{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:34:12Z","timestamp":1792427652585,"version":"4.5.0"},"reference-count":101,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sexual function after hysterectomy can be a concern for patients, and research remains inconclusive about changes in sexual function associated with hysterectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>We meta-analyzed studies on change in sexual function from pre- to posthysterectomy and the role of total vs subtotal hysterectomy and concomitant bilateral salpingo-oophorectomy (BSO) in differences in such change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We searched PubMed, Embase, and Cochrane databases from inception to January 2022. Two reviewers screened and included studies if they were published in a peer-reviewed journal and reported on sexual function pre- and posthysterectomy for benign nonprolapse indication. Methodological quality was assessed with the STROBE checklist. We used random effects multilevel models to meta-analyze standardized mean differences in pre- to postoperative sexual function and the posthysterectomy Female Sexual Function Index mean across study groups in R (RStudio).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcomes<\/jats:title>\n                    <jats:p>Outcomes included overall sexual function, dyspareunia, desire, arousal, lubrication, and orgasm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty-two articles were analyzed: 8 randomized controlled trials, 20 prospective studies, 2 retrospective studies, 1 cross-sectional study, and 1 secondary analysis, comprising a total of 4054 patients. Each study provided data for at least 1 outcome. Study quality was moderate, and effect sizes showed large between-study heterogeneity. Hysterectomy was not associated with significant change in overall sexual function irrespective of surgical route, with patients tending to report potentially remaining sexual dysfunction posthysterectomy. Cervix removal was not significantly associated with differences in magnitude of change. Hysterectomy without BSO was associated with significantly stronger improvement in lubrication and orgasm than hysterectomy with BSO, which was not the case for desire, arousal or overall sexual function. However, these significant differences were not replicated within studies that directly compared cases with and without BSO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Implications<\/jats:title>\n                    <jats:p>Clinicians should address remaining sexual dysfunction posthysterectomy, and BSO should not be considered if not medically required.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Strengths and Limitations<\/jats:title>\n                    <jats:p>We analyzed a comprehensive number of trials and studied clinically relevant factors that might relate to differences in change in sexual function. Conclusions need to be interpreted with caution since many studies showed moderate methodological quality and large effect size heterogeneity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Subtotal and total hysterectomy was not associated with significant change in overall sexual function irrespective of surgical route, with patients tending to report potentially remaining sexual dysfunction posthysterectomy. Hysterectomy without BSO was associated with significantly stronger improvement in lubrication and orgasm than hysterectomy with BSO. Future research on hysterectomy should analyze predictors of sexual function change trajectories, such as different indications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jsxmed\/qdac051","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T13:12:53Z","timestamp":1677676373000},"page":"447-466","source":"Crossref","is-referenced-by-count":44,"title":["Hysterectomy and sexual function: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"20","author":[{"given":"Suzanne J","family":"Dedden","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, M\u00e1xima Medical Centre , Veldhoven, 5504 DB , the Netherlands"},{"name":"GROW\u2013School of Oncology and Reproduction, Maastricht University , Maastricht, 6229 HZ , the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlene A","family":"Werner","sequence":"additional","affiliation":[{"name":"Department of Sexology and Psychosomatic Gynaecology, Amsterdam Reproduction and Development, Cancer Center Amsterdam, Amsterdam University Medical Center, University of Amsterdam , Amsterdam, 1105 AZ , the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorrit","family":"Steinweg","sequence":"additional","affiliation":[{"name":"Faculty of Health, Medicine and Life Sciences, Maastricht University , Maastricht, 6229 