{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:24:01Z","timestamp":1787318641607,"version":"build-2736575974"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Goiter is a common benign condition that typically presents with a sensation of pressure in the neck. In a slowly growing disease, the pressure symptom may be confused with another disease causing airway obstruction, and the diagnosis becomes even more difficult if the enlarged thyroid gland is located behind the sternum and not just in the neck. We describe a case of a patient who suffered from treatment-resistant obstructive airway symptoms for years, experienced several upper and lower respiratory tract infections, and underwent repeated investigations for asthma. Eventually, a large retrosternal goiter was identified as the cause of the symptoms, which was treated surgically.<\/jats:p>","DOI":"10.1093\/jscr\/rjag674","type":"journal-article","created":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T11:32:51Z","timestamp":1786707171000},"source":"Crossref","is-referenced-by-count":0,"title":["When asthma medication fails: a large retrosternal goiter as the underlying cause of airway obstruction"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1266-9604","authenticated-orcid":false,"given":"Kimmo","family":"Kuosmanen","sequence":"first","affiliation":[{"name":"Department of Surgery, North Karelia Central Hospital , Tikkam\u00e4entie 16, Joensuu 80210 ,","place":["Finland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari","family":"Heikkinen","sequence":"additional","affiliation":[{"name":"Department of Surgery, North Karelia Central Hospital , Tikkam\u00e4entie 16, Joensuu 80210 ,","place":["Finland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Govenius","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuopio University Hospital , Puijonlaaksontie 2, Kuopio 70210 ,","place":["Finland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ville","family":"V\u00e4nni","sequence":"additional","affiliation":[{"name":"Department of Surgery, North Karelia Central Hospital , Tikkam\u00e4entie 16, Joensuu 80210 ,","place":["Finland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"2026082108275280300_ref1","article-title":"Struuma (suurentunut kilpirauhanen)","author":"Pelttari","year":"2024","journal-title":"L\u00e4\u00e4k\u00e4rikirja Duodecim [Internet]"},{"key":"2026082108275280300_ref2","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.3892\/ol.2015.3464","article-title":"Acute airway obstruction due to benign asymptomatic nodular goiter in the cervical region: a case report","volume":"10","author":"Ito","year":"2015","journal-title":"Oncol Lett"},{"key":"2026082108275280300_ref3","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1017\/S0022215106003045","article-title":"Management of life-threatening airway obstruction caused by benign thyroid disease","volume":"120","author":"Kadhim","year":"2006","journal-title":"J Laryngol Otol"},{"key":"2026082108275280300_ref4","doi-asserted-by":"crossref","first-page":"A6225","DOI":"10.1164\/ajrccm.2025.211.Abstracts.A6225","article-title":"Asthma or airway obstruction? A case of substernal goiter presenting in pregnancy","volume":"211","author":"Nakdali","year":"2025","journal-title":"Am J Respir Crit Care Med"},{"key":"2026082108275280300_ref5","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/j.otohns.2005.01.039","article-title":"The surgical approach to retrosternal goiters: the role of computerized tomography","volume":"132","author":"Grainger","year":"2005","journal-title":"Otolaryngol Head Neck Surg"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/8\/rjag674\/70752918\/rjag674.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/8\/rjag674\/70752918\/rjag674.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:27:56Z","timestamp":1787315276000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag674\/8767705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":5,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8,4]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag674","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,8]]},"published":{"date-parts":[[2026,8]]},"article-number":"rjag674"}}