{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:03:14Z","timestamp":1790892194280,"version":"4.1.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Giant inguinoscrotal hernias (GIH) are rare and are often complicated by loss of domain (LOD), incarceration, and chronic soft tissue changes. We report a 51-year-old male with a 30-year history of a progressively enlarging left inguinoscrotal hernia extending to the knee, who presented with abdominal pain and leukocytosis. Computed tomography demonstrated marked LOD without strangulation. Intraoperatively, a large scrotal abscess with soft tissue necrosis was identified in the setting of chronic dense bowel adhesions and spermatic cord involvement. Management required combined abdominal and inguinoscrotal approaches, small bowel resection with anastomosis, orchiectomy, and bilateral anterior component separation with absorbable biosynthetic mesh reinforcement. Due to concern for abdominal compartment syndrome following closure, the patient required planned postoperative intubation and paralysis. He was discharged on postoperative day 9 without major complications. This case highlights the complexity of GIH repair and underscores the importance of individualized operative planning and multidisciplinary perioperative management.<\/jats:p>","DOI":"10.1093\/jscr\/rjag507","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T11:41:16Z","timestamp":1780746076000},"source":"Crossref","is-referenced-by-count":1,"title":["Giant inguinoscrotal hernia with loss of domain complicated by scrotal abscess requiring bowel resection, orchiectomy, and component separation"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2248-424X","authenticated-orcid":false,"given":"Amy","family":"Wen","sequence":"first","affiliation":[{"name":"Department of Surgery, Rush University Medical Center , 1725 West Harrison Street, Chicago, IL 60612 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Millikan","sequence":"additional","affiliation":[{"name":"Department of Surgery, Rush University Medical Center , 1725 West Harrison Street, Chicago, IL 60612 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"2026062613363763100_ref1","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1016\/S0140-6736(03)14746-0","article-title":"Hernias: inguinal and incisional","volume":"362","author":"Kingsnorth","year":"2003","journal-title":"Lancet"},{"key":"2026062613363763100_ref2","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s10029-025-03356-1","article-title":"Management of giant inguinal hernia; report of four cases and review of literature","volume":"29","author":"Olaoye","year":"2025","journal-title":"Hernia"},{"key":"2026062613363763100_ref3","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1007\/s10029-014-1324-7","article-title":"Giant inguinal hernia: the challenging hug technique","volume":"19","author":"Cavalli","year":"2015","journal-title":"Hernia"},{"key":"2026062613363763100_ref4","doi-asserted-by":"publisher","first-page":"e74599","DOI":"10.7759\/cureus.74599","article-title":"Giant Inguino-scrotal hernia with loss of domain: surgical report and literature review","volume":"16","author":"Koller","year":"2024","journal-title":"Cureus"},{"key":"2026062613363763100_ref5","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1007\/s00268-019-05317-z","article-title":"Definitions for loss of domain: an international delphi consensus of expert surgeons","volume":"44","author":"Parker","year":"2020","journal-title":"World J Surg"},{"key":"2026062613363763100_ref6","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1007\/s10029-024-02992-3","article-title":"Intra-abdominal hypertension and compartment syndrome after complex hernia repair","volume":"28","author":"Van Hoef","year":"2024","journal-title":"Hernia"},{"key":"2026062613363763100_ref7","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1097\/PRS.0000000000001621","article-title":"Permissible intraabdominal hypertension following complex abdominal wall reconstruction","volume":"136","author":"Petro","year":"2015","journal-title":"Plast Reconstr Surg"},{"key":"2026062613363763100_ref8","doi-asserted-by":"publisher","first-page":"6","DOI":"10.4103\/ijawhs.ijawhs_4_23","article-title":"Outcomes in the surgical management of giant inguinal hernias","volume":"6","author":"Oyewale","year":"2023","journal-title":"Int J Abdom Wall Hernia Surg"},{"key":"2026062613363763100_ref9","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1186\/s12893-017-0331-x","article-title":"Surgical treatment strategies for giant inguinoscrotal hernia - a case report with review of the literature","volume":"17","author":"Staubitz","year":"2017","journal-title":"BMC Surg"},{"key":"2026062613363763100_ref10","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1089\/lap.2019.0669","article-title":"Combination of preoperative progressive pneumoperitoneum and botulinum toxin a enables the laparoscopic transabdominal preperitoneal approach for repairing giant inguinoscrotal hernias","volume":"30","author":"Tang","year":"2020","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"2026062613363763100_ref11","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1007\/s10029-026-03654-2","article-title":"Laparoscopic application of intraoperative fascial traction (fasciotens\u24c7Hernia) during loss of domain scrotal hernia repair: a European multicenter case series with technical details and preliminary results","volume":"30","author":"Barbosa","year":"2026","journal-title":"Hernia"},{"key":"2026062613363763100_ref12","doi-asserted-by":"publisher","first-page":"e93330","DOI":"10.7759\/cureus.93330","article-title":"A massive sliding inguinal hernia containing the entire right colon with caecal perforation: a rare surgical challenge","volume":"17","author":"Ahmed","year":"2025","journal-title":"Cureus"},{"key":"2026062613363763100_ref13","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/S0025-6196(25)18893-9","article-title":"Scrotal reconstruction for giant inguinal hernias","volume":"57","author":"Hodgkinson","year":"1982","journal-title":"Mayo Clin Proc"},{"key":"2026062613363763100_ref14","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1007\/s00595-009-4125-3","article-title":"Challenging surgical management of a giant inguinoscrotal hernia: report of a case","volume":"40","author":"Vasiliadis","year":"2010","journal-title":"Surg Today"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/6\/rjag507\/68628759\/rjag507.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/6\/rjag507\/68628759\/rjag507.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T17:36:41Z","timestamp":1782495401000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag507\/8719120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,31]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,5,31]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag507","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,6]]},"published":{"date-parts":[[2026,5,31]]},"article-number":"rjag507"}}