{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T18:39:42Z","timestamp":1784745582733,"version":"3.55.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Posterior mediastinal cysts are rare lesions accounting for ~5%\u201310% of mediastinal cysts. Most are bronchogenic, enteric, or neurogenic in origin; however, M\u00fcllerian cysts have recently been recognized as a distinct entity thought to arise from displaced M\u00fcllerian duct tissue. Mayer-Rokitansky-K\u00fcster-Hauser (MRKH) syndrome results from incomplete development of M\u00fcllerian ducts and is characterized by congenital absence of the uterus and upper vagina. A shared embryological origin suggests a possible association between MRKH syndrome and mediastinal M\u00fcllerian cysts. We report the first known case of a posterior mediastinal cyst in a patient with MRKH syndrome type II treated successfully with uniportal video-assisted thoracoscopic surgery. We discuss the clinical presentation, histopathological findings, surgical management, and potential embryological link between these conditions.<\/jats:p>","DOI":"10.1093\/jscr\/rjag609","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:55:02Z","timestamp":1784742902000},"source":"Crossref","is-referenced-by-count":0,"title":["Posterior mediastinal M\u00fcllerian cyst in a patient with Mayer-Rokitansky-K\u00fcster-Hauser syndrome: a case report"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4131-9179","authenticated-orcid":false,"given":"Oleg","family":"Aleksandrov","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, University College London Hospitals NHS Foundation Trust , 250 Euston Road, London NW1 2PG ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2492-799X","authenticated-orcid":false,"given":"Davide","family":"Patrini","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, University College London Hospitals NHS Foundation Trust , 250 Euston Road, London NW1 2PG ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Mario","family":"De Luca","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, University College London Hospitals NHS Foundation Trust , 250 Euston Road, London NW1 2PG ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, University College London Hospitals NHS Foundation Trust , 250 Euston Road, London NW1 2PG ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Gkikas","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, University College London Hospitals NHS Foundation Trust , 250 Euston Road, London NW1 2PG ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amali","family":"Jayathilaka","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, University College London Hospitals NHS Foundation Trust , 250 Euston Road, London NW1 2PG ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"2026072213545921100_ref1","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1111\/cge.12883","article-title":"Genetics of Mayer-Rokitansky-K\u00fcster-Hauser (MRKH) syndrome","volume":"91","author":"Fontana","year":"2017","journal-title":"Clin Genet"},{"key":"2026072213545921100_ref2","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1093\/humrep\/dei381","article-title":"Clinical aspects of Mayer-Rokitansky-Kuester-Hauser syndrome: recommendations for clinical diagnosis and staging","volume":"21","author":"Oppelt","year":"2006","journal-title":"Hum Reprod"},{"key":"2026072213545921100_ref3","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1378\/chest.124.1.125","article-title":"Clinical spectrum of mediastinal cysts","volume":"124","author":"Takeda","year":"2003","journal-title":"Chest"},{"key":"2026072213545921100_ref4","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1007\/s00428-004-1087-0","article-title":"Ciliated cyst of probable mullerian origin arising in the posterior mediastinum","volume":"446","author":"Hattori","year":"2005","journal-title":"Virchows Arch"},{"key":"2026072213545921100_ref5","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/s004040050225","article-title":"The Mayer-Rokitansky-K\u00fcster syndrome. An analysis of its morphology and embryology. Part II: embryology","volume":"262","author":"Ludwig","year":"1998","journal-title":"Arch Gynecol Obstet"},{"key":"2026072213545921100_ref6","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1186\/s13023-020-01491-9","article-title":"Mayer-Rokitansky-K\u00fcster-Hauser (MRKH) syndrome: a comprehensive update","volume":"15","author":"Herlin","year":"2020","journal-title":"Orphanet J Rare Dis"},{"key":"2026072213545921100_ref7","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.anndiagpath.2006.12.011","article-title":"Cysts of the posterior mediastinum showing m\u00fcllerian differentiation (Hattori\u2019s cysts)","volume":"11","author":"Thomas-de-Montr\u00e9ville","year":"2007","journal-title":"Ann Diagn Pathol"},{"key":"2026072213545921100_ref8","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.ejcts.2007.09.036","article-title":"A ciliated cyst in the posterior mediastinum compatible with a paravertebral Mullerian cyst","volume":"33","author":"Businger","year":"2008","journal-title":"Eur J Cardiothorac Surg"},{"key":"2026072213545921100_ref9","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1097\/PGP.0b013e3181e3640a","article-title":"Pathogenesis of mediastinal paravertebral M\u00fcllerian cysts of Hattori: developmental endosalpingiosis-m\u00fcllerianosis","volume":"29","author":"Batt","year":"2010","journal-title":"Int J Gynecol Pathol"},{"key":"2026072213545921100_ref10","first-page":"8","article-title":"Mullerian cysts of the posterior mediastinum: report of two cases and review of the literature","volume":"5","author":"Simmons","year":"2013","journal-title":"J Thorac Dis"},{"key":"2026072213545921100_ref11","first-page":"e229","article-title":"Mediastinal Mullerian cyst: clues to the pathogenesis of thoracic foregut cysts as developmental vagaries","volume":"110","author":"Farmer","year":"2020","journal-title":"Ann Thorac Surg"},{"key":"2026072213545921100_ref12","doi-asserted-by":"publisher","first-page":"1431454","DOI":"10.3389\/fonc.2024.1431454","article-title":"Mullerian cyst of mediastinum: report of two cases","volume":"14","author":"Abulizi","year":"2024","journal-title":"Front Oncol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/7\/rjag609\/69802521\/rjag609.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/7\/rjag609\/69802521\/rjag609.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:55:03Z","timestamp":1784742903000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag609\/8740024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7,4]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag609","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,7]]},"published":{"date-parts":[[2026,7]]},"article-number":"rjag609"}}