{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:13:21Z","timestamp":1787163201861,"version":"build-2736575974"},"reference-count":66,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T00:00:00Z","timestamp":1625529600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Travellers\u2019 diarrhoea (TD) is the most common clinical syndrome affecting travellers. This narrative review summarizes key discoveries reported in the last two years related to TD and suggests areas for future research.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A PubMed literature search was conducted for novel data in TD research published between 12 January 2018 and 12 January 2020. Inclusion was based on contribution to epidemiology, aetiology, diagnostics, management and long-term consequences and relevance to public health, discovery and clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The initial literature search yielded 118 articles. We retrieved 72 and reviewed 31 articles for inclusion. The findings support our understanding that TD incidence varies by traveller group and environment with students and military-travel remaining moderately high risk, and control of food and water in mass gathering events remain an important goal. The growth of culture-independent testing has led to a continued detection of previously known pathogens, but also an increased detection frequency of norovirus. Another consequence is the increase in multi-pathogen infections, which require consideration of clinical, epidemiological and diagnostic data. Fluoroquinolone resistant rates continue to rise. New data on non-absorbable antibiotics continue to emerge, offering a potential alternative to current recommendations (azithromycin and fluoroquinolones), but are not recommended for febrile diarrhoea or dysentery or regions\/itineraries where invasive pathogens are likely to cause illness. Recent studies investigated the interaction of the microbiome in TD prevention and consequences, and while discriminating features were identified, much uncertainty remains. The prevalence of extended-spectrum beta-lactamase\u2013producing Enterobacteriaceae (ESBL-PE) acquisition and carriage is increasing. Finally, continued research documents the post-infectious consequences, whereas mechanisms of reactive arthritis and post-infectious IBS necessitate further investigation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Globally, TD remains an important travel health issue and advances in our understanding continue. More research is needed to mitigate risk factors where possible and develop risk-based management strategies to reduce antibiotic usage and its attendant consequences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jtm\/taab099","type":"journal-article","created":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T07:48:16Z","timestamp":1625125696000},"source":"Crossref","is-referenced-by-count":34,"title":["What\u2019s new in travellers\u2019 diarrhoea: updates on epidemiology, diagnostics, treatment and long-term consequences"],"prefix":"10.1093","volume":"29","author":[{"given":"Audrey V","family":"Adler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailee R","family":"Ciccotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spencer J H","family":"Trivitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland C J","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S","family":"Riddle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,7,6]]},"reference":[{"key":"2022011714502285000_ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jtm\/tax007","article-title":"Global travel patterns: an overview","volume":"24","author":"Glaesser","year":"2017","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref2","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1001\/jama.2014.17006","article-title":"Traveler\u2019s diarrhea a clinical review","volume":"313","author":"Steffen","year":"2015","journal-title":"J Am Med Assoc"},{"key":"2022011714502285000_ref3","doi-asserted-by":"crossref","first-page":"38","DOI":"10.2174\/1872213X13666190514105054","article-title":"Travelers\u2019 diarrhea: a clinical review","volume":"13","author":"Leung","year":"2019","journal-title":"Recent Pat Inflamm Allergy Drug Discov"},{"key":"2022011714502285000_ref4","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1708-8305.2008.00189.x","article-title":"Economic aspects of travelers\u2019 diarrhea","volume":"15","author":"Wang","year":"2008","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jtm\/taaa155","article-title":"Use of face masks and other personal preventive measures by Hajj pilgrims and their impact on health problems during the Hajj","volume":"27","author":"Alasmari","year":"2020","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref6","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s10096-020-04018-z","article-title":"Gastrointestinal symptoms