/6\/rjag392\/68610088\/rjag392.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T10:24:46Z","timestamp":1782383086000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag392\/8707715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,31]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,5,31]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag392","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,6]]},"published":{"date-parts":[[2026,5,31]]},"article-number":"rjag392"}}