{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T01:14:24Z","timestamp":1784250864758,"version":"3.55.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Mid-urethral slings (MUS) are widely used to treat urinary incontinence. However, there is limited evidence of their long-term effects on female sexual function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To address this gap, this meta-analysis of randomized controlled trials evaluates changes in Pelvic Organ Prolapse\/Urinary Incontinence Sexual Questionnaire-12 scores at 6, 12, 24, and 36\u00a0months postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We systematically searched PubMed, Cochrane Central, and Embase for studies evaluating the Pelvic Organ Prolapse\/Urinary Incontinence Sexual Questionnaire-12 scores 6, 12, 24, and 36\u00a0months after MUS surgery. We performed a single-arm meta-analysis of single means along with their 95% confidence intervals (CIs) by applying a random-effects model. Subgroup analyses based on MUS types (single-incision, retropubic, and transobturator) were performed to evaluate their specific impacts on sexual function outcomes. Statistical analyses were conducted using Review Manager v5.4 and R v4.3.3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 11 randomized controlled trials comprising a total of 2909 patients, of whom 1747 (60.1%) received a transobturator sling, 505 (17.4%) underwent retropubic sling placement, and 657 (22.6%) were treated with a single-incision sling. At 6\u00a0months, pooled analysis showed an improvement in sexual function, with a mean change from baseline of 4.49 points (95% CI 3.51 to 5.46). By 12\u00a0months, a decrease of 2.68 points (95% CI 0.67 to 4.70) was observed compared with the 6-month assessment. At 24\u00a0months, sexual function also declined slightly of \u22120.52 points (95% CI \u22122.71 to 1.68; P\u2009=\u20090.31), while at 36\u00a0months, there was a slight increase of 0.11 points (95% CI \u22121.95 to 2.17; P\u2009=\u20090.53). Regarding subgroup analysis, no significant differences among sling types, except at 12\u00a0months, when the transobturator group showed greater decline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings indicate that MUS are associated with an initial improvement in sexual function, particularly at 6\u00a0months. However, this improvement is not maintained in long-term follow-up, with scores declining or stabilizing at later time points. These findings are important for patient education and for setting realistic expectations regarding postoperative sexual function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jsxmed\/qdag086","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T12:37:02Z","timestamp":1773751022000},"source":"Crossref","is-referenced-by-count":1,"title":["Impact of mid-urethral sling surgery on sexual function in women with stress urinary incontinence: a meta-analysis of randomized controlled trials"],"prefix":"10.1093","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3765-3931","authenticated-orcid":false,"given":"Giulia Almiron R","family":"Soares","sequence":"first","affiliation":[{"name":"Universidade Metropolitana de Santos , S\u00e3o Paulo 11050-250 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Guimar\u00e3es Campos Roriz","family":"de Amorim","sequence":"additional","affiliation":[{"name":"Indiana University, Department of Urology , Fishers, IN 47405 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna Veiga","family":"Gomes","sequence":"additional","affiliation":[{"name":"Universidade Municipal de S\u00e3o Caetano do Sul , S\u00e3o Caetano do Sul 09521160 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan J S","family":"Godinho","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais , Minas Gerais 31270-901 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0864-2898","authenticated-orcid":false,"given":"Thairo A","family":"Pereira","sequence":"additional","affiliation":[{"name":"University of Rochester Medical Center , Rochester, NY 14609 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6610-4560","authenticated-orcid":false,"given":"Ramzy T","family":"Burns","sequence":"additional","affiliation":[{"name":"Indiana University, Department of Urology , Fishers, IN 47405 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen L","family":"Bernie","sequence":"additional","affiliation":[{"name":"Indiana University, Department of Urology , Fishers, IN 47405 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,9]]},"reference":[{"issue":"3","key":"2026041214285248400_ref1","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/j.eururo.2009.01.007","article-title":"A longitudinal population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in women","volume":"55","author":"Wennberg","year":"2009","journal-title":"Eur Urol"},{"issue":"5","key":"2026041214285248400_ref2","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1067\/S0002-9378(03)00598-2","article-title":"Burden of stress urinary incontinence for community-dwelling women","volume":"189","author":"Fultz","year":"2003","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"2026041214285248400_ref3","doi-asserted-by":"publisher","first-page":"e000206","DOI":"10.1136\/bmjopen-2011-000206","article-title":"Primary and repeat surgical treatment for female pelvic organ prolapse and incontinence in parous women in the UK: a register linkage study","volume":"1","author":"Abdel-Fattah","year":"2011","journal-title":"BMJ Open"},{"issue":"6","key":"2026041214285248400_ref4","first-page":"1306","article-title":"Transobturator urethral suspension: minimally invasive procedure in the treatment of stress urinary incontinence in women","volume":"11","author":"Delorme","year":"2001","journal-title":"Prog Urol"},{"key":"2026041214285248400_ref5","first-page":"212","article-title":"New surgical technique for treatment of stress urinary incontinence TVT-Obturator: new developments and results","volume":"14","author":"de Leval","year":"2005","journal-title":"Surg Technol Int"},{"issue":"2","key":"2026041214285248400_ref6","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/j.urology.2004.09.041","article-title":"Impact of vaginal surgery for stress urinary incontinence on female sexual function: is the use of polypropylene mesh detrimental?","volume":"65","author":"Shah","year":"2005","journal-title":"Urology."