and the acquisition of enteric pathogens in Hajj pilgrims: a 3-year prospective cohort study","volume":"40","author":"Hoang","year":"2020","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2022011714502285000_ref7","first-page":"274","article-title":"Health hazards and risk factors in the 1406 (1986) Hajj season","volume":"9","author":"Ghanzawi","year":"1988","journal-title":"Saudi Med J"},{"key":"2022011714502285000_ref8","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/S0140-6736(19)30501-X","article-title":"Mass gatherings medicine: public health issues arising from mass gathering religious and sporting events","volume":"393","author":"Memish","year":"2019","journal-title":"Lancet"},{"key":"2022011714502285000_ref9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11908-018-0650-9","article-title":"Infectious diseases and mass gatherings","volume":"20","author":"Hoang","year":"2018","journal-title":"Curr Infect Dis Rep"},{"key":"2022011714502285000_ref10","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/S0140-6736(14)60381-0","article-title":"Hajj: infectious disease surveillance and control","volume":"383","author":"Memish","year":"2014","journal-title":"Lancet"},{"key":"2022011714502285000_ref11","doi-asserted-by":"crossref","first-page":"101779","DOI":"10.1016\/j.tmaid.2020.101779","article-title":"Travel preparation and health risks in Dutch and Belgian medical students during an elective in low- or middle-income countries: a prospective self-reporting cohort study","volume":"37","author":"Vlot","year":"2020","journal-title":"Travel Med Infect Dis"},{"key":"2022011714502285000_ref12","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.ijid.2020.08.075","article-title":"Risk factors for symptoms of infection and microbial carriage among French medical students abroad","volume":"100","author":"Dao","year":"2020","journal-title":"Int J Infect Dis"},{"key":"2022011714502285000_ref13","first-page":"538","article-title":"Acute diarrhea in North American students after relocation to Israel: a pilot study","volume":"21","author":"Meltzer","year":"2019","journal-title":"Isr Med Assoc J"},{"key":"2022011714502285000_ref14","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.4269\/ajtmh.18-0353","article-title":"A comparison of pretravel health care, travel-related exposures, and illnesses among pediatric and adult U.S. Military beneficiaries","volume":"100","author":"Ashley","year":"2019","journal-title":"Am J Trop Med Hyg"},{"key":"2022011714502285000_ref15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40794-018-0077-1","article-title":"Travelers\u2019 diarrhea: update on the incidence, etiology and risk in military and similar populations - 1990-2005 versus 2005-2015, does a decade make a difference?","volume":"5","author":"Olson","year":"2019","journal-title":"Trop Dis Travel Med Vaccines."},{"key":"2022011714502285000_ref16","doi-asserted-by":"crossref","first-page":"4","DOI":"10.7205\/MILMED-D-17-00064","article-title":"Travelers\u2019 diarrhea: an update on the incidence, etiology, and risk in military deployments and similar travel populations","volume":"182","author":"Porter","year":"2017","journal-title":"Mil Med"},{"key":"2022011714502285000_ref17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0236703","article-title":"Epidemiology and associated microbiota changes in deployed military personnel at high risk of traveler\u2019s diarrhea","volume":"15","author":"Walters","year":"2020","journal-title":"PLoS One"},{"key":"2022011714502285000_ref18","volume-title":"Diarrhea and Associated Illness Characteristics and Risk Factors Among British Active Duty Service Members at Askari Storm Training Exercise, , Nanyuki, Kenya, January\u2013June 2014","author":"Burns"},{"key":"2022011714502285000_ref19","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/j.1708-8305.2006.00020.x","article-title":"Self-reported description of diarrhea among military populations in operations Iraqi freedom and enduring freedom","volume":"13","author":"Putnam","year":"2006","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref20","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/tmi.13183","article-title":"Locals get travellers\u2019 diarrhoea too: risk factors for diarrhoeal illness and pathogenic Escherichia coli infection across an urban-rural gradient in Ecuador","volume":"24","author":"Smith","year":"2019","journal-title":"Trop Med Int Heal"},{"key":"2022011714502285000_ref21","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.mcna.2015.08.017","article-title":"Traveler\u2019s diarrhea","volume":"100","author":"Giddings","year":"2016","journal-title":"Med Clin North Am"},{"key":"2022011714502285000_ref22","doi-asserted-by":"crossref","first-page":"S531","DOI":"10.1086\/432947","article-title":"Looking for evidence that personal hygiene precautions prevent traveler\u2019s diarrhea","volume":"41","author":"Shlim","year":"2005","journal-title":"Clin