{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T01:43:23Z","timestamp":1791510203531,"version":"4.3.4"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T00:00:00Z","timestamp":1782518400000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009164","name":"Moffitt Cancer Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009164","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>MN1\u2013BEND2 fusion is a defining molecular alteration in astroblastoma, MN1-altered, and is rarely identified in extracranial tumors. To date, only one soft-tissue sarcoma harboring this fusion has been reported. We present the second known case, arising in the deep pelvis of a 34-year-old woman with osseous and neural foraminal invasion. Imaging demonstrated a destructive pelvic mass, and biopsy revealed a spindle cell sarcoma with a myofibroblastic immunophenotype. The patient underwent neoadjuvant radiotherapy followed by radical resection. Histologic evaluation showed heterogeneous morphology, and molecular testing confirmed MN1\u2013BEND2 fusion. The patient remains without evidence of recurrence on short-term follow-up. This case expands the clinicopathologic spectrum of MN1\u2013BEND2\u2013associated soft-tissue sarcomas and highlights the importance of molecular testing in undifferentiated spindle-cell tumors to ensure accurate diagnosis and classification.<\/jats:p>","DOI":"10.1093\/jscr\/rjag481","type":"journal-article","created":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T11:31:21Z","timestamp":1782041481000},"source":"Crossref","is-referenced-by-count":1,"title":["Soft-tissue sarcoma with MN1\u2013BEND2 fusion: second reported case and comparative analysis"],"prefix":"10.1093","volume":"2026","author":[{"given":"Nicole","family":"Nagib","sequence":"first","affiliation":[{"name":"Moffitt Cancer Center , Tampa, FL 33612 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3756-8137","authenticated-orcid":false,"given":"Abanoub","family":"Gabra","sequence":"additional","affiliation":[{"name":"Department of Pathology, Moffitt Cancer Center , Tampa, FL 33612 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Joyce","sequence":"additional","affiliation":[{"name":"Department of Surgery, Moffitt Cancer Center , Tampa, FL 33612 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Voss","sequence":"additional","affiliation":[{"name":"Department of Surgery, Moffitt Cancer Center , Tampa, FL 33612 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Becker-Weidman","sequence":"additional","affiliation":[{"name":"Department of Radiology, Moffitt Cancer Center , Tampa, FL 33612 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn","family":"Bui","sequence":"additional","affiliation":[{"name":"Department of Pathology, Moffitt Cancer Center , Tampa, FL 33612 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,27]]},"reference":[{"key":"2026062713222630000_ref1","first-page":"232","volume-title":"WHO Classification of Tumours Editorial Board (Ed.), WHO Classification of Tumours: Central Nervous System Tumours","author":"Brat","year":"2021","edition":"5th"},{"key":"2026062713222630000_ref2","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1002\/gcc.23028","article-title":"Soft-tissue sarcoma with MN1-BEND2 fusion: a case report and comparison with astroblastoma","volume":"61","author":"Yoshida","year":"2022","journal-title":"Genes Chromosomes Cancer"},{"key":"2026062713222630000_ref3","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.cell.2016.01.015","article-title":"New brain tumor entities emerge from molecular classification of CNS-PNETs","volume":"164","author":"Sturm","year":"2016","journal-title":"Cell"},{"key":"2026062713222630000_ref4","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1111\/bpa.12565","article-title":"Astroblastoma: a distinct tumor entity characterized by alterations of the X chromosome and MN1 rearrangement","volume":"28","author":"Hirose","year":"2018","journal-title":"Brain Pathol"},{"key":"2026062713222630000_ref5","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1007\/s00401-021-02354-8","article-title":"PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum","volume":"142","author":"Alhalabi","year":"2021","journal-title":"Acta Neuropathol"},{"key":"2026062713222630000_ref6","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/s41379-021-00910-x","article-title":"Identification of novel SSX1 fusions in synovial sarcoma","volume":"35","author":"Yoshida","year":"2022","journal-title":"Mod Pathol"}],"container-title":["Journal of Surgical Case 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