{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:27:02Z","timestamp":1787318822910,"version":"build-2736575974"},"reference-count":64,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:00:00Z","timestamp":1736380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Interoception may be linked to central sensitization in chronic pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>We aimed to provide evidence about the role of interoceptive sensibility on central sensitization in vulvodynia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this cross-sectional study, a sample of females who received a diagnosis of vulvodynia filled out validated questionnaires relative to the individual level of interoceptive sensibility and the symptoms of central sensitization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcomes<\/jats:title>\n                    <jats:p>Interoceptive sensibility and symptoms of central sensitization were measured with the Multidimensional Assessment of Interoceptive Awareness and the Central Sensitization Inventory, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A lower level of trust and a higher level of emotional awareness predicted a higher number of central sensitization symptoms in our sample.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Implications<\/jats:title>\n                    <jats:p>Our evidence may increase the researchers\u2019 and physicians\u2019 attention toward the involvement of the central nervous system in pain phenomenology in vulvodynia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Strengths and Limitations<\/jats:title>\n                    <jats:p>No ad-hoc control sample was collected. No behavioral assessments about interoception were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>As registered in other chronic pain conditions, interoceptive sensibility may play a crucial role in the expressions of symptoms of central sensitization in vulvodynia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jsxmed\/qdae203","type":"journal-article","created":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T23:27:51Z","timestamp":1735255671000},"page":"491-499","source":"Crossref","is-referenced-by-count":10,"title":["The role of interoceptive sensibility on central sensitization to pain in vulvodynia"],"prefix":"10.1093","volume":"22","author":[{"given":"Federica","family":"Scarpina","sequence":"first","affiliation":[{"name":"\u201cRita Levi Montalcini\u201d Department of Neurosciences, University of Turin , 10126 Turin ,","place":["Italy"]},{"name":"Istituto di Ricovero e Cura a Carattere Scientifico Istituto Auxologico Italiano, Unit\u00e0 Operativa di Neurologia e Neuroriabilitazione , Ospedale San Giuseppe, 28824 Piancavallo (VCO) ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Elena","family":"Navarra","sequence":"additional","affiliation":[{"name":"\u201cRita Levi Montalcini\u201d Department of Neurosciences, University of Turin , 10126 Turin ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Varallo","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 \u00a0 Modena ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Bernorio","sequence":"additional","affiliation":[{"name":"Italian Association for Applied Sexology and Psychology , 20124 Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,1,9]]},"reference":[{"issue":"4","key":"2025041108411684400_ref1","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/S0959-4388(03)00090-4","article-title":"Interoception: the sense of the physiological condition of the body","volume":"13","author":"Craig","year":"2003","journal-title":"Curr Opin Neurobiol"},{"issue":"4","key":"2025041108411684400_ref2","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1111\/j.1756-8765.2012.01189.x","article-title":"The body in the mind: on the relationship between interoception and embodiment","volume":"4","author":"Herbert","year":"2012","journal-title":"Top Cogn Sci"},{"key":"2025041108411684400_ref3","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.biopsycho.2014.11.004","article-title":"Knowing your own heart: distinguishing interoceptive accuracy from interoceptive awareness","volume":"104","author":"Garfinkel","year":"2015","journal-title":"Biol Psychol"},{"key":"2025041108411684400_ref4","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.copsyc.2017.04.020","article-title":"Interoception and emotion","volume":"17","author":"Critchley","year":"2017","journal-title":"Curr Opin Psychol"},{"issue":"6","key":"2025041108411684400_ref5","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.bpsc.2017.12.004","article-title":"Interoception and mental health: a roadmap","volume":"3","author":"Khalsa","year":"2018","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"issue":"1708","key":"2025041108411684400_ref6","doi-asserted-by":"publisher","first-page":"20160018","DOI":"10.1098\/rstb.2016.0018","article-title":"Neural correlates of heart-focused interoception: a functional magnetic resonance imaging meta-analysis","volume":"371","author":"Schulz","year":"2016","journal-title":"Philos Trans R Soc B Biol Sci"},{"issue":"5","key":"2025041108411684400_ref7","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1097\/HRP.0000000000000170","article-title":"Interoception in psychiatric disorders: a review of randomized, controlled trials with interoception-based interventions","volume":"26","author":"Khoury","year":"2018","journal-title":"Harv Rev Psychiatry"},{"key":"2025041108411684400_ref8","doi-asserted-by":"publisher","first-page":"100584","DOI":"10.1016\/j.jocrd.2020.100584","article-title":"Dimensions of interoception in obsessive-compulsive disorder","volume":"27","author":"Eng","year":"2020","journal-title":"J Obsessive Compuls Relat Disord"},{"key":"2025041108411684400_ref9","doi-asserted-by":"publisher","first-page":"105142","DOI":"10.1016\/j.neubiorev.2023.105142","article-title":"What is the role of interoception in the symptom experience of people with a chronic condition? 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