{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:58:30Z","timestamp":1790873910781,"version":"4.1.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T00:00:00Z","timestamp":1726790400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"2024 International and Hong Kong, Macao, and Taiwan Cooperation Office Construction Plan Foundation of the Third Affiliated Hospital of Sun Yat-sen University"},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["202307820010"],"award-info":[{"award-number":["202307820010"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Although the normal intravaginal ejaculation latency time (NIELT) as subjectively perceived by patients with premature ejaculation (PE) and expected IELT (EIELT), which represents the individual\u2019s expectations of what treatment for PE would achieve, are critically influential in the treatment of patients with PE, there is a significant dearth of exploratory research on NIELT and EIELT among patients with PE.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>To explore the NIELT and EIELT of patients with PE, understand why patients with PE perceive such a long IELT as normal, and identify factors associated with EIELT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We recruited both patients with PE and control subjects, and analyzed the parameters related to IELT using detailed interviews and questionnaires.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Outcomes<\/jats:title>\n                  <jats:p>Parameters related to IELT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 592 individuals (mean age 29.6\u2009\u00b1\u20096.2) were included in the study, comprising 466 patients with PE (mean age 28.3\u2009\u00b1\u20095.4) and 126 non-PE individuals (mean age 34.6\u2009\u00b1\u20096.5). The actual perceived intravaginal ejaculation latency time (PIELT), referring to the patient\u2019s self-assessed IELT at baseline, as well as NIELT, and EIELT of patients with PE, were 1.0 (1.0 \u2212 2.0), 14.0 (10.0 \u2212 15.0), and 15.0 (10.0 \u2212 20.0), respectively. The control group\u2019s PIELT and EIELT were 15.0 (10.0 \u2212 20.0) and 20.0 (15.0 \u2212 24.3), respectively, showing statistical differences compared with the PIELT and EIELT in the PE group. In the PE group and the control group, 31.5% and 57.9% of individuals, respectively, have an EIELT greater than the average actual normal ejaculatory latency time of 15.0\u00a0minutes. Among patients with PE, 51.3% expressed a NIELT &amp;gt;10\u00a0minutes, identical to the EIELT in a higher percentage (59.4%). The control group\u2019s EIELT is 5\u00a0minutes longer than the PE group\u2019s EIELT. Multivariable linear regression analysis showed that age, marital status, education level, BMI, satisfaction evaluation of PIELT, PEDT score, and IIEF-6 score were not associated with EIELT; only NIELT (beta\u2009=\u20090.817, P\u2009&amp;lt;\u20090.001) and PIELT (beta\u2009=\u20090.056, P\u2009=\u20090.044) were related to EIELT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Clinical implications<\/jats:title>\n                  <jats:p>Sexual health care providers should be aware that patients with PE have excessively high expectations for IELT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Strengths and limitation<\/jats:title>\n                  <jats:p>The first study explores why patients with clinically diagnosed PE perceive long IELT as normal and examines factors associated with EIELT. Further validation is needed in different cultural contexts.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Patients with PE often have excessively high expectations regarding IELT, primarily due to their insufficient understanding of IELT.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jsxmed\/qdae127","type":"journal-article","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T04:12:15Z","timestamp":1725509535000},"page":"1137-1143","source":"Crossref","is-referenced-by-count":7,"title":["Perception of normal and treatment level ejaculatory latency times in men with premature ejaculation"],"prefix":"10.1093","volume":"21","author":[{"given":"Chunlin","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Infertility and Sexual Medicine, The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou 510630 ,","place":["China"]},{"name":"Department of Systems Medicine, University of Rome Tor Vergata , Rome 00133 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0081-7163","authenticated-orcid":false,"given":"Elena","family":"Colonnello","sequence":"additional","affiliation":[{"name":"Department of Systems Medicine, University of Rome Tor Vergata , Rome 00133 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1210-2843","authenticated-orcid":false,"given":"Andrea","family":"Sansone","sequence":"additional","affiliation":[{"name":"Department of Systems Medicine, University of Rome Tor Vergata , Rome 00133 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Systems Medicine, University of Rome Tor Vergata , Rome 00133 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dake","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Systems Medicine, University of Rome Tor Vergata , Rome 00133 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuele A","family":"Jannini","sequence":"additional","affiliation":[{"name":"Department of Systems Medicine, University of Rome