{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:24:36Z","timestamp":1761845076662,"version":"3.41.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T00:00:00Z","timestamp":1567036800000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Malignant triton tumor (MTT) is a rare subtype of malignant peripheral nerve sheath tumors with rhabdomyoblastic differentiation. Although the condition may manifest sporadically, it typically affects adult patients with neurofibromatosis type 1. In this article, an extremely rare case of MTT with chest wall origin, which expanded into the left thoracic cavity, is reported. A 64-year-old male was admitted to the institution with sudden shortness of breath. Radiological examination revealed a large mass with massive pleural effusion occupying the patient\u2019s left hemithorax. A percutaneous needle biopsy was performed and the patient underwent subtotal tumor resection with left pleuropneumonectomy. Immunohistochemical study of postsurgical pathologic specimens confirmed the diagnosis of MTT. Despite extensive surgical removal, tumor recurrence was reported soon after resection, leading to patient\u2019s death 20\u00a0days after surgery due to acute respiratory failure. Investigation of rare MTT cases is necessary for understanding this condition.<\/jats:p>","DOI":"10.1093\/jscr\/rjz246","type":"journal-article","created":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T11:09:06Z","timestamp":1564571346000},"source":"Crossref","is-referenced-by-count":4,"title":["Malignant triton tumor of the left thoracic cavity: a case report"],"prefix":"10.1093","volume":"2019","author":[{"given":"Masashi","family":"Ishikawa","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoto","family":"Imamura","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumeta","family":"Shimazu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,8,29]]},"reference":[{"key":"2019091012531598000_ref1","first-page":"793","volume-title":"Recklinghausen's Neurofibromatosis, Sensory Neuromas and Motor Neuromas","author":"Masson","year":"1932"},{"key":"2019091012531598000_ref2","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/JTO.0b013e31819151ab","article-title":"Malignant triton tumor of the brachial plexus invading the left thoracic inlet. A rare differential diagnosis of Pancoast tumor","volume":"4","author":"Dartnell","year":"2009","journal-title":"J Thorac Oncol"},{"key":"2019091012531598000_ref3","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10014-013-0147-z","article-title":"Intracranial malignant triton tumor in a patient with neurofibromatosis type 1: case report and review of the literature","volume":"31","author":"Smith","year":"2014","journal-title":"Brain Tumor Pathol"},{"key":"2019091012531598000_ref4","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.4081\/rt.2009.e27","article-title":"Malignant triton tumor in the retroperitoneal space associated with neurofibromatosis type 1: a case study","volume":"1","author":"Hoshimoto","year":"2009","journal-title":"Rare Tumors"},{"key":"2019091012531598000_ref5","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1159\/000360576","article-title":"Malignant triton tumor of the sciatic nerve as a secondary malignancy after extended field radiotherapy and chemotherapy of Hodgkin's disease","volume":"7","author":"Nitsche","year":"2014","journal-title":"Case Rep Oncol"},{"key":"2019091012531598000_ref6","first-page":"277","article-title":"Malignant triton tumor of the chest wall invading the lung. A case report and literature review","volume":"17","author":"Kamperis","year":"2013","journal-title":"Hippokratia"},{"key":"2019091012531598000_ref7","doi-asserted-by":"crossref","first-page":"807","DOI":"10.3892\/ol.2014.1787","article-title":"Malignant triton tumor of the anterior mediastinum: a case report","volume":"7","author":"Ren","year":"2014","journal-title":"Oncol Lett"},{"key":"2019091012531598000_ref8","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1177\/1066896915583996","article-title":"Malignant peripheral nerve sheath tumor with rhabdomyosarcomatous and glandular elements: rare epithelial differentiation in a triton tumor","volume":"23","author":"Thway","year":"2015","journal-title":"Int J Surg Pathol"},{"key":"2019091012531598000_ref9","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1055\/s-2007-1012047","article-title":"A case of malignant triton tumor of the lung","volume":"44","author":"Suzuki","year":"1996","journal-title":"Thorac Cardiovasc Surg"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2019\/8\/rjz246\/29226563\/rjz246.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,24]],"date-time":"2022-09-24T22:50:06Z","timestamp":1664059806000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjz246\/5556290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,1]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjz246","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2019,8]]},"published":{"date-parts":[[2019,8,1]]},"article-number":"rjz246"}}