{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T11:07:12Z","timestamp":1784027232369,"version":"3.55.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Primary visceral extraskeletal Ewing sarcoma is exceedingly rare; gastric and omental primaries pose diagnostic challenges by mimicking benign gastrointestinal conditions. We present a 17-year-old with a gastric mass and a 12-year-old with an omental primary, mismanaged as iron deficiency anemia and functional constipation, respectively. Diagnoses were confirmed via imaging, endoscopy, and histopathology with EWSR1::ERG and EWSR1::FLI1 fusion detection. Both received neoadjuvant chemotherapy for cytoreduction and organ-sparing surgery. The first underwent wedge gastrectomy with positive serosal margins, lymphovascular invasion, and nodal involvement necessitating adjuvant therapy. The second, presenting with peritoneal sarcomatosis and bone marrow metastasis, underwent en bloc enterectomy, achieving 5-year disease-free survival despite toxicities requiring early discontinuation. These cases underscore radiographic-pathologic dissonance, wherein imaging regression may not reflect biological clearance, and high suspicion for small round blue cell tumors in refractory presentations. Multimodal integration of molecular diagnostics, induction chemotherapy, and aggressive cytoreduction optimizes visceral extraskeletal Ewing sarcoma outcomes.<\/jats:p>","DOI":"10.1093\/jscr\/rjag581","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T10:50:42Z","timestamp":1784026242000},"source":"Crossref","is-referenced-by-count":0,"title":["Extraskeletal Ewing sarcoma primarily arising in the stomach and omentum in children: a case series"],"prefix":"10.1093","volume":"2026","author":[{"given":"Isabel M","family":"Kiko","sequence":"first","affiliation":[{"name":"Department of General Surgery, Summa Health Systems , Akron, OH ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3033-8026","authenticated-orcid":false,"given":"Vineet","family":"Narayanan","sequence":"additional","affiliation":[{"name":"College of Medicine, Northeast Ohio Medical University , Rootstown, OH ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bader","family":"Kiwan","sequence":"additional","affiliation":[{"name":"Department of General Surgery, St. Elizabeth\u2019s Hospital , Youngstown, OH ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benson","family":"Li","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Summa Health Systems , Akron, OH ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Autumn","family":"Pak","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Summa Health Systems , Akron, OH ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Keisling","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Akron Children\u2019s Hospital , Akron, OH ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin T","family":"Huntington","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Akron Children\u2019s Hospital , Akron, OH ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"2026071406503521100_ref1","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1002\/jso.70153","article-title":"Comparison of presentation and management in skeletal and extraskeletal Ewing sarcoma in children","volume":"133","author":"Chidiac","year":"2026","journal-title":"J Surg Oncol"},{"key":"2026071406503521100_ref2","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1148\/rg.210226","article-title":"Extraskeletal Ewing sarcoma from head to toe: multimodality imaging review","volume":"42","author":"Wright","year":"2022","journal-title":"Radiographics"},{"key":"2026071406503521100_ref3","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1056\/NEJMra2028910","article-title":"Ewing\u2019s sarcoma","volume":"384","author":"Riggi","year":"2021","journal-title":"N Engl J Med"},{"key":"2026071406503521100_ref4","doi-asserted-by":"publisher","first-page":"354","DOI":"10.3892\/ol.2021.12615","article-title":"Extraskeletal Ewing sarcoma: diagnosis, management and prognosis","volume":"21","author":"Abboud","year":"2021","journal-title":"Oncol Lett"},{"key":"2026071406503521100_ref5","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1097\/PAS.0000000000002163","article-title":"Gastrointestinal Ewing sarcoma: a clinicopathological and molecular genetic analysis of 25 cases","volume":"48","author":"Yin","year":"2024","journal-title":"Am J Surg Pathol"},{"key":"2026071406503521100_ref6","doi-asserted-by":"publisher","first-page":"207","DOI":"10.3892\/ol.2011.246","article-title":"Gastric Ewing sarcoma\/primitive neuroectodermal tumor: a case report","volume":"2","author":"Inoue","year":"2011","journal-title":"Oncol Lett"},{"key":"2026071406503521100_ref7","doi-asserted-by":"publisher","first-page":"300060520986681","DOI":"10.1177\/0300060520986681","article-title":"Primary gastric Ewing sarcoma\/primitive neuroectodermal tumor","volume":"49","author":"Ye","year":"2021","journal-title":"J Int Med Res"},{"key":"2026071406503521100_ref8","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1007\/s005350070009","article-title":"Ewing's sarcoma\/peripheral primitive neuroectodermal tumor (pPNET) arising in the omentum as a multilocular cyst with intracystic hemorrhage","volume":"35","author":"Tanida","year":"2000","journal-title":"J Gastroenterol"},{"key":"2026071406503521100_ref9","doi-asserted-by":"publisher","first-page":"258","DOI":"10.5230\/jgc.2012.12.4.258","article-title":"Ewing's sarcoma of the stomach; 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