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We present a case of a 77-year-old male with a history of polytrauma and prolonged immobility, who developed severe hyperphosphatemia and secondary hypocalcemia following rectal administration of a phosphate enema. The case highlights hyperphosphatemia as a potential complication of phosphate absorption and underlines the importance of early recognition of symptoms and prompt treatment.<\/jats:p>","DOI":"10.1093\/jscr\/rjag462","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T11:32:55Z","timestamp":1780399975000},"source":"Crossref","is-referenced-by-count":0,"title":["Acute severe hyperphosphatemia and secondary hypocalcemia after phosphate enema administration in a constipated post-trauma patient recovering from pelvic surgery: a case report"],"prefix":"10.1093","volume":"2026","author":[{"given":"Karoline B","family":"Br\u00e4uner","sequence":"first","affiliation":[{"name":"Department of Surgery, Slagelse Hospital , F\u00e6lledvej 11, Slagelse 4200 ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hjalte L","family":"Berthelsen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Slagelse Hospital , F\u00e6lledvej 11, Slagelse 4200 ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne G","family":"Vedel","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Slagelse Hospital , F\u00e6lledvej 2, Slagelse 4200 ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,13]]},"reference":[{"key":"2026062506221198200_ref1","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1007\/s00383-012-3124-4","article-title":"Severe hyperphosphatemia after administration of sodium-phosphate containing laxatives in children: case series and systematic review of literature","volume":"28","author":"Ladenhauf","year":"2012","journal-title":"Pediatr Surg Int"},{"key":"2026062506221198200_ref2","first-page":"1414","article-title":"Akut hyperfosfat\u00e6mi hos en dialysepatient efter indgift af 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