{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T07:28:19Z","timestamp":1793777299795,"version":"4.6.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Although congenital pulmonary airway malformation (CPAM) is usually diagnosed during prenatal screening, delayed presentation may increase diagnostic uncertainty and operative complexity. We report, to our knowledge, the first case of CPAM diagnosed and surgically managed in Syria in a 4-month-old infant presenting with a 1-month history of dyspnea, fever, and poor feeding in the absence of routine prenatal screening. Initial chest radiography, although technically limited, demonstrated a rounded opacity in the right hemithorax, while non-contrast chest computed tomography (CT) revealed multicystic lesions with a hyperattenuating intralesional component, raising suspicion for secondary infection or pleuropulmonary blastoma (PPB). The patient underwent right upper and middle bilobectomy, and histopathological examination confirmed CPAM and excluded PPB. This case highlights the complementary roles of postnatal CT, surgery, and histopathology in confirming CPAM and excluding PPB, particularly when delayed presentation increases operative complexity.<\/jats:p>","DOI":"10.1093\/jscr\/rjag924","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T18:55:42Z","timestamp":1792436142000},"source":"Crossref","is-referenced-by-count":0,"title":["Delayed diagnosis of congenital pulmonary airway malformation in an infant: diagnostic challenges and surgical implications"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3735-7400","authenticated-orcid":false,"given":"Nour","family":"Srewell","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, Al-Mouwasat University Hospital , Omar Bin Abdul Aziz Street, Mezzeh, Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youssef","family":"Chouman","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children University Hospital , Al-Mouwasat Street, Mezzeh, Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yamama","family":"Sharief","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children University Hospital , Al-Mouwasat Street, Mezzeh, Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Baraa","family":"Meqdad","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children University Hospital , Al-Mouwasat Street, Mezzeh, Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mira","family":"Hamzeh Rafea","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children University Hospital , Al-Mouwasat Street, Mezzeh, Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Alsalama","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children University Hospital , Al-Mouwasat Street, Mezzeh, Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bushra","family":"Alsahan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children University Hospital , Al-Mouwasat Street, Mezzeh, Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammd","family":"Abdulkader","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children University Hospital , Al-Mouwasat Street, Mezzeh, Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sawssan","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children University Hospital , Al-Mouwasat Street, Mezzeh, Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,19]]},"reference":[{"key":"2026110401431543800_ref1","doi-asserted-by":"publisher","first-page":"638","DOI":"10.3390\/children11060638","article-title":"Congenital lung malformations: a pictorial review of imaging findings and a practical guide for diagnosis","volume":"11","author":"Cancemi","year":"2024","journal-title":"Children (Basel)"},{"key":"2026110401431543800_ref2","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.21037\/tp-20-133","article-title":"Narrative review of congenital lung lesions","volume":"10","author":"Kunisaki","year":"2021","journal-title":"Transl Pediatr"},{"key":"2026110401431543800_ref3","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1038\/s41572-023-00470-1","article-title":"Congenital lung malformations","volume":"9","author":"Pederiva","year":"2023","journal-title":"Nat Rev Dis Primers"},{"key":"2026110401431543800_ref4","doi-asserted-by":"publisher","first-page":"547","DOI":"10.20344\/amp.23967","article-title":"Challenges with congenital lung cysts: when to consider DICER1 testing? A narrative review","volume":"39","author":"Rocha","year":"2026","journal-title":"Acta Med Port"},{"key":"2026110401431543800_ref5","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.jpedsurg.2015.10.019","article-title":"Can congenital pulmonary airway malformation be distinguished from type I pleuropulmonary blastoma based on clinical and radiological features?","volume":"51","author":"Feinberg","year":"2016","journal-title":"J Pediatr Surg"},{"key":"2026110401431543800_ref6","doi-asserted-by":"publisher","first-page":"86","DOI":"10.3390\/children6080086","article-title":"Current management of pleuropulmonary blastoma: a surgical perspective","volume":"6","author":"Knight","year":"2019","journal-title":"Children (Basel)"},{"key":"2026110401431543800_ref7","doi-asserted-by":"publisher","first-page":"110096","DOI":"10.1016\/j.ijscr.2024.110096","article-title":"Clinical and histopathological spectrum of congenital pulmonary airway malformations: a case series","volume":"122","author":"Khan","year":"2024","journal-title":"Int J Surg Case Rep"},{"key":"2026110401431543800_ref8","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int J Surg"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/10\/rjag924\/72116188\/rjag924.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/10\/rjag924\/72116188\/rjag924.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T06:43:23Z","timestamp":1793774603000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag924\/8943706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":8,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag924","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,10]]},"published":{"date-parts":[[2026,10]]},"article-number":"rjag924"}}