{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:07:35Z","timestamp":1790726855040,"version":"4.1.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Salvage laryngopharyngectomy in patients with a prior history of chemoradiation and surgery constitutes a substantial reconstructive challenge. Functional recovery is often limited by compromised vascular integrity combined with loss of pharyngeal mucosa, contributing to high rates of post-operative complications. We present a patient with squamous cell carcinoma of the esophagus, previously managed with chemoradiation and salvage esophagectomy with pharyngogastric anastomosis. She developed a second recurrence involving the pyriform sinus adjacent to the neoesophagus, requiring salvage laryngopharyngectomy and circumferential free flap reconstruction. An anterolateral thigh microvascular free flap was anastomosed to the gastric conduit. Despite significant risk factors of anatomic defect and hypovascularity, the patient successfully regained oral intake. This case demonstrates that favorable functional outcomes are possible in medically complex patients undergoing salvage reconstruction.<\/jats:p>","DOI":"10.1093\/jscr\/rjag852","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:24:23Z","timestamp":1789673063000},"source":"Crossref","is-referenced-by-count":0,"title":["Oral intake recovery following salvage laryngectomy with circumferential free flap reconstruction in a patient with prior pharyngogastric anastomosis and chemoradiation"],"prefix":"10.1093","volume":"2026","author":[{"given":"Chloe E","family":"Coulter","sequence":"first","affiliation":[{"name":"University of Mississippi School of Medicine , 2500 N State Street, Jackson, MS 39216 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel J","family":"Hopper","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Mississippi Medical Center , 2500 N State Street, 5 East, Jackson, MS 39216 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gina D","family":"Jefferson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Mississippi Medical Center , 2500 N State Street, 5 East, Jackson, MS 39216 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"2026092919214377600_ref1","doi-asserted-by":"publisher","first-page":"2073","DOI":"10.1002\/cncr.20974","article-title":"Postoperative complications of salvage total laryngectomy","volume":"103","author":"Ganly","year":"2005","journal-title":"Cancer"},{"key":"2026092919214377600_ref2","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.otc.2022.12.002","article-title":"Salvage 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of surgical outcomes and postoperative complications based on free flap selection for reconstructing primary or recurrent locally advanced laryngeal-hypopharyngeal tumours","volume":"46","author":"De Luca","year":"2026","journal-title":"Acta Otorrinolaringol Ital"},{"key":"2026092919214377600_ref6","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/s12070-020-01806-z","article-title":"Role of total laryngopharyngoesophagectomy with gastric pull up in the management of locally advanced hypopharyngeal cancers","volume":"74","author":"Devaraja","year":"2022","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"2026092919214377600_ref7","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/1471-2407-2-13","article-title":"Jejunum free flap in hypopharynx reconstruction: case series","volume":"2","author":"Benazzo","year":"2002","journal-title":"BMC 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