HX , the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit I","family":"Lissenberg-Witte","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Data Science, Amsterdam University Medical Center, Vrije Universiteit Amsterdam , Amsterdam, 1081 HV , the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith A F","family":"Huirne","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Amsterdam University Medical Center , Amsterdam, 1105 AZ , the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peggy M A J","family":"Geomini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, M\u00e1xima Medical Centre , Veldhoven, 5504 DB , the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques W M","family":"Maas","sequence":"additional","affiliation":[{"name":"GROW\u2013School of Oncology and Reproduction, Maastricht University , Maastricht, 6229 HZ , the Netherlands"},{"name":"Department of Obstetrics and Gynaecology, Maastricht University Medical Centre+ , Maastricht, 6229 HZ , the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,2,28]]},"reference":[{"key":"2023040105190703500_","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003677.pub5","volume-title":"Surgical Approach to Hysterectomy for Benign Gynaecological Disease","author":"Aarts","year":"2015"},{"issue":"5","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1055\/s-0043-107784","article-title":"Rates and routes of hysterectomy for benign indications in Austria 2002\u200a-\u200a2014","volume":"77","author":"Edler","year":"2017","journal-title":"Geburtshilfe Frauenheilkd"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ijgo.2010.11.011","article-title":"FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age","volume":"113","author":"Munro","year":"2011","journal-title":"Int J Gynaecol Obstet"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"34.e1","DOI":"10.1016\/j.ajog.2007.05.039","article-title":"Inpatient hysterectomy surveillance in the United States, 2000-2004","volume":"198","author":"Whiteman","year":"2008","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1600-0412.2011.01309.x","article-title":"Regional and temporal variation in hysterectomy rates and surgical routes for benign diseases in the Netherlands","volume":"91","author":"Hanstede","year":"2012","journal-title":"Acta Obstet Gynecol Scand"},{"key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ejogrb.2016.11.021","article-title":"Hysterectomies in Portugal (2000-2014): what has changed?","volume":"208","author":"Gante","year":"2017","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1258\/136218006779160607","article-title":"Hysterectomy and sexual function","volume":"12","author":"Mokate","year":"2006","journal-title":"British Menopause Society Journal"},{"issue":"7","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"575","DOI":"10.3109\/00016349409006276","article-title":"Predictive value of psychatric history, genital pain and menstrual symptoms for sexuality after hysterectomy","volume":"73","author":"Helstr\u00f6m","year":"1994","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"9","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1111\/j.1471-0528.1997.tb12053.x","article-title":"Bladder, bowel and sexual function after hysterectomy for benign conditions","volume":"104","author":"Thakar","year":"1997","journal-title":"Br J Obstet Gynaecol"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3109\/00016348309155778","article-title":"Supravaginal uterine amputation vs hysterectomy: effects on coital frequency and dyspareunia","volume":"62","author":"Kilkku","year":"1983","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"10","key":"2023040105190703500_","first-page":"781","article-title":"Cervical removal at hysterectomy for benign disease: risks and benefits","volume":"38","author":"Hasson","year":"1993","journal-title":"J Reprod Med"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ecl.2004.07.005","article-title":"Endocrine function of the postmenopausal ovary","volume":"33","author":"Rinaudo","year":"2004","journal-title":"Endocrinol Metab Clin N Am"},{"issue":"7","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.1210\/jc.2005-0212","article-title":"Androgen levels in adult females: changes with age, menopause, and oophorectomy","volume":"90","author":"Davison","year":"2005","journal-title":"J Clin Endocrin Metab"},{"issue":"suppl 1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1089\/152460900318795","article-title":"The aging ovary","volume":"9","author":"Shifren","year":"2000","journal-title":"J Womens Health Gend Based Med"},{"issue":"8","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"3040","DOI":"10.1210\/jc.2007-0581","article-title":"Ovarian androgen production in postmenopausal