{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:10:20Z","timestamp":1781737820309,"version":"3.54.5"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,12,8]],"date-time":"2024-12-08T00:00:00Z","timestamp":1733616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Pelvic arterial (PLA) stenosis is associated with arterial insufficiency of the penis and erectile dysfunction (ED), but the effect of different severities of PLA stenosis on ED remains unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>To investigate how different severities of PLA stenosis affect erectile function.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We included patients who visited our clinic for ED and underwent computed tomography angiography (CTA) and dynamic duplex sonography (DUS). The erectile hardness score (EHS), simplified International Index of Erectile Function (IIEF-5), DUS and CTA results, and flow index (FI) calculated from the peak systolic velocity (PSV) and PLA stenosis percentages were analyzed. EHS\u2009&amp;lt;\u20093 was defined as significant ED. PLA stenosis was analyzed by the mean PLA (average of the right and left PLA) and unilateral or bilateral stenoses. According to severity, stenosis was classified as mild, moderate, or severe.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Outcomes<\/jats:title>\n                  <jats:p>Subjective and objective parameters, including the IIEF-5 score, EHS, PSV, and FI, in relation to different severities of PLA stenosis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The study included 182 patients. Vascular parameters such as the mean PSV, PLA stenosis, and FI correlated with EHS and IIEF-5 scores. Receiver operating characteristic analyses for predicting EHS\u2009\u2265\u20093 showed that all vascular parameters had acceptable discriminatory ability. During the analysis performed using the mean PSA stenosis, EHS decreased in patients with mild and severe mean PLA stenosis, although a PSV drop was noted only in severe cases. The proportion achieving EHS 3 significantly dropped in patients with at least mild mean PLA stenosis. Using unilateral or bilateral PLA stenosis, the EHS significantly dropped in patients with severe unilateral and bilateral PLA stenosis, with PSV decreasing on the affected side in severe unilateral stenosis. However, the mean PSV did not drop despite different unilateral stenosis severities. The proportion achieving EHS 3 significantly dropped among patients with at least moderate unilateral PLA stenosis and bilateral PLA stenosis but not in mild unilateral cases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Clinical Implications<\/jats:title>\n                  <jats:p>The severity of PLA stenosis is correlated with the risk of ED.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Strengths &amp; Limitations<\/jats:title>\n                  <jats:p>The strength of this study lies in its analysis of the effect of PLA stenosis on erectile function from various perspectives, including unilateral, bilateral, and mean stenosis. However, the absence of validation regarding the outcomes of endovascular therapy is a limitation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Mild mean PLA stenosis and moderate unilateral PLA stenosis are associated with increased risks of ED; however, mild unilateral PLA stenosis does not affect erectile function.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jsxmed\/qdae172","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T23:24:33Z","timestamp":1733873073000},"page":"282-290","source":"Crossref","is-referenced-by-count":3,"title":["Effect of pelvic arterial stenosis on erectile function: determining the severity threshold for erectile dysfunction"],"prefix":"10.1093","volume":"22","author":[{"given":"Wei-Lun","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Urology , National Taiwan University Hospital and College of Medicine, Zhongzheng Dist., Taipei City 100225,","place":["Taiwan (R.O.C.)"]},{"name":"Division of Urology , Department of Surgery, E-Da Hospital, Yanchao Dist. Township, Kaohsiung City 824005,","place":["Taiwan (R.O.C.)"]},{"name":"Department of Nursing , I-Shou University, Dashu District, Kaohsiung City 84001,","place":["Taiwan (R.O.C.)"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Yung","family":"Tung","sequence":"additional","affiliation":[{"name":"Department of Urology , National Taiwan University Hospital and College of Medicine, Zhongzheng Dist., Taipei City 100225,","place":["Taiwan (R.O.C.)"]},{"name":"Department of Urology , Tainan Municipal An-Nan Hospital - China Medical University, Annan Dist., Tainan City 709,","place":["Taiwan (R.O.C.)"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Shin","family":"Tseng","sequence":"additional","affiliation":[{"name":"Department of Urology , National Taiwan University Hospital and College of Medicine, Zhongzheng Dist., Taipei City 100225,","place":["Taiwan (R.O.C.)"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzung-Dau","family":"Wang","sequence":"additional","affiliation":[{"name":"Cardiovascular Center and Division of Cardiology , Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, Zhongzheng Dist., Taipei City 100225, Taiwan (R.O.C.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Jeng","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging , National Taiwan University Hospital and College of Medicine, Zhongzheng Dist., Taipei City 100225, Taiwan (R.O.C.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyh-Horng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology , National Taiwan University Hospital and College of Medicine, Zhongzheng Dist., Taipei City 100225,","place":["Taiwan 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