{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:59:30Z","timestamp":1785427170378,"version":"3.56.0"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The finding of an adrenal mass in a patient with a history of extra-adrenal malignancy represents a diagnostic dilemma, in which metastasis is usually the primary suspicion. Pure adrenal lipomas are extremely rare benign tumors (&amp;lt;5% of adrenal neoplasms) that can coexist with other malignancies. We present the case of a 66-year-old female with a history of infiltrating ductal carcinoma of the breast treated in 2023. During her surveillance protocol, a computed tomography scan revealed a right renal mass and an ipsilateral adrenal lesion with fat density. Given the clinical suspicion of a second primary renal tumor and possible metastatic activity, a right radical nephrectomy was performed. Histopathological analysis confirmed a high-grade clear cell renal cell carcinoma (Grade 4, sarcomatoid features) pT1a, and a synchronous pure adrenal lipoma, definitively ruling out metastasis and myelolipoma. This case underscores the importance of an accurate radiological-pathological correlation to avoid diagnostic bias in complex oncological patients.<\/jats:p>","DOI":"10.1093\/jscr\/rjag647","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T11:34:34Z","timestamp":1784028874000},"source":"Crossref","is-referenced-by-count":0,"title":["Synchronous pure adrenal lipoma and clear cell renal cell carcinoma with sarcomatoid differentiation in a patient with a history of breast cancer: a case report"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7754-4629","authenticated-orcid":false,"given":"Luis Jes\u00fas","family":"Garza","sequence":"first","affiliation":[{"name":"Department of General Surgery, Hospital de Especialidades No. 1, Centro M\u00e9dico Nacional \u201cIgnacio Garc\u00eda T\u00e9llez\u201d, Instituto Mexicano del Seguro Social , M\u00e9rida, Yucat\u00e1n 97155 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4490-260X","authenticated-orcid":false,"given":"Jos\u00e9 Rodrigo Alc\u00e1ntara","family":"Dzib","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital de Especialidades No. 1, Centro M\u00e9dico Nacional \u201cIgnacio Garc\u00eda T\u00e9llez\u201d, Instituto Mexicano del Seguro Social , M\u00e9rida, Yucat\u00e1n 97155 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3116-7227","authenticated-orcid":false,"given":"Luis Ra\u00fal","family":"Miramontes","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital de Especialidades No. 1, Centro M\u00e9dico Nacional \u201cIgnacio Garc\u00eda T\u00e9llez\u201d, Instituto Mexicano del Seguro Social , M\u00e9rida, Yucat\u00e1n 97155 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"2026073010590373600_ref1","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1093\/ejendo\/lvad066","article-title":"European Society of Endocrinology clinical practice guidelines on the management of adrenal incidentalomas, in collaboration with the European Network for the Study of Adrenal Tumors","volume":"189","author":"Fassnacht","year":"2023","journal-title":"Eur J Endocrinol"},{"key":"2026073010590373600_ref2","doi-asserted-by":"crossref","first-page":"978730","DOI":"10.3389\/fendo.2022.978730","article-title":"Distinguishing between metastatic and benign adrenal masses in patients with extra-adrenal malignancies: a retrospective study","volume":"13","author":"Li","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2026073010590373600_ref3","author":"Cingam","year":"2026"},{"key":"2026073010590373600_ref4","first-page":"342","article-title":"Adrenal lipoma: a case report and literature review","volume":"37","author":"Kagda","year":"2020","journal-title":"Pan Afr Med J"},{"key":"2026073010590373600_ref5","first-page":"44","article-title":"Giant adrenal myelolipomas: a literature review of case reports (1981\u20132023)","volume":"13","author":"Guo","year":"2024","journal-title":"J Clin Med"},{"key":"2026073010590373600_ref6","first-page":"1050","article-title":"French AFU cancer committee guidelines - update 2024-2026: assessment of an adrenal incidentaloma and oncological management","volume":"34","author":"Robin","year":"2024","journal-title":"Prog Urol"},{"key":"2026073010590373600_ref7","volume-title":"StatPearls [Internet]"},{"key":"2026073010590373600_ref8","doi-asserted-by":"crossref","first-page":"e2510306122","DOI":"10.1073\/pnas.2510306122","article-title":"Adrenal lipoma formation via PI(3,4,5)P3\/AKT-dependent transdifferentiation of adrenocortical cells into adipocytes","volume":"122","author":"Yanai","year":"2025","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/7\/rjag647\/70389582\/rjag647.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/7\/rjag647\/70389582\/rjag647.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:59:11Z","timestamp":1785423551000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag647\/8747549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7,4]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag647","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,7]]},"published":{"date-parts":[[2026,7]]},"article-number":"rjag647"}}