women","volume":"92","author":"Fogle","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1080\/13697137.2018.1535584","article-title":"Circulating androgen levels before and after oophorectomy in premenopausal and postmenopausal women","volume":"22","author":"Stanczyk","year":"2019","journal-title":"Climacteric"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3109\/13625189709165302","article-title":"Sex, hormones and the brain","volume":"2","author":"van Lunsen","year":"1997","journal-title":"Eur J Contracept Reprod Health Care"},{"issue":"6","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1097\/01.GME.0000143704.48324.46","article-title":"Genital vascular responsiveness and sexual feelings in midlife women: psychophysiologic, brain, and genital imaging studies","volume":"11","author":"van Lunsen","year":"2004","journal-title":"Menopause"},{"issue":"10","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/S2213-8587(19)30189-5","article-title":"Safety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data","volume":"7","author":"Islam","year":"2019","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"8","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S2213-8587(20)30239-4","article-title":"Associations between androgens and sexual function in premenopausal women: a crosssectional study","volume":"8","author":"Zheng","year":"2020","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"3","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.sxmr.2020.03.003","article-title":"Testosterone and vaginal function","volume":"8","author":"Maseroli","year":"2020","journal-title":"Sex Med Rev"},{"key":"2023040105190703500_","first-page":"25","volume-title":"Central Nervous System Anatomy and Neurochemistry of Sexual Desire","author":"Pfaus","year":"2018"},{"key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.yfrne.2017.12.006","article-title":"The neuroendocrinology of sexual attraction","volume":"51","author":"Le Mo\u00ebne","year":"2018","journal-title":"Front Neuroendocrinol"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"126","DOI":"10.3109\/01674829709085579","article-title":"Hormones and sexuality in postmenopausal women: a psychophysiological study","volume":"18","author":"Laan","year":"1997","journal-title":"J Psychosom Obstet Gynaecol"},{"issue":"3","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1677\/joe.1.06233","article-title":"The endocrinology of sexual arousal","volume":"186","author":"Bancroft","year":"2005","journal-title":"J Endocrinol"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ygyno.2010.12.326","article-title":"The impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual function in women who carry a BRCA mutation","volume":"121","author":"Finch","year":"2011","journal-title":"Gynecol Oncol"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/01.gme.0000172596.76272.06","article-title":"Hypoactive sexual desire disorder in postmenopausal women: US results from the Women\u2019s International Study of Health and Sexuality (WISHeS)","volume":"13","author":"Leiblum","year":"2006","journal-title":"Menopause"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"b2700","DOI":"10.1136\/bmj.b2700","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration","volume":"339","author":"Liberati","year":"2009","journal-title":"BMJ"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan\u2014a web and mobile app for systematic reviews","volume":"5","author":"Ouzzani","year":"2016","journal-title":"Syst Rev"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1080\/009262300278597","article-title":"The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function","volume":"26","author":"Rosen","year":"2000","journal-title":"J Sex Marital Ther"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF01542223","article-title":"The GRISS: a psychometric instrument for the assessment of sexual dysfunction","volume":"15","author":"Rust","year":"1986","journal-title":"Arch Sex Behav"},{"issue":"6, suppl","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1023\/A:1008925906947","article-title":"The McCoy Female Sexuality Questionnaire","volume":"9","author":"McCoy","year":"2000","journal-title":"Qual Life Res"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0022-3999(86)90069-3","article-title":"The Psychosocial Adjustment to Illness Scale (PAIS)","volume":"30","author":"Derogatis","year":"1986","journal-title":"J Psychosom Res"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1080\/00926239708403933","article-title":"The Derogatis Interview for Sexual Functioning (DISF\/DISF-SR): an introductory report","volume":"23","author":"Derogatis","year":"1997","journal-title":"J Sex Marital Ther"},{"key":"2023040105190703500_","volume-title":"Sexualitat