Tor Vergata , Rome 00133 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Infertility and Sexual Medicine, The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou 510630 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,9,20]]},"reference":[{"issue":"4","key":"2024121305521288700_ref1","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1111\/j.1743-6109.2005.00070.x","article-title":"A multinational population survey of intravaginal ejaculation latency time","volume":"2","author":"Waldinger","year":"2005","journal-title":"J Sex Med"},{"issue":"6","key":"2024121305521288700_ref2","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1111\/jsm.12504","article-title":"An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE)","volume":"11","author":"Althof","year":"2014","journal-title":"J Sex Med"},{"issue":"5","key":"2024121305521288700_ref3","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1016\/j.fertnstert.2015.08.035","article-title":"Premature ejaculation: old story, new insights","volume":"104","author":"Jannini","year":"2015","journal-title":"Fertil Steril"},{"issue":"2","key":"2024121305521288700_ref4","doi-asserted-by":"publisher","first-page":"338","DOI":"10.5534\/wjmh.230030","article-title":"Efficacy of various treatment in premature ejaculation: systematic review and network meta-analysis","volume":"42","author":"Lee","year":"2024","journal-title":"World J Men's Health"},{"issue":"2","key":"2024121305521288700_ref5","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1002\/sm2.27","article-title":"An evidence-based unified definition of lifelong and acquired premature ejaculation: report of the second international society for sexual medicine ad hoc committee for the definition of premature ejaculation","volume":"2","author":"Serefoglu","year":"2014","journal-title":"Sexual Med"},{"issue":"3","key":"2024121305521288700_ref6","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1097\/JU.0000000000002392","article-title":"Disorders of ejaculation: an AUA\/SMSNA guideline","volume":"207","author":"Shindel","year":"2022","journal-title":"J Urol"},{"issue":"5","key":"2024121305521288700_ref7","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1007\/s40618-020-01458-4","article-title":"Management of premature ejaculation: a clinical guideline from the Italian Society of Andrology and Sexual Medicine (SIAMS)","volume":"44","author":"Sansone","year":"2021","journal-title":"J Endocrinol Investig"},{"issue":"1","key":"2024121305521288700_ref8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40001-015-0169-6","article-title":"Perceptions of normal and abnormal ejaculatory latency times: an observational study in Ghanaian males and females","volume":"20","author":"Amidu","year":"2015","journal-title":"Eur J Med Res"},{"issue":"7","key":"2024121305521288700_ref9","doi-asserted-by":"publisher","first-page":"1598","DOI":"10.1111\/and.14425","article-title":"Reasons and treatment strategy for discontinuation of dapoxetine treatment in premature ejaculation patients in China: a retrospective observational study","volume":"54","author":"Zhong","year":"2022","journal-title":"Andrologia"},{"issue":"5","key":"2024121305521288700_ref10","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/j.jsxm.2021.01.187","article-title":"Self-reported shorter than desired ejaculation latency and related distress\u2014prevalence and clinical correlates: results from the European male ageing study","volume":"18","author":"Corona","year":"2021","journal-title":"J Sex Med"},{"issue":"2","key":"2024121305521288700_ref11","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/j.eururo.2007.01.028","article-title":"Development and validation of a premature ejaculation diagnostic tool","volume":"52","author":"Symonds","year":"2007","journal-title":"Eur Urol"},{"issue":"5","key":"2024121305521288700_ref12","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1016\/j.jsxm.2019.02.014","article-title":"Erectile dysfunction and premature ejaculation in homosexual and heterosexual men: a systematic review and meta-analysis of comparative studies","volume":"16","author":"Barbonetti","year":"2019","journal-title":"J Sex Med"},{"issue":"2","key":"2024121305521288700_ref13","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/S0090-4295(99)00099-0","article-title":"Diagnostic evaluation of the erectile function domain of the international index of erectile function","volume":"54","author":"Cappelleri","year":"1999","journal-title":"Urology"},{"issue":"3","key":"2024121305521288700_ref14","doi-asserted-by":"publisher","first-page":"321","DOI":"10.4103\/aja202364","article-title":"Validity of self-reported male sexual function scales in a young Chinese population: a comparative study with clinician-assisted evaluation","volume":"26","author":"Zhang","year":"2024","journal-title":"Asian J Androl"},{"issue":"6","key":"2024121305521288700_ref15","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1111\/j.1743-6109.2008.00825.x","article-title":"Impact of premature ejaculation: the psychological, quality of life, and sexual relationship consequences","volume":"5","author":"Rosen","year":"2008","journal-title":"J Sex Med"},{"issue":"1","key":"2024121305521288700_ref16","doi-asserted-by":"publisher","first-page":"e37","DOI":"10.1016\/j.esxm.2016.11.002","article-title":"Prevalence and associated factors of premature