{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T01:27:07Z","timestamp":1786757227611,"version":"build-2736575974"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T00:00:00Z","timestamp":1786752000000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Gynecomastia (GM) is a benign condition involving glandular proliferation within male breast tissue. Atypical ductal hyperplasia (ADH) is considered a high-risk lesion due to its association with an increased risk of breast cancer; however, the literature remains sparse regarding the male population with underlying ADH. ADH in the setting of GM. Currently, the reported incidence of ADH with GM ranges from 0.4% to 4.5%. Here, we present a case of a male patient with recurrent ADH after a previous excision for bilateral ADH that was upstaged to ductal carcinoma in situ (DCIS) after definitive surgery for the recurrent ADH. The ADH and DCIS were successfully excised via central lumpectomy. A brief literature review on its incidence and treatment within the male population was also conducted. This case highlights the rarity of ADH and DCIS in men, as well as their recurrence following nipple-sparing mastectomy.<\/jats:p>","DOI":"10.1093\/jscr\/rjag713","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T11:21:57Z","timestamp":1785151317000},"source":"Crossref","is-referenced-by-count":0,"title":["Recurrent atypical ductal hyperplasia in the setting of gynecomastia in a male patient: a unique finding and brief literature review"],"prefix":"10.1093","volume":"2026","author":[{"given":"Amanda Rose","family":"Camarda","sequence":"first","affiliation":[{"name":"St. George\u2019s University School of Medicine , True Blue, St. George ,","place":["Grenada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Marcucci","sequence":"additional","affiliation":[{"name":"Department of Surgery, Jersey Shore University Medical Center , Neptune, NJ 07756 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William P","family":"Frampton","sequence":"additional","affiliation":[{"name":"Department of Pathology, Jersey Shore University Medical Center , Neptune, NJ 07756 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshani","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Surgery, Jersey Shore University Medical Center , Neptune, NJ 07756 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,14]]},"reference":[{"key":"2026081420461113100_ref1","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1056\/NEJM199302183280708","article-title":"Gynecomastia","volume":"328","author":"Braunstein","year":"1993","journal-title":"N Engl J Med"},{"key":"2026081420461113100_ref2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10549-018-05117-4","article-title":"Atypical ductal hyperplasia in men with gynecomastia: what is their breast cancer risk?","volume":"175","author":"Coopey","year":"2019","journal-title":"Breast Cancer Res Treat"},{"key":"2026081420461113100_ref3","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.breast.2005.04.010","article-title":"Bilateral atypical ductal hyperplasia, an incidental finding in gynaecomastia\u2014case report and literature review","volume":"14","author":"Prasad","year":"2005","journal-title":"Breast"},{"key":"2026081420461113100_ref4","first-page":"270","article-title":"Atypia on breast core needle biopsies: reproducibility and significance","volume":"39","author":"Darvishian","year":"2009","journal-title":"Ann Clin Lab Sci"},{"key":"2026081420461113100_ref5","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1097\/MAJ.0b013e318234cc67","article-title":"Atypical hyperplasia on core biopsy: is further surgery needed?","volume":"344","author":"Polat","year":"2012","journal-title":"Am J Med Sci"},{"key":"2026081420461113100_ref6","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1111\/andr.12636","article-title":"EAA clinical practice guidelines\u2014gynecomastia evaluation and management","volume":"7","author":"Kanakis","year":"2019","journal-title":"Andrology"},{"key":"2026081420461113100_ref7","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1677\/erc.0.0060315","article-title":"Aromatase and gynecomastia","volume":"6","author":"Braunstein","year":"1999","journal-title":"Endocr Relat Cancer"},{"key":"2026081420461113100_ref8","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1016\/S0031-3955(16)37016-X","article-title":"Adolescent gynecomastia. Differential diagnosis and management","volume":"37","author":"Mahoney","year":"1990","journal-title":"Pediatr Clin North Am"},{"key":"2026081420461113100_ref9","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1056\/NEJMsr1407164","article-title":"Atypical hyperplasia of the breast\u2014risk assessment and management options","volume":"372","author":"Hartmann","year":"2015","journal-title":"N Engl J Med"},{"key":"2026081420461113100_ref10","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1097\/SAP.0b013e3182920aed","article-title":"Pathological findings in gynecomastia","volume":"74","author":"Lapid","year":"2015","journal-title":"Ann Plast Surg"},{"key":"2026081420461113100_ref11","doi-asserted-by":"publisher","first-page":"1760","DOI":"10.1016\/j.bjps.2014.06.009","article-title":"Six factors justify the pathologic analysis of subcutaneous mastectomy specimens in patients with gynaecomastia","volume":"67","author":"Agostini","year":"2014","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"2026081420461113100_ref12","doi-asserted-by":"publisher","first-page":"260","DOI":"10.4048\/jbc.2024.0077","article-title":"Safety of atypical ductal hyperplasia at the nipple margin in nipple-sparing mastectomy","volume":"27","author":"Zhu","year":"2024","journal-title":"J Breast Cancer"},{"key":"2026081420461113100_ref13","doi-asserted-by":"publisher","first-page":"10528","DOI":"10.1200\/JCO.2023.41.16_suppl.10528","article-title":"Breast cancer: global patterns of incidence, mortality, and trends","volume":"41","author":"Sedeta","year":"2023","journal-title":"J Clin Oncol"},{"key":"2026081420461113100_ref14","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/s10549-022-06689-y","article-title":"Ductal carcinoma in situ of the male breast: clinical radiological features and management in a cancer referral center","volume":"196","author":"Nicosia","year":"2022","journal-title":"Breast Cancer Res Treat"},{"key":"2026081420461113100_ref15","doi-asserted-by":"publisher","first-page":"103","DOI":"10.3233\/BD-160223","article-title":"Incidental unilateral and bilateral ductal carcinoma in situ encountered in the surgical management of young male gynecomastia","volume":"36","author":"Shirah","year":"2016","journal-title":"Breast Dis"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/8\/rjag713\/70653754\/rjag713.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/8\/rjag713\/70653754\/rjag713.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T00:46:16Z","timestamp":1786754776000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag713\/8761900"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8,4]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag713","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,8]]},"published":{"date-parts":[[2026,8]]},"article-number":"rjag713"}}