Und Partnerschaft: Grundlagen Und Praxis Psychologischer Beratung (TSST)","author":"Zimmer","year":"1985"},{"key":"2023040105190703500_","first-page":"194","volume-title":"Measuring Functioning and Well-being","author":"Sherbourne","year":"1992"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1080\/009262300278623","article-title":"The Arizona Sexual Experience Scale (ASEX): reliability and validity","volume":"26","author":"McGahuey","year":"2000","journal-title":"J Sex Marital Ther"},{"issue":"5","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1080\/00926230290001510","article-title":"Evaluation of a short scale to assess female sexual functioning","volume":"28","author":"Dennerstein","year":"2002","journal-title":"J Sex Marital Ther"},{"issue":"12","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.ijsu.2014.07.014","article-title":"Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration","volume":"12","author":"Vandenbroucke","year":"2014","journal-title":"Int J Surg"},{"key":"2023040105190703500_","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2021"},{"key":"2023040105190703500_","volume-title":"RStudio: Integrated Development Environment for R","author":"RStudio Team","year":"2021"},{"issue":"3","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v036.i03","article-title":"Conducting meta-analyses in R with the metafor package","volume":"36","author":"Viechtbauer","year":"2010","journal-title":"J Stat Softw"},{"key":"2023040105190703500_","volume-title":"Dmetar: Companion R Package for the Guide \u201cDoing Meta-analysis in R.\u201d","author":"Harrer","year":"2019"},{"key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.ejogrb.2020.01.047","article-title":"Hysterectomy and sexual (dys)function: an analysis of sexual dysfunction after hysterectomy and a search for predictive factors","volume":"247","author":"Dedden","year":"2020","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"3","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3102\/10769986030003261","article-title":"Bias and efficiency of meta-analytic variance estimators in the random-effects model","volume":"30","author":"Viechtbauer","year":"2005","journal-title":"J Educ Behav Stat"},{"key":"2023040105190703500_","doi-asserted-by":"crossref","DOI":"10.1201\/9781003107347","volume-title":"Doing Meta-analysis With R: A Hands-on Guide","author":"Harrer","year":"2021"},{"issue":"7414","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"issue":"10","key":"2023040105190703500_","first-page":"594","article-title":"The outcome of subtotal abdominal hysterectomy","volume":"15","author":"Iftikhar","year":"2005","journal-title":"J Coll Physicians Surg Pak"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3109\/00016348309155779","article-title":"Supravaginal uterine amputation vs hysterectomy: effects on libido and orgasm","volume":"62","author":"Kilkku","year":"1983","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4274\/tjod.78803","article-title":"Comparison of libido, Female Sexual Function Index, and Arizona scores in women who underwent laparoscopic or conventional abdominal hysterectomy","volume":"14","author":"Kayata\u015f","year":"2017","journal-title":"Turk J Obstet Gynecol"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.jmig.2019.03.018","article-title":"Sexual function following laparoscopic versus transvaginal closure of the vaginal vault after laparoscopic hysterectomy: secondary analysis of a randomized trial by the Italian Society of Gynecological Endoscopy using a validated questionnaire","volume":"27","author":"Uccella","year":"2020","journal-title":"J Minim Invasive Gynecol"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"26","DOI":"10.2478\/chilat-2014-0105","article-title":"Quality of female sexual function after conventional abdominal hysterectomy\u2014three month observation","volume":"14","author":"Briedite","year":"2014","journal-title":"Acta Chirurgica Latviensis"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/13697130601170018","article-title":"A prospective study of outcomes after hysterectomy in mid-aged Australian-born women","volume":"10","author":"Guthrie","year":"2007","journal-title":"Climacteric"},{"issue":"5","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/j.1471-0528.2007.01306.x","article-title":"The effect of hysterectomy or levonorgestrel-releasing intrauterine system on sexual functioning among women with menorrhagia: a 5-year randomised controlled trial","volume":"114","author":"Halmesm\u00e4ki","year":"2007","journal-title":"BJOG"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00404-018-4812-7","article-title":"Sexual functioning after total versus subtotal laparoscopic