},{"issue":"3","key":"2026041214285248400_ref7","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1080\/00926239308404902","article-title":"Prevalence of sexual dysfunction in women: results of a survey study of 329 women in an outpatient gynecological clinic","volume":"19","author":"Rosen","year":"1993","journal-title":"J Sex Marital Ther"},{"issue":"2","key":"2026041214285248400_ref8","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/S0029-7844(01)01749-6","article-title":"Sexual function in women with urinary incontinence and pelvic organ prolapse","volume":"99","author":"Barber","year":"2002","journal-title":"Obstet Gynecol"},{"issue":"6","key":"2026041214285248400_ref9","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1159\/000280537","article-title":"Sexual dysfunction associated with urinary incontinence","volume":"35","author":"Sutherst","year":"1980","journal-title":"Urol Int"},{"issue":"2","key":"2026041214285248400_ref10","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/S0090-4295(00)00569-6","article-title":"Sexual function after vaginal surgery for stress incontinence: results of a mailed questionnaire","volume":"56","author":"Lemack","year":"2000","journal-title":"Urology."},{"issue":"10","key":"2026041214285248400_ref11","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1111\/aogs.12466","article-title":"Sexual function in women before and after tension-free vaginal tape operation for stress urinary incontinence","volume":"93","author":"Glavind","year":"2014","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"9","key":"2026041214285248400_ref12","doi-asserted-by":"publisher","first-page":"1498","DOI":"10.1016\/j.jsxm.2016.07.006","article-title":"The impact of midurethral sling surgery on sexual activity and function in women with stress urinary incontinence","volume":"13","author":"Mengerink","year":"2016","journal-title":"J Sex Med"},{"issue":"3","key":"2026041214285248400_ref13","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1007\/s00192-003-1063-2","article-title":"A short form of the Pelvic Organ Prolapse\/Urinary Incontinence Sexual Questionnaire (PISQ-12)","volume":"14","author":"Rogers","year":"2003","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"1","key":"2026041214285248400_ref14","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.ejogrb.2009.05.016","article-title":"Validation of the short form of the Pelvic Organ Prolapse\/Urinary Incontinence Sexual Questionnaire (PISQ-12) in a Turkish population","volume":"146","author":"Cam","year":"2009","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2026041214285248400_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/9780470712184","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions","author":"Higgins","year":"2008","edition":"1st ed."},{"key":"2026041214285248400_ref16","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ."},{"issue":"47","key":"2026041214285248400_ref17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3310\/BTSA6148","article-title":"Single-incision mini-slings versus standard synthetic mid-urethral slings for surgical treatment of stress urinary incontinence in women: the SIMS RCT","volume":"26","author":"Abdel-Fattah","year":"2022","journal-title":"Health Technol Assess"},{"issue":"9","key":"2026041214285248400_ref18","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1007\/s00192-019-04004-w","article-title":"Adjustable mini-sling compared with conventional mid-urethral slings in women with urinary incontinence: a 3-year follow-up of a randomized controlled trial","volume":"30","author":"Alexandridis","year":"2019","journal-title":"Int Urogynecol J"},{"issue":"2","key":"2026041214285248400_ref19","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1097\/AOG.0000000000003648","article-title":"Effect of surgery for stress incontinence on female sexual function","volume":"135","author":"Glass Clark","year":"2020","journal-title":"Obstet Gynecol"},{"key":"2026041214285248400_ref20","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.ejogrb.2018.09.032","article-title":"TVT Abbrevo and Miniarc suburethral sling in women with stress urinary incontinence: a randomized controlled trial","volume":"230","author":"Melendez-Munoz","year":"2018","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"11","key":"2026041214285248400_ref21","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1007\/s00192-010-1197-y","article-title":"Prospective randomized trial comparing synthetic vs biological out-in transobturator tape: a mean 3-year follow-up study","volume":"21","author":"Paparella","year":"2010","journal-title":"Int Urogynecol J"},{"issue":"2","key":"2026041214285248400_ref22","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/s00192-011-1461-9","article-title":"Sexual function following retropubic TVT and transobturator Monarc sling in women with intrinsic sphincter deficiency: a multicentre prospective study","volume":"23","author":"De Souza","year":"2012","journal-title":"Int Urogynecol J"},{"key":"2026041214285248400_ref23","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.urology.2017.06.033","article-title":"The efficiency and safety of tension-free vaginal tape (TVT) Abbrevo procedure versus TVT exact in normal weight and overweight patients affected by stress urinary incontinence","volume":"110","author":"Sun","year":"2017","journal-title":"Urology."