{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T06:37:59Z","timestamp":1770619079614,"version":"3.49.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Breast cancer treatment can affect women\u2019s quality of life, body image, and sexual function across multiple dimensions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To assess quality of life, body image, and sexual function in women undergoing breast cancer treatment according to surgical and sociodemographic factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study included 100 women treated at a tertiary hospital. Quality of life was measured using World Health Organization Quality of Life (WHOQOL)-Bref, body image with ERIC scale, and sexual function with Female Sexual Function Index (FSFI). Variables included age, socioeconomic level, relationship status, surgery type (breast-conserving vs. mastectomy), chemotherapy, radiotherapy, and hormone therapy for breast cancer. Associations were examined using Spearman\u2019s correlation and Kruskal\u2013Wallis tests (P\u2009&amp;lt;\u2009.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcomes<\/jats:title>\n                    <jats:p>Quality of life, body image, and sexual function varied significantly by socioeconomic level, relationship status, age, and surgery type.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Women in stable relationships had higher psychological WHOQOL scores. Higher socioeconomic levels correlated with better physical, psychological, and environmental domains. Breast-conserving surgery showed better psychological outcomes than mastectomy. Younger women and those with conservative surgery reported lower ERIC scores in Social Barriers and Appearance\/Sexuality. Among 74 sexually active women, 52 (70%) met FSFI criteria for sexual dysfunction, particularly in Desire, Lubrication, and Dyspareunia, more frequent in women without partners, younger women, and those with mastectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Implications<\/jats:title>\n                    <jats:p>These findings may help clinicians tailor oncologic care to address physical, psychological, and relational dimensions more effectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Strengths &amp; Limitations<\/jats:title>\n                    <jats:p>Strengths include validated instruments and multidimensional assessment; limitations include cross-sectional design, self-reported data, absence of multivariable models, and single-center sample limiting generalizability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Breast cancer treatment affects multiple aspects of women\u2019s well-being, reinforcing the need for comprehensive, patient-centered, multidimensional follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jsxmed\/qdaf395","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T12:43:00Z","timestamp":1767184980000},"source":"Crossref","is-referenced-by-count":0,"title":["Impact of breast cancer treatment on quality of life and sexual health: a multidimensional assessment"],"prefix":"10.1093","volume":"23","author":[{"given":"Walquiria Sayuri","family":"Kuramoto","sequence":"first","affiliation":[{"name":"ABC School of Medicine , Faculty of Medicine, Santo Andr\u00e9, S\u00e3o Paulo, CEP: 09060-870 ,","place":["Brazil"]},{"name":"Department of Academic Studies and Research in Hematology and Oncology (DEPAHOn), ABC School of Medicine , Santo Andr\u00e9, S\u00e3o Paulo, CEP: 09060-870 ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manoela Arruda Tavares","family":"Spada","sequence":"additional","affiliation":[{"name":"ABC School of Medicine , Faculty of Medicine, Santo Andr\u00e9, S\u00e3o Paulo, CEP: 09060-870 ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel De Iracema Gomes","family":"Cubero","sequence":"additional","affiliation":[{"name":"ABC School of Medicine , Faculty of Medicine, Santo Andr\u00e9, S\u00e3o Paulo, CEP: 09060-870 ,","place":["Brazil"]},{"name":"Department of Academic Studies and Research in Hematology and Oncology (DEPAHOn), ABC School of Medicine , Santo Andr\u00e9, S\u00e3o Paulo, CEP: 09060-870 ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Auro","family":"Del Giglio","sequence":"additional","affiliation":[{"name":"ABC School of Medicine , Faculty of Medicine, Santo Andr\u00e9, S\u00e3o Paulo, CEP: 09060-870 ,","place":["Brazil"]},{"name":"Department of Academic Studies and Research in Hematology and Oncology (DEPAHOn), ABC School of Medicine , Santo Andr\u00e9, S\u00e3o Paulo, CEP: 09060-870 ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6895-4914","authenticated-orcid":false,"given":"Luiz Vinicius","family":"de Alcantara Sousa","sequence":"additional","affiliation":[{"name":"Department of Academic Studies and Research in Hematology and Oncology (DEPAHOn), ABC School of Medicine , Santo Andr\u00e9, S\u00e3o Paulo, CEP: 09060-870 ,","place":["Brazil"]},{"name":"Laboratory of Epidemiology and Data Analysis (LEAD), ABC School of Medicine , Santo Andr\u00e9, S\u00e3o Paulo, CEP: 09060-870 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