hysterectomy","volume":"298","author":"Berlit","year":"2018","journal-title":"Arch Gynecol Obstet"},{"issue":"10","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1080\/08941939.2020.1744774","article-title":"Abdominal hysterectomy with a uterine manipulator minimizes vaginal shortening: a randomized controlled trial","volume":"34","author":"Kiyak","year":"2021","journal-title":"J Investig Surg"},{"issue":"5","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1080\/01443615.2021.1948512","article-title":"Vaginal length and sexual function after vertical versus horizontal closure of the vaginal cuff after abdominal hysterectomy: a randomised clinical trial","volume":"42","author":"Taha","year":"2022","journal-title":"J Obstet Gynaecol"},{"issue":"6","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.jmig.2016.07.007","article-title":"Comparison of 2 methods of vaginal cuff closure at laparoscopic hysterectomy and their effect on female sexual function and vaginal length: a randomized clinical study","volume":"23","author":"Bastu","year":"2016","journal-title":"J Minim Invasive Gynecol"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3109\/00016340903353276","article-title":"A randomized trial comparing changes in sexual health and psychological well-being after subtotal and total hysterectomies","volume":"89","author":"Ellstr\u00f6m Engh","year":"2010","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"3","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1743-6109.2006.00229.x","article-title":"The psychosocial outcomes of total and subtotal hysterectomy: a randomized controlled trial","volume":"3","author":"Flory","year":"2006","journal-title":"J Sex Med"},{"issue":"6","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1097\/01.AOG.0000160428.81371.be","article-title":"Sexual functioning after total compared with supracervical hysterectomy: a randomized trial","volume":"105","author":"Kuppermann","year":"2005","journal-title":"Obstet Gynecol"},{"issue":"9252","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0140-6736(00)03615-1","article-title":"Quality of life and cost-effectiveness of levonorgestrel-releasing intrauterine system versus hysterectomy for treatment of menorrhagia: a randomised trial","volume":"357","author":"Hurskainen","year":"2001","journal-title":"Lancet"},{"issue":"7026","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1136\/bmj.312.7026.280","article-title":"Randomised trial comparing hysterectomy with endometrial ablation for dysfunctional uterine bleeding: psychiatric and psychosocial aspects","volume":"312","author":"Alexander","year":"1996","journal-title":"BMJ"},{"issue":"16","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"3608","DOI":"10.3390\/jcm10163608","article-title":"Impact of hysterectomy on quality of life, urinary incontinence, sexual functions and urethral length","volume":"10","author":"Skorupska","year":"2021","journal-title":"J Clin Med"},{"key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/8247207","article-title":"Comparison of the effects of total laparoscopic hysterectomy and total abdominal hysterectomy on sexual function and quality of life","volume":"2020","author":"Beyan","year":"2020","journal-title":"Biomed Res Int"},{"issue":"5","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"693","DOI":"10.31083\/j.ceog.2020.05.5389","article-title":"Evaluation of sexual functions and quality of life in female patients after hysterectomy for benign symptomatic diseases","volume":"47","author":"Ko\u015far Can","year":"2020","journal-title":"Clin Exp Obstet Gynecol"},{"issue":"2","key":"2023040105190703500_","first-page":"442\u2013450","article-title":"Alteration of sexual function among females after laparoscopic and abdominal hysterectomy","volume":"2","author":"El-Bassioune","year":"2020","journal-title":"IJMA"},{"issue":"suppl 1","key":"2023040105190703500_","first-page":"216","article-title":"The effect of laparoscopic hysterectomy on sexual function and quality of life: 12-month follow-up results","volume":"43","author":"Sukgen","year":"2018","journal-title":"Cuk Med J"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4274\/tjod.71245","article-title":"The impact of abdominal and laparoscopic hysterectomies on women\u2019s sexuality and psychological condition","volume":"13","author":"K\u00fcrek Eken","year":"2016","journal-title":"Turk J Obstet Gynecol"},{"issue":"3","key":"2023040105190703500_","first-page":"700","article-title":"The effect of total hysterectomy on sexual function and depression","volume":"31","author":"Goktas","year":"2015","journal-title":"Pak J Med Sci"},{"issue":"6","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"S106","DOI":"10.1016\/j.jmig.2015.08.287","article-title":"Vaginal