{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:11:49Z","timestamp":1790035909963,"version":"4.0.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Amyand\u2019s hernia, defined as the presence of the vermiform appendix within an inguinal hernia sac, is an uncommon surgical finding. The association with appendiceal neoplasms is exceedingly rare, particularly in the absence of inflammatory signs. We report the case of a 71-year-old male with a longstanding right inguinoscrotal hernia presenting with progressive discomfort. An open hernia repair revealed the cecum and a macroscopically non-inflamed appendix within the hernia sac. Appendectomy was performed, followed by sutureless mesh hernioplasty. Histopathological examination unexpectedly demonstrated a low-grade appendiceal mucinous neoplasm with free resection margins. The postoperative course was uneventful, the patient remained asymptomatic at follow-up. This case suggests that even a clinically silent appendix within an Amyand\u2019s hernia may harbor occult neoplastic pathology. Appendectomy should therefore be considered in adult patients to avoid missed diagnoses with potential oncological implications.<\/jats:p>","DOI":"10.1093\/jscr\/rjag796","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:16:43Z","timestamp":1788520603000},"source":"Crossref","is-referenced-by-count":0,"title":["Low-grade appendiceal mucinous neoplasm in an uncomplicated Amyand\u2019s hernia: a case report"],"prefix":"10.1093","volume":"2026","author":[{"given":"Pietro","family":"Calabrese","sequence":"first","affiliation":[{"name":"Surgical Unit Cobellis Clinical Hospital , Vallo della Lucania ,","place":["Italy"]},{"name":"Department of General Surgery, Transplantation and Gastroenterology, Federico II University Hospital , Naples ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Cobellis","sequence":"additional","affiliation":[{"name":"Surgical Unit Cobellis Clinical Hospital , Vallo della Lucania ,","place":["Italy"]},{"name":"University of Padua , Padua ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Spagnuolo","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Transplantation and Gastroenterology, Federico II University Hospital , Naples ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Cobellis","sequence":"additional","affiliation":[{"name":"Surgical Unit Cobellis Clinical Hospital , Vallo della Lucania ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"2026092119535834000_ref1","first-page":"329","article-title":"Of an inguinal rupture, with a pin in the appendix caeci, incrusted with stone; and some observations on wounds in the guts","volume":"39","author":"Amyand","year":"1735","journal-title":"Philos Trans R Soc Lond"},{"key":"2026092119535834000_ref2","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1007\/s10029-008-0331-y","article-title":"Amyand hernia: a classification to improve management","volume":"12","author":"Losanoff","year":"2008","journal-title":"Hernia"},{"key":"2026092119535834000_ref3","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1097\/PAS.0000000000000535","article-title":"A consensus for classification and pathologic reporting of pseudomyxoma peritonei and associated appendiceal neoplasia","volume":"40","author":"Carr","year":"2016","journal-title":"Am J Surg Pathol"},{"key":"2026092119535834000_ref4","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1007\/s10029-009-0552-8","article-title":"Amyand\u2019s hernia with adenocarcinoid tumor","volume":"14","author":"Wu","year":"2010","journal-title":"Hernia"},{"key":"2026092119535834000_ref5","doi-asserted-by":"publisher","first-page":"bcr2017219428","DOI":"10.1136\/bcr-2017-219428","article-title":"Amyand\u2019s hernia containing an appendiceal goblet cell carcinoid tumour","volume":"2017","author":"Yahya","year":"2017","journal-title":"BMJ Case Rep"},{"key":"2026092119535834000_ref6","doi-asserted-by":"publisher","first-page":"105716","DOI":"10.1016\/j.ijscr.2021.105716","article-title":"Amyand\u2019s hernia with appendiceal adenocarcinoma","volume":"81","author":"Fiordaliso","year":"2021","journal-title":"Int J Surg Case Rep"},{"key":"2026092119535834000_ref7","doi-asserted-by":"publisher","first-page":"514","DOI":"10.18999\/nagjms.86.3.514","article-title":"Appendiceal adenocarcinoma associated with Amyand\u2019s hernia","volume":"86","author":"Momota","year":"2024","journal-title":"Nagoya J Med Sci"},{"key":"2026092119535834000_ref8","doi-asserted-by":"publisher","first-page":"e2022273","DOI":"10.23750\/abm.v93iS1.13322","article-title":"Amyand\u2019s hernia: which oncologic risk can be hidden in the sac?","volume":"93","author":"Montali","year":"2022","journal-title":"Acta Biomed"},{"key":"2026092119535834000_ref9","doi-asserted-by":"publisher","first-page":"183","DOI":"10.3393\/ac.2021.00430.0061","article-title":"A rare presentation of low-grade appendiceal mucinous neoplasm within an Amyand\u2019s hernia","volume":"39","author":"Saim","year":"2023","journal-title":"Ann Coloproctol"},{"key":"2026092119535834000_ref10","doi-asserted-by":"publisher","first-page":"e65801","DOI":"10.7759\/cureus.65801","article-title":"Complicated appendicitis associated with appendiceal mucinous neoplasm within Amyand\u2019s hernia","volume":"16","author":"Navarro-Casta\u00f1eda","year":"2024","journal-title":"Cureus"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/9\/rjag796\/71292919\/rjag796.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/9\/rjag796\/71292919\/rjag796.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:54:04Z","timestamp":1790034844000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag796\/8825417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,8,31]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag796","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,8,31]]},"article-number":"rjag796"}}