{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T21:49:41Z","timestamp":1787953781816,"version":"build-2784847793"},"reference-count":84,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in women of fertile age. It is associated with somatic and psychological comorbidities and lower sexual function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To study which psychosocial factors predict sexual dysfunction, and dyadic and solitary sexual desire in women with PCOS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is an observational case control study amongst healthy heterosexual women with (n\u00a0=\u200968) and without PCOS (n\u00a0=\u200967), aged 18-40\u00a0years, in a steady relationship. All participants filled out questionnaires on sexuality (sexual function, sexual distress, sexual desire), psychosocial factors (general self-esteem, relationship satisfaction, body image, body self-consciousness, sexual esteem, sexual abuse), and mental health (anxiety and depression). Standard multiple regression analyses were performed to assess which factors predict sexual dysfunction and dyadic and solitary sexual desire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcomes<\/jats:title>\n                    <jats:p>sexual dysfunction, dyadic sexual desire, solitary sexual desire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Women with PCOS reported significantly more often sexual dysfunction (41.2% vs. 11.9%, P\u00a0&amp;lt;\u2009.001, \u03c6: 0.331) and lower dyadic sexual desire (P: .005, \u03b7: 0.057), but no difference in solitary sexual desire (P: .160, \u03b7: 0.015) compared to women without PCOS. Also, women with PCOS reported significantly less positive body image (P: .012, \u03b7: 0.047), higher body self-consciousness (P: .011, \u03b7: 0.048), higher anxiety (P: .002, \u03b7: 0.072), higher depression scores (P: .006, \u03b7: 0.055), more sexual abuse experiences (P: .009, \u03c6: 0.225), and less relationship satisfaction (P: .017, \u03b7: 0.042). No differences in general self-esteem (P: .169, \u03b7: 0.014) were found in contrast to sexual esteem (P: .021, \u03b7: 0.039). Body self-consciousness (P: .05, r\u00a0=\u20090.242), depression (P: &amp;lt;.001, r\u00a0=\u2009.357), relationship satisfaction (P: .05, r\u00a0=\u2009\u22120.286), and sexual esteem (P: &amp;lt;.001, r\u00a0=\u20090.644) showed significant correlations with sexual dysfunction; and sexual esteem (P: &amp;lt;.001, r\u00a0=\u2009\u22120.475) and use of the combined oral contraceptive pill (P: .05, r\u00a0=\u2009\u22120.270) with dyadic sexual desire. Regression showed the strongest associations (all P: &amp;lt;.001) between sexual esteem and sexual dysfunction and dyadic sexual desire, and between depression and sexual dysfunction with moderate explained variance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Implications<\/jats:title>\n                    <jats:p>Sexual function should be discussed with women with PCOS and psycho-education on the association with sexual esteem and depression given. Other common psychosocial comorbidities in PCOS should be screened. Refer for psychotherapy or a tailormade psychosexual treatment including interventions targeted on sexual esteem and depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Strengths and Limitations<\/jats:title>\n                    <jats:p>Strengths are the broad assessment of psychosocial factors and sexual distress. A weakness is the relatively healthy population possibly underestimating the effect of psychosocial factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Sexual dysfunction and dyadic sexual desire in women with PCOS are predicted by depression and sexual esteem suggesting psychosexual counseling might be helpful.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jsxmed\/qdaf335","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T13:19:39Z","timestamp":1762435179000},"source":"Crossref","is-referenced-by-count":1,"title":["Sexual function in women with Polycystic Ovary Syndrome: the role of psychological factors"],"prefix":"10.1093","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9930-6816","authenticated-orcid":false,"given":"Hester","family":"Pastoor","sequence":"first","affiliation":[{"name":"Erasmus University Medical Center, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology , 3000 CA, Rotterdam ,","place":["the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6084-9207","authenticated-orcid":false,"given":"Ellen M T","family":"Laan","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Centers, Department of Sexology and Psychosomatic Gynecology , 1105 AZ, Amsterdam ,","place":["the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5444-9845","authenticated-orcid":false,"given":"Joop S E","family":"Laven","sequence":"additional","affiliation":[{"name":"Erasmus University Medical Center, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology , 3000 CA, Rotterdam ,","place":["the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Both","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Centers, Department of Sexology and Psychosomatic Gynecology , 1105 AZ, Amsterdam ,","place":["the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,12,7]]},"reference":[{"issue":"9","key":"2026010506162598500_ref1","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1093\/humrep\/dead156","article-title":"Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome","volume":"38","author":"Teede","year":"2023","journal-title":"Hum Reprod"},{"issue":"1","key":"2026010506162598500_ref2","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1038\/s41572-024-00511-3","article-title":"Polycystic ovary syndrome","volume":"10","author":"Stener-Victorin","year":"2024","journal-title":"Nat Rev Dis Primers"},{"issue":"1","key":"2026010506162598500_ref3","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1093\/humrep\/deh098","article-title":"Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)","volume":"19","author":"Rotterdam, E.A.-S.P.C.W.G","year":"2004","journal-title":"Hum Reprod"},{"key":"2026010506162598500_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-03594-5_3-1","volume-title":"Female Reproductive Dysfunction","author":"Louwers","year":"2020"},{"issue":"4","key":"2026010506162598500_ref5","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1016\/j.jsxm.2019.01.313","article-title":"Sexual dysfunction in women with Polycystic Ovary Syndrome: systematic review and meta-analysis","volume":"16","author":"Murgel","year":"2019","journal-title":"J Sex Med"},{"issue":"6","key":"2026010506162598500_ref6","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1016\/j.rbmo.2018.11.030","article-title":"Is polycystic ovary syndrome associated with risk of female sexual dysfunction? 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