length and sexual function following total laparoscopic hysterectomy","volume":"22","author":"Shiber","year":"2015","journal-title":"J Minim Invasive Gynecol"},{"issue":"9","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1111\/jsm.12623","article-title":"Influences of different hysterectomy techniques on patients\u2019 postoperative sexual function and quality of life","volume":"11","author":"Radosa","year":"2014","journal-title":"J Sex Med"},{"issue":"12","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1111\/j.1600-0412.2011.01255.x","article-title":"Does conventional or single port laparoscopically assisted vaginal hysterectomy affect female sexual function?","volume":"90","author":"Lee","year":"2011","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3109\/13697137.2010.532251","article-title":"The effect of hysterectomy and\/or oophorectomy on sexual satisfaction","volume":"14","author":"S\u00f6zeri-Varma","year":"2011","journal-title":"Climacteric"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.maturitas.2008.09.015","article-title":"The effect of hysterectomy and bilaterally salpingo-oophorectomy on sexual function in post-menopausal women","volume":"61","author":"Celik","year":"2008","journal-title":"Maturitas"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1176\/appi.psy.49.2.137","article-title":"Risk factors for major depressive disorder and the psychological impact of hysterectomy: a prospective investigation","volume":"49","author":"Yen","year":"2008","journal-title":"Psychosomatics"},{"issue":"3","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s11195-008-9085-9","article-title":"Hysterectomy\u2019s psychosexual effects in Turkish women","volume":"26","author":"Bayram","year":"2008","journal-title":"Sex Disabil"},{"issue":"suppl 4","key":"2023040105190703500_","first-page":"S112","article-title":"Sexuality after total abdominal hysterectomy in Srinagarind hospital","volume":"89","author":"Punushapai","year":"2006","journal-title":"J Med Assoc Thail"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3109\/01674820209093415","article-title":"Women\u2019s sexual behavior, body image and satisfaction with surgical outcomes after hysterectomy: a comparison of vaginal and abdominal surgery","volume":"23","author":"G\u00fctl","year":"2002","journal-title":"J Psychosom Obstet Gynaecol"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.fertnstert.2004.12.008","article-title":"Perimenopausal androgen decline after oophorectomy does not influence sexuality or psychological well-being","volume":"83","author":"Aziz","year":"2005","journal-title":"Fertil Steril"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1097\/00006250-199404000-00012","article-title":"The Maine Women\u2019s Health Study: I. Outcomes of hysterectomy","volume":"83","author":"Carlson","year":"1994","journal-title":"Obstet Gynecol"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jogoh.2018.11.004","article-title":"Comparison of female sexual function in women who underwent abdominal or vaginal hysterectomy with or without bilateral salpingo-oophorectomy","volume":"48","author":"Do\u011fanay","year":"2019","journal-title":"J Gynecol Obstet Hum Reprod"},{"issue":"3","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000184679","article-title":"Patient satisfaction after laparoscopic total or supracervical hysterectomy","volume":"67","author":"Kafy","year":"2009","journal-title":"Gynecol Obstet Investig"},{"issue":"7","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"365","DOI":"10.5603\/GP.2019.0060","article-title":"Laparoscopic versus vaginal cuff closure in laparoscopic hysterectomy: does it affect female sexuality?","volume":"90","author":"Dundar","year":"2019","journal-title":"Ginekol Pol"},{"issue":"2, pt 1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1097\/01.AOG.0000252700.03133.8b","article-title":"Oophorectomy in premenopausal women: health-related quality of life and sexual functioning","volume":"109","author":"Teplin","year":"2007","journal-title":"Obstet Gynecol"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1081\/COPD-200053374","article-title":"Assessing the minimally clinically significant difference: scientific considerations, challenges and solutions","volume":"2","author":"Sloan","year":"2005","journal-title":"COPD: J Chron Obstruct Pulmon Dis"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/00926230590475206","article-title":"The Female Sexual Function Index (FSFI): cross-validation and development of clinical cutoff scores","volume":"31","author":"Wiegel","year":"2005","journal-title":"J Sex Marital Ther"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.jmig.2021.10.012","article-title":"Effect of hysterectomy due to benign