{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T18:40:45Z","timestamp":1792435245117,"version":"4.5.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Gastric schwannomas are rare, benign mesenchymal tumours that closely mimic gastrointestinal stromal tumours (GISTs) on imaging, despite fundamentally different biological behaviour. We report a 74-year-old man with a background of proctocolectomy for rectal cancer, found incidentally to have a 5\u00a0cm exophytic gastric mass on surveillance gastroscopy. Endoscopic ultrasound-guided fine needle aspiration favoured schwannoma, and the patient underwent an uncomplicated laparoscopic gastric wedge resection. Histopathology confirmed gastric schwannoma with clear margins and no nodal involvement; immunohistochemistry was positive for S100 calcium-binding protein (S100)\/SRY-box transcription factor 10 (SOX10) and negative for discovered on GIST-1 (DOG1)\/CD117 (c-KIT)\/smooth muscle actin (SMA)\/desmin, excluding GIST. He recovered well and was discharged after 2 days, with a conservative surveillance endoscopy plan (6 months, then annually for 5 years) agreed at multidisciplinary team meeting. This case underscores the essential role of immunohistochemistry in distinguishing gastric schwannoma from GIST, and highlights the absence of a consensus surveillance protocol following resection.<\/jats:p>","DOI":"10.1093\/jscr\/rjag927","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T18:18:51Z","timestamp":1792433931000},"source":"Crossref","is-referenced-by-count":0,"title":["Gastric schwannoma: a case report"],"prefix":"10.1093","volume":"2026","author":[{"given":"Mohamed Tariq","family":"Haniff","sequence":"first","affiliation":[{"name":"Department of Upper Gastrointestinal Surgery, Concord Repatriation General Hospital , Hospital Road, Concord, NSW 2139 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Tse","sequence":"additional","affiliation":[{"name":"Department of Upper Gastrointestinal Surgery, Concord Repatriation General Hospital , Hospital Road, Concord, NSW 2139 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Becerril-Martinez","sequence":"additional","affiliation":[{"name":"Department of Upper Gastrointestinal Surgery, Concord Repatriation General Hospital , Hospital Road, Concord, NSW 2139 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,19]]},"reference":[{"key":"2026101914184820100_ref1","first-page":"436","article-title":"Gastrointestinal tract spindle cell lesions\u2014just a GIST? Diagnostic pathology considerations","volume":"31","author":"Voltaggio","year":"2014","journal-title":"Semin Diagn Pathol"},{"key":"2026101914184820100_ref2","first-page":"S184","article-title":"Gastrointestinal schwannomas: a rare but important differential diagnosis of mesenchymal tumors of gastrointestinal tract","volume":"7","author":"Melo","year":"2018","journal-title":"Gland Surg"},{"key":"2026101914184820100_ref3","first-page":"47","article-title":"Preoperative differentiation of gastric schwannomas and gastrointestinal stromal tumors based on computed tomography: a retrospective multicenter observational study","volume":"15","author":"Yang","year":"2024","journal-title":"Insights Imaging"},{"key":"2026101914184820100_ref4","doi-asserted-by":"publisher","first-page":"1003895","DOI":"10.3389\/fonc.2022.1003895","article-title":"Clinicopathological characteristics of gastrointestinal schwannomas: a retrospective analysis of 78 cases","volume":"12","author":"Wang","year":"2022","journal-title":"Front Oncol"},{"key":"2026101914184820100_ref5","volume":"3","author":"Haase","year":"2022"},{"key":"2026101914184820100_ref6","doi-asserted-by":"publisher","first-page":"rjae793","DOI":"10.1093\/jscr\/rjae793","article-title":"Differential diagnosis of submucosal gastric tumors: gastric schwannomas misdiagnosed as GISTs","volume":"2024","author":"Elmi","year":"2024","journal-title":"J Surg Case Rep"},{"key":"2026101914184820100_ref7","first-page":"1753731","article-title":"Gastric schwannoma: a case report and review of the literature for gastric submucosal masses distinction","volume":"2017","author":"Karabulut","year":"2017","journal-title":"Case Rep Surg"},{"key":"2026101914184820100_ref8","doi-asserted-by":"publisher","first-page":"e7175","DOI":"10.1097\/MD.0000000000007175","article-title":"Role of endoscopic ultrasound and endoscopic resection for the treatment of gastric schwannoma","volume":"96","author":"Xu","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"2026101914184820100_ref9","doi-asserted-by":"publisher","first-page":"2325","DOI":"10.1002\/cncr.28669","article-title":"Risk factors for gastrointestinal stromal tumor recurrence in patients treated with adjuvant imatinib","volume":"120","author":"Joensuu","year":"2014","journal-title":"Cancer"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/10\/rjag927\/72115777\/rjag927.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2026\/10\/rjag927\/72115777\/rjag927.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T18:18:52Z","timestamp":1792433932000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjag927\/8943660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjag927","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,10]]},"published":{"date-parts":[[2026,10]]},"article-number":"rjag927"}}