},{"issue":"6","key":"2026041214285248400_ref24","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1097\/GME.0000000000000119","article-title":"Outcome and sexual function after transobturator tape procedure versus tension-free vaginal tape SECUR: a randomized controlled trial","volume":"21","author":"Tang","year":"2014","journal-title":"Menopause."},{"issue":"2","key":"2026041214285248400_ref25","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1016\/j.jmig.2012.11.008","article-title":"Tension-free vaginal tape-O and -SECUR for the treatment of stress urinary incontinence: a 36-month follow-up single-blind, double-arm, randomized study","volume":"20","author":"Tommaselli","year":"2013","journal-title":"J Minim Invasive Gynecol"},{"issue":"4","key":"2026041214285248400_ref26","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1007\/s00192-019-04077-7","article-title":"TVT-O vs TVT-Abbrevo for stress urinary incontinence treatment in women: a randomized trial","volume":"31","author":"Zullo","year":"2020","journal-title":"Int Urogynecol J"},{"issue":"5","key":"2026041214285248400_ref27","doi-asserted-by":"publisher","first-page":"421.e1","DOI":"10.1016\/j.ajog.2012.06.053","article-title":"Urinary incontinence treatment network. Sexual activity and function in women more than 2 years after midurethral sling placement","volume":"207","author":"Zyczynski","year":"2012","journal-title":"Am J Obstet Gynecol"},{"issue":"5 Suppl 2","key":"2026041214285248400_ref28","doi-asserted-by":"publisher","first-page":"S120","DOI":"10.5489\/cuaj.12197","article-title":"Complications of midurethral slings and their management","volume":"6","author":"Nitti","year":"2012","journal-title":"Can Urol Assoc J"},{"issue":"8","key":"2026041214285248400_ref29","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1002\/nau.20840","article-title":"Patient satisfaction with stress incontinence surgery","volume":"29","author":"Burgio","year":"2010","journal-title":"Neurourol Urodyn"},{"issue":"1 Pt 1","key":"2026041214285248400_ref30","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1111\/j.1743-6109.2009.01613.x","article-title":"Who\u2019s afraid of the G-spot?","volume":"7","author":"Jannini","year":"2010","journal-title":"J Sex Med"},{"issue":"5","key":"2026041214285248400_ref31","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1038\/ijir.2008.23","article-title":"Women's sexual function and dysfunction: current uncertainties, future directions","volume":"20","author":"Basson","year":"2008","journal-title":"Int J Impot Res"},{"issue":"2","key":"2026041214285248400_ref32","doi-asserted-by":"publisher","first-page":"e84","DOI":"10.1016\/j.esxm.2016.12.001","article-title":"A meta-analysis detailing overall sexual function and orgasmic function in women undergoing midurethral sling surgery for stress incontinence","volume":"5","author":"Szell","year":"2017","journal-title":"Sex Med"},{"issue":"4","key":"2026041214285248400_ref33","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1007\/s00192-005-0035-3","article-title":"Anatomical study of the obturator foramen and dorsal nerve of the clitoris and their relationship to minimally invasive slings","volume":"17","author":"Achtari","year":"2006","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"key":"2026041214285248400_ref34","doi-asserted-by":"publisher","first-page":"387","DOI":"10.2147\/IJWH.S158913","article-title":"Current treatment options for postmenopausal vaginal atrophy","volume":"10","author":"Naumova","year":"2018","journal-title":"Int J Women's Health"},{"key":"2026041214285248400_ref35","doi-asserted-by":"publisher","first-page":"307","DOI":"10.2147\/IJWH.S52555","article-title":"Reviewing the options for local estrogen treatment of vaginal atrophy","volume":"6","author":"Lindahl","year":"2014","journal-title":"Int J Women's Health"},{"issue":"10","key":"2026041214285248400_ref36","doi-asserted-by":"publisher","first-page":"615","DOI":"10.3390\/medicina55100615","article-title":"Vaginal health in menopausal women","volume":"55","author":"Alvisi","year":"2019","journal-title":"Medicina (Kaunas)"},{"key":"2026041214285248400_ref37","volume-title":"StatPearls [Internet]","author":"Carlson","year":"2024"}],"container-title":["The Journal of Sexual Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/23\/5\/qdag086\/68019789\/qdag086.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/23\/5\/qdag086\/68019789\/qdag086.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T18:28:58Z","timestamp":1776018538000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jsm\/article\/doi\/10.1093\/jsxmed\/qdag086\/8650589"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,9]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,4,9]]}},"URL":"https:\/\/doi.org\/10.1093\/jsxmed\/qdag086","relation":{},"ISSN":["1743-6095","1743-6109"],"issn-type":[{"value":"1743-6095","type":"print"},{"value":"1743-6109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,5]]},"published":{"date-parts":[[2026,4,9]]},"article-number":"qdag086"}}