Infect Dis"},{"key":"2022011714502285000_ref23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40794-018-0076-2","article-title":"Impact of pre-travel consultation on clinical management and outcomes of travelers\u2019 diarrhea: a retrospective cohort study","volume":"4","author":"Tan","year":"2018","journal-title":"Trop Dis Travel Med Vaccines"},{"key":"2022011714502285000_ref24","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1093\/jtm\/taw090","article-title":"Resistant pathogens as causes of traveller\u2019s diarrhea globally and impact(s) on treatment failure and recommendations","volume":"24","author":"Tribble","year":"2017","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref25","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.4269\/ajtmh.20-0053","article-title":"A multisite network assessment of the epidemiology and etiology of acquired diarrhea among U.S. military and western travelers (global travelers\u2019 diarrhea study): a principal role of norovirus among travelers with gastrointestinal illness","volume":"103","author":"Ashbaugh","year":"2020","journal-title":"Am J Trop Med Hyg"},{"key":"2022011714502285000_ref26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40794-019-0085-9","article-title":"Epidemiology and etiology of traveler\u2019s diarrhea in Bangkok, Thailand, a case-control study","volume":"5","author":"Bodhidatta","year":"2019","journal-title":"Trop Dis Travel Med Vaccines"},{"key":"2022011714502285000_ref27","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1136\/archdischild-2017-314327","article-title":"Multiplex PCR reveals a high prevalence of multiple pathogens in traveller\u2019s diarrhoea in children","volume":"104","author":"Pouletty","year":"2019","journal-title":"Arch Dis Child"},{"key":"2022011714502285000_ref28","doi-asserted-by":"crossref","first-page":"101706","DOI":"10.1016\/j.tmaid.2020.101706","article-title":"Risk factors for different intestinal pathogens among patients with traveler\u2019s diarrhea: a retrospective analysis at a German travel clinic (2009\u20132017)","volume":"37","author":"Brehm","year":"2020","journal-title":"Travel Med Infect Dis"},{"key":"2022011714502285000_ref29","doi-asserted-by":"crossref","first-page":"101696","DOI":"10.1016\/j.tmaid.2020.101696","article-title":"Aetiology of traveller\u2019s diarrhea: a nested case-control study","volume":"37","author":"Schaumburg","year":"2020","journal-title":"Travel Med Infect Dis"},{"key":"2022011714502285000_ref30","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jiac.2020.08.009","article-title":"Spectrum of enteropathogens in cases of traveler\u2019s diarrhea that were detected using the FilmArray GI panel: new epidemiology in Japan","volume":"27","author":"Kutsuna","year":"2021","journal-title":"J Infect Chemother"},{"key":"2022011714502285000_ref31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jtm\/taz054","article-title":"Traveler\u2019s diarrhea in Nepal\u2014changes in etiology and antimicrobial resistance","volume":"26","author":"Murphy","year":"2019","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref32","doi-asserted-by":"crossref","first-page":"ofaa543","DOI":"10.1093\/ofid\/ofaa543","article-title":"Acquisition and long-term carriage of multidrug-resistant organisms in US international travelers","volume":"7","author":"Worby","year":"2020","journal-title":"Open Forum Infect Dis"},{"key":"2022011714502285000_ref33","doi-asserted-by":"crossref","first-page":"101855","DOI":"10.1016\/j.tmaid.2020.101855","article-title":"Clinical aspects of heat-labile and heat-stable toxin-producing enterotoxigenic Escherichia coli: a prospective study among Finnish travellers","volume":"38","author":"Turunen","year":"2020","journal-title":"Travel Med Infect Dis"},{"key":"2022011714502285000_ref34","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1128\/CMR.00112-13","article-title":"Clinical manifestations of enteroaggregative Escherichia coli","volume":"27","author":"Jensen","year":"2014","journal-title":"Clin Microbiol Rev"},{"key":"2022011714502285000_ref35","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0140-6736(13)60844-2","article-title":"Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study","volume":"382","author":"Kotloff","year":"2013","journal-title":"Lancet"},{"key":"2022011714502285000_ref36","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.cmi.2016.02.011","article-title":"Prospective study of pathogens in asymptomatic travellers and those with diarrhoea: aetiological agents revisited","volume":"22","author":"L\u00e4\u00e4veri","year":"2016","journal-title":"Clin Microbiol Infect"},{"key":"2022011714502285000_ref37","doi-asserted-by":"crossref","first-page":"200","DOI":"10.3389\/fcimb.2020.00200","article-title":"Genetic and virulence profiles of enteroaggregative Escherichia coli (EAEC) isolated from deployed military personnel (dmp) with travelers\u2019 diarrhea","volume":"10","author":"Petro","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"key":"2022011714502285000_ref38","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.micpath.2018.12.030","article-title":"Occurrence of putative virulence-related genes, aatA, aggR and aaiC, of enteroaggregative Escherichia coli (EAEC) among adults with travelers\u2019 diarrhea acquired in Guatemala and Mexico","volume":"128","author":"Bamidele","year":"2019","journal-title":"Microb Pathog"},{"key":"2022011714502285000_ref39","doi-asserted-by":"crossref","first-page":"101362","DOI":"10.1016\/j.tmaid.2018.12.005","article-title":"Risk of acquisition of human diarrhoeagenic Escherichia coli virulence genes in intercontinental travellers: a prospective, multi-centre study","volume":"31","author":"Hattem","year":"2019","journal-title":"Travel Med Infect Dis"},{"key":"2022011714502285000_ref40","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1093\/cid\/ciy915","article-title":"Epidemiologic and genotypic distribution of noroviruses among children with acute diarrhea and healthy controls in a low-income rural setting","volume":"69","author":"Hossain","year":"2019","journal-title":"Clin Infect Dis"},{"key":"2022011714502285000_ref41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12879-018-3461-6","article-title":"Estimating the incidence of norovirus acute gastroenteritis among US and European international travelers to areas of moderate to high risk of traveler\u2019s diarrhea: a prospective cohort study protocol","volume":"18","author":"Lindsay","year":"2018","journal-title":"BMC Infect Dis"},{"key":"2022011714502285000_ref42","doi-asserted-by":"crossref","first-page":"S63","DOI":"10.1093\/jtm\/tax026","article-title":"Guidelines for the prevention and treatment of travelers\u2019 diarrhea: a graded expert panel report","volume":"24","author":"Riddle","year":"2017","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref43","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1708-8305.2010.00475.x","article-title":"Travelers\u2019 diarrhea in Nepal: an update on the pathogens and antibiotic resistance","volume":"18","author":"Pandey","year":"2011","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref44","doi-asserted-by":"crossref","DOI":"10.1007\/s11908-020-0717-2","article-title":"Travel, diarrhea, antibiotics, antimicrobial resistance and practice guidelines\u2014a holistic approach to a health conundrum","volume":"22","author":"Riddle","year":"2020","journal-title":"Curr Infect Dis Rep"},{"key":"2022011714502285000_ref45","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01745-18","article-title":"Emergence of resistance to quinolones and -lactam antibiotics in enteroaggregative and enterotoxigenic Escherichia coli causing traveler\u2019s diarrhea","volume":"63","author":"Guiral","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"2022011714502285000_ref46","doi-asserted-by":"crossref","first-page":"e0225800","DOI":"10.1371\/journal.pone.0225800","article-title":"Quinolone nonsusceptibility among enteric pathogens isolated from international travelers - foodborne diseases active surveillance network (FoodNet) and national antimicrobial monitoring system (NARMS), 10 United States sites, 2004 - 2014. Duse AG, ed","volume":"14","author":"Grass","year":"2019","journal-title":"PLoS One"},{"key":"2022011714502285000_ref47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ofid\/ofz187","article-title":"A comparison of stool enteropathogen detection by semiquantitative PCR in adults with acute travelers\u2019 diarrhea before and 3 weeks after successful antibiotic treatment","volume":"6","author":"Tisdale","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"2022011714502285000_ref48","doi-asserted-by":"crossref","first-page":"ofz162","DOI":"10.1093\/ofid\/ofz162","article-title":"Clinical yield of a molecular diagnostic panel for enteric pathogens in adult outpatients with diarrhea and validation of guidelines-based criteria for testing","volume":"6","author":"Clark","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"2022011714502285000_ref49","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1186\/s12876-020-01394-w","article-title":"Use of BioFire FilmArray gastrointestinal PCR panel associated with reductions in antibiotic use, time to optimal antibiotics, and length of stay","volume":"20","author":"Torres-Miranda","year":"2020","journal-title":"BMC Gastroenterol"},{"key":"2022011714502285000_ref50","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1186\/s13104-020-05340-7","article-title":"Performance characteristics of a quantitative PCR assay on repository stool specimens and smeared filter-paper cards","volume":"13","author":"Tisdale","year":"2020","journal-title":"BMC Res Notes"},{"key":"2022011714502285000_ref51","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/milmed\/usz182","article-title":"Deployment