{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T08:59:35Z","timestamp":1791536375647,"version":"4.3.4"},"reference-count":59,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011015","name":"International Society of Travel Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011015","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Older persons may suffer more from travel-related health problems because of ageing and underlying chronic disorders. Knowledge on who is more likely to have these health problems helps to tailor travel health advice more specifically. This study aimed to determine predictors of travel-related morbidity in older travellers by assessing their pre-travel characteristics and performance using physical and cognitive functioning tests.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Multicentre prospective cohort study among older travellers (\u226560\u00a0years) who consulted one of the participating Dutch travel clinics. Handgrip strength and cognitive performance were measured pre-travel. Participants completed questionnaires before departure and 1 and 4 weeks after return. A diary recorded health complaints during travel until 2-week post-travel.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In total, 477 travellers completed the study (follow-up rate of 97%). Participants\u2019 median age was 66\u00a0years. The most visited regions were South-East Asia (34%) and South Asia (14%). Median travel duration was 19\u00a0days. Polypharmacy (\u22655 medications per day) was not uncommon (16%). The median Charlson Comorbidity Index (CCI) score was 0. Self-reported travel-related infectious diseases concerned primarily respiratory tract infections (21%) and gastroenteritis (10%) whereas non-infectious complaints were injuries (13%), peripheral edema (12%) and dehydration (3%). Medical assistance was sought by 18%, mostly post-travel from their general practitioner (87%). Self-reported physical and mental health-related quality of life significantly improved during and after travel. Predictors for an increased risk of travel-related morbidity were higher CCI score, more travel experience, longer travel duration, higher number of daily medications, visiting northern Africa or South-East and East Asia, and phone and social media use.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Older Dutch travellers are generally fit, well-prepared and suffer not only from common infectious health problems, but also from injuries. Travel improved their self-perceived health. The predictors could be used to identify the more at-risk older traveller and to decrease travel-related morbidity by optimizing pre-travel advice.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jtm\/taaa216","type":"journal-article","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T20:06:08Z","timestamp":1605643568000},"source":"Crossref","is-referenced-by-count":11,"title":["Predicting morbidity in older travellers during a short-term stay in the tropics: the ELDEST study"],"prefix":"10.1093","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4067-7027","authenticated-orcid":false,"given":"Jessica A","family":"Vlot","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marissa G D","family":"Vive","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henricus J","family":"Brockhoff","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Municipal Health Service, Westeinde 128, 2512 HE The Hague, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter J J","family":"van Genderen","sequence":"additional","affiliation":[{"name":"Harbour Hospital and Institute for Tropical Diseases, currently working on Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Christine E","family":"Trompenaars","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Municipal Health Service, Schiedamsedijk 95, 3011 EN Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E","family":"van Steenbergen","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands"},{"name":"Centre for Infectious Disease Control, Netherlands Institute for Public Health and Environment, Antonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardus G","family":"Visser","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,11,19]]},"reference":[{"key":"2021010706003144000_ref1","volume-title":"International Travel and Health 2012","author":"World Health Organization"},{"key":"2021010706003144000_ref2","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1093\/milmed\/162.3.172","article-title":"Epidemiology, preventive services, and illnesses of international travelers","volume":"162","author":"Scoville","year":"1997","journal-title":"Mil Med"},{"key":"2021010706003144000_ref3","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2310\/7060.2000.00075","article-title":"Health problems in a large cohort of Americans traveling to developing countries","volume":"7","author":"Hill","year":"2000","journal-title":"J Travel Med"},{"key":"2021010706003144000_ref4","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.tmaid.2015.10.001","article-title":"The elderly, the young and the pregnant traveler - 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