ejaculation in the Anhui male population in China: evidence-based unified definition of lifelong and acquired premature ejaculation","volume":"5","author":"Gao","year":"2017","journal-title":"Sexual Med"},{"issue":"8","key":"2024121305521288700_ref17","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1056\/NEJMoa067423","article-title":"A study of sexuality and health among older adults in the United States","volume":"357","author":"Lindau","year":"2007","journal-title":"N Engl J Med"},{"issue":"4","key":"2024121305521288700_ref18","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1080\/00224499.2019.1663480","article-title":"Exploring the role of sexual avoidance in male sexual dysfunction","volume":"57","author":"Stephenson","year":"2020","journal-title":"J Sex Res"},{"issue":"9","key":"2024121305521288700_ref19","doi-asserted-by":"publisher","first-page":"2243","DOI":"10.1111\/jsm.12551","article-title":"Female partner's perception of premature ejaculation and its impact on relationship breakups, relationship quality, and sexual satisfaction","volume":"11","author":"Burri","year":"2014","journal-title":"J Sex Med"},{"issue":"3","key":"2024121305521288700_ref20","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1080\/2090598X.2021.1948159","article-title":"Premature ejaculation: an investigative study into assumptions, facts and perceptions of patients from the Middle East (PEAP STUDY)","volume":"19","author":"Albakr","year":"2021","journal-title":"Arab J Urol"},{"issue":"1","key":"2024121305521288700_ref21","doi-asserted-by":"crossref","DOI":"10.2196\/jmir.1035","article-title":"Using the internet for health-related activities: findings from a national probability sample","volume":"11","author":"Atkinson","year":"2009","journal-title":"J Med Internet Res"},{"issue":"2","key":"2024121305521288700_ref22","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.jadohealth.2010.01.002","article-title":"Quality and accuracy of sexual health information web sites visited by young people","volume":"47","author":"Buhi","year":"2010","journal-title":"J Adolesc Health"},{"issue":"7","key":"2024121305521288700_ref23","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1111\/j.1464-410X.2008.07845.x","article-title":"Perceived control over ejaculation is central to treatment benefit in men with premature ejaculation: results from phase III trials with dapoxetine","volume":"102","author":"Shabsigh","year":"2008","journal-title":"BJU Int"},{"issue":"2","key":"2024121305521288700_ref24","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1111\/andr.13403","article-title":"From waterloo to the Great Wall: a retrospective, multicenter study on the clinical practice and cultural attitudes in the management of premature ejaculation","volume":"12","author":"Sansone","year":"2024","journal-title":"China Androl"},{"issue":"5","key":"2024121305521288700_ref25","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1111\/andr.12220","article-title":"The impact of premature ejaculation on the subjective perception of orgasmic intensity: validation and standardisation of the \u2018Orgasmometer\u2019","volume":"4","author":"Limoncin","year":"2016","journal-title":"Andrology"},{"key":"2024121305521288700_ref26","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/978-3-030-36222-5_6","volume-title":"Cultural Differences and the Practice of Sexual Medicine: A Guide for Sexual Health Practitioners","author":"Colonnello","year":"2020"},{"key":"2024121305521288700_ref27","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.pbb.2014.01.004","article-title":"The 5-HT1A receptor C (1019) G polymorphism influences the intravaginal ejaculation latency time in Dutch Caucasian men with lifelong premature ejaculation","volume":"121","author":"Janssen","year":"2014","journal-title":"Pharmacol Biochem Behav"},{"issue":"6","key":"2024121305521288700_ref28","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1111\/j.1743-6109.2005.00142.x","article-title":"Thyroid-stimulating hormone assessments in a Dutch cohort of 620 men with lifelong premature ejaculation without erectile dysfunction","volume":"2","author":"Waldinger","year":"2005","journal-title":"J Sex Med"},{"issue":"2","key":"2024121305521288700_ref29","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/s41585-020-00417-1","article-title":"Redefining a sexual medicine paradigm: subclinical premature ejaculation as a new taxonomic entity","volume":"18","author":"Colonnello","year":"2021","journal-title":"Nat Rev Urol"}],"container-title":["The Journal of Sexual Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/21\/12\/1137\/60927241\/qdae127.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/21\/12\/1137\/60927241\/qdae127.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T05:52:21Z","timestamp":1734069141000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jsm\/article\/21\/12\/1137\/7762458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,20]]},"references-count":29,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,9,20]]},"published-print":{"date-parts":[[2024,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jsxmed\/qdae127","relation":{},"ISSN":["1743-6095","1743-6109"],"issn-type":[{"value":"1743-6095","type":"print"},{"value":"1743-6109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,12]]},"published":{"date-parts":[[2024,9,20]]}}}