{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:50:30Z","timestamp":1782928230222,"version":"3.54.5"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T00:00:00Z","timestamp":1579651200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000761","name":"Imperial College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000761","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Mucinous appendiceal neoplasms are rare and diagnosis is often difficult as patients present with non-specific symptoms often suggestive of appendicitis only and most diagnoses are made following post-surgery histology examination. Here we present a case of a mucinous appendiceal adenocarcinoma with areas of both Low-grade Appendiceal Mucinous Neoplasm and High-grade Appendiceal Mucinous Neoplasm, in a ruptured appendix at a district general hospital. Without early detection and treatment these pathologies can lead to pseudomyxoma peritonei, a syndrome of progressive mucinous ascites. This case highlights the limitations of radiological studies, benefits of diagnostic laparoscopy and provides a rationale for removing the mesoappendix with the appendix during routine appendectomies.<\/jats:p>","DOI":"10.1093\/jscr\/rjz355","type":"journal-article","created":{"date-parts":[[2020,1,9]],"date-time":"2020-01-09T20:08:41Z","timestamp":1578600521000},"source":"Crossref","is-referenced-by-count":6,"title":["Mucinous appendiceal adenocarcinomas: a diagnostic challenge"],"prefix":"10.1093","volume":"2020","author":[{"given":"Ekta","family":"Sharma","sequence":"first","affiliation":[{"name":"Vascular Surgery Department, Imperial College Healthcare NHS Trust, St Mary\u2019s Hospital, London W2 1NY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyam Ajay","family":"Gokani","sequence":"additional","affiliation":[{"name":"Research Department of Primary Care & Population Health, University College London Royal Free Campus, London NW3 2QG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Neville","sequence":"additional","affiliation":[{"name":"Intensive Care Department, Imperial College Healthcare NHS Trust, Hammersmith Hospital, W12 0UQ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Sinha","sequence":"additional","affiliation":[{"name":"General Surgery Department, Ealing Hospital, London North West London Healthcare Trust, London UB1 3HW, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tushar","family":"Agarwal","sequence":"additional","affiliation":[{"name":"General Surgery Department, Ealing Hospital, London North West London Healthcare Trust, London UB1 3HW, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,1,22]]},"reference":[{"key":"2021011902173444700_ref1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1102\/1470-7330.2013.0003","article-title":"Mucinous neoplasms of the appendix: a current comprehensive clinicopathologic and imaging review","volume":"13","author":"Tirumani","year":"2013","journal-title":"Cancer Imaging"},{"key":"2021011902173444700_ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clcc.2018.11.007","article-title":"Review: pathology and its clinical relevance of mucinous appendiceal neoplasms and pseudomyxoma peritonei","volume":"18","author":"Legu\u00e9","year":"2019","journal-title":"Clin Colorectal Cancer"},{"key":"2021011902173444700_ref3","first-page":"503","article-title":"Surgical approach to appendiceal mucocele mimicking an adnexal complex mass: case report","volume":"28","author":"Scaffa","year":"2007","journal-title":"Eur J Gynaecol Oncol"},{"key":"2021011902173444700_ref4","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/01.sla.0000231705.40081.1a","article-title":"Survival analysis of pseudomyxoma peritonei patients treated by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy","volume":"245","author":"Smeenk","year":"2007","journal-title":"Ann Surg"},{"key":"2021011902173444700_ref5","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/ans.12495","article-title":"Appendiceal neuroendocrine neoplasms in the era of laparoscopic appendicectomy","volume":"84","author":"Davenport","year":"2014","journal-title":"ANZ J Surg"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2020\/1\/rjz355\/35922207\/rjz355.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2020\/1\/rjz355\/35922207\/rjz355.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T07:17:38Z","timestamp":1611040658000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjz355\/5688718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,1]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjz355","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,1]]},"published":{"date-parts":[[2020,1,1]]},"article-number":"rjz355"}}