diseases on female sexual function: a systematic review and meta-analysis","volume":"29","author":"Kazemi","year":"2022","journal-title":"J Minim Invasive Gynecol"},{"issue":"7432","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1136\/bmj.37984.623889.F6","article-title":"The eVALuate study: two parallel randomised trials, one comparing laparoscopic with abdominal hysterectomy, the other comparing laparoscopic with vaginal hysterectomy","volume":"328","author":"Garry","year":"2004","journal-title":"BMJ"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ejogrb.2010.03.031","article-title":"Vaginal length and incidence of dyspareunia after total abdominal versus vaginal hysterectomy","volume":"151","author":"Abdelmonem","year":"2010","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.ejogrb.2012.12.005","article-title":"Comparison of prevalence of hypoactive sexual desire disorder (HSDD) in women after five different hysterectomy procedures","volume":"167","author":"Lermann","year":"2013","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"4","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.jmig.2007.02.015","article-title":"Pelvic organ function in randomized patients undergoing laparoscopic or abdominal hysterectomy","volume":"14","author":"Kluivers","year":"2007","journal-title":"J Minim Invasive Gynecol"},{"issue":"2","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/14681990500113195","article-title":"The involvement of the human cervix in reproduction and sex","volume":"20","author":"Levin","year":"2005","journal-title":"Sex Relatsh Ther"},{"issue":"3","key":"2023040105190703500_","first-page":"453","article-title":"A randomized comparison of total or supracervical hysterectomy: surgical complications and clinical outcomes","volume":"102","author":"Learman","year":"2003","journal-title":"Obstet Gynecol"},{"issue":"17","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1056\/NEJMoa013336","article-title":"Outcomes after total versus subtotal abdominal hysterectomy","volume":"347","author":"Thakar","year":"2002","journal-title":"N Engl J Med"},{"issue":"12","key":"2023040105190703500_","first-page":"1088","article-title":"Randomised controlled trial of total compared with subtotal hysterectomy with one-year follow up results","volume":"110","author":"Gimbel","year":"2003","journal-title":"BJOG"},{"issue":"8","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1001\/jamaoncol.2021.1590","article-title":"Association of salpingectomy with delayed oophorectomy versus salpingo-oophorectomy with quality of life in BRCA1\/2 pathogenic variant carriers: a nonrandomized controlled trial","volume":"7","author":"Steenbeek","year":"2021","journal-title":"JAMA Oncol"},{"key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ejogrb.2021.08.001","article-title":"The impact of risk reducing bilateral salpingo-oophorectomy on sexual function in BRCA1\/2 mutation carriers and women with lynch syndrome: a systematic review and meta-analysis","volume":"265","author":"Kershaw","year":"2021","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3758\/s13423-017-1343-3","article-title":"Bayesian inference for psychology. Part I: theoretical advantages and practical ramifications","volume":"25","author":"Wagenmakers","year":"2018","journal-title":"Psychon Bull Rev"},{"issue":"1","key":"2023040105190703500_","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12874-020-00980-6","article-title":"Bayesian alternatives to null hypothesis significance testing in biomedical research: a non-technical introduction to Bayesian inference with JASP","volume":"20","author":"Kelter","year":"2020","journal-title":"BMC Med Res Methodol"},{"key":"2023040105190703500_","volume-title":"Metafor Package: Bias and Sensitivity Diagnostics","author":"Viechtbauer","year":"2015"}],"container-title":["The Journal of Sexual Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/20\/4\/447\/49714746\/qdac051.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/20\/4\/447\/49714746\/qdac051.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T21:36:48Z","timestamp":1701985008000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jsm\/article\/20\/4\/447\/7059565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,28]]},"references-count":101,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,2,28]]},"published-print":{"date-parts":[[2023,3,31]]}},"URL":"https:\/\/doi.org\/10.1093\/jsxmed\/qdac051","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.742555360.793598015","asserted-by":"object"}]},"ISSN":["1743-6095","1743-6109"],"issn-type":[{"value":"1743-6095","type":"print"},{"value":"1743-6109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,4]]},"published":{"date-parts":[[2023,2,28]]}}}