infectious disease threats: IDCRP initiatives and vision forward","volume":"184","author":"Lalani","year":"2019","journal-title":"Mil Med"},{"key":"2022011714502285000_ref52","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jtm\/taz014","article-title":"Rifamycin SV-MMX\u00ae as the recommended self-treatment for moderate to severe travellers\u2019 diarrhoea: reply","volume":"26","author":"Steffen","year":"2019","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref53","doi-asserted-by":"crossref","first-page":"4491","DOI":"10.3748\/wjg.v23.i25.4491","article-title":"Eubiotic properties of rifaximin: disruption of the traditional concepts in gut microbiota modulation","volume":"23","author":"Ponziani","year":"2017","journal-title":"World J Gastroenterol"},{"key":"2022011714502285000_ref54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jtm\/tay137","article-title":"Antibiotics for travellers\u2019 diarrhoea on trial\u2014is there a potential role for rifamycin SV?","volume":"26","author":"Riddle","year":"2019","journal-title":"J Travel Med"},{"key":"2022011714502285000_ref55","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1093\/cid\/cix693","article-title":"Trial evaluating ambulatory therapy of travelers\u2019 diarrhea (TrEAT TD) study: a randomized controlled trial comparing 3 single-dose antibiotic regimens with loperamide","volume":"65","author":"Riddle","year":"2017","journal-title":"Clin Infect Dis"},{"key":"2022011714502285000_ref56","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00066-18","article-title":"Phage therapy in the postantibiotic era","volume":"32","author":"Gordillo Altamirano","year":"2019","journal-title":"Clin Microbiol Rev"},{"key":"2022011714502285000_ref57","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2020.00200","article-title":"Genetic and virulence profiles of enteroaggregative Escherichia coli (EAEC) isolated from deployed military personnel (DMP) with travelers\u2019 diarrhea","volume":"10","author":"Petro","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"key":"2022011714502285000_ref58","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1099\/jmm.0.001162","article-title":"Myoviridae phage PDX kills enteroaggregative Escherichia coli without human microbiome dysbiosis","volume":"69","author":"Cepko","year":"2020","journal-title":"J Med Microbiol"},{"key":"2022011714502285000_ref59","article-title":"Lasso peptide microcin J25 effectively enhances gut barrier function and modulates inflammatory response in an enterotoxigenic Escherichia coli-challenged mouse model","author":"Ding","journal-title":"Int J Mol Sci Artic"},{"key":"2022011714502285000_ref60","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.4269\/ajtmh.20-0241","article-title":"Doxycycline malaria prophylaxis impact on risk of travelers\u2019 diarrhea among international travelers","volume":"103","author":"Lago","year":"2020","journal-title":"Am J Trop Med Hyg"},{"key":"2022011714502285000_ref61","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1080\/19490976.2018.1564431","article-title":"The intestinal microbiota predisposes to traveler\u2019s diarrhea and to the carriage of multidrug-resistant Enterobacteriaceae after traveling to tropical regions","volume":"10","author":"Leo","year":"2019","journal-title":"Gut Microbes"},{"key":"2022011714502285000_ref62","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1136\/annrheumdis-2019-216736","article-title":"Reactive arthritis and other musculoskeletal symptoms associated with acquisition of diarrhoeagenic Escherichia coli (DEC)","volume":"79","author":"Tuompo","year":"2020","journal-title":"Ann Rheum Dis"},{"key":"2022011714502285000_ref63","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/nmo.13542","article-title":"Prospective study evaluating immune-mediated mechanisms and predisposing factors underlying persistent postinfectious abdominal complaints","volume":"31","author":"Florens","year":"2019","journal-title":"Neurogastroenterol Motil"},{"key":"2022011714502285000_ref64","doi-asserted-by":"crossref","first-page":"101521","DOI":"10.1016\/j.tmaid.2019.101521","article-title":"Intestinal colonization with extended-spectrum beta-lactamase producing enterobacterales (ESBL-PE) during long distance travel: a cohort study in a German travel clinic (2016\u20132017)","volume":"33","author":"Meurs","year":"2020","journal-title":"Travel Med Infect Dis"},{"key":"2022011714502285000_ref65","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3109\/00365540903493715","article-title":"Extended-spectrum beta-lactamase-producing Escherichia coli in patients with travellers\u2019 diarrhoea","volume":"42","author":"Tham","year":"2010","journal-title":"Scand J Infect Dis"},{"key":"2022011714502285000_ref66","doi-asserted-by":"crossref","first-page":"e01585","DOI":"10.1128\/AAC.01585-20","article-title":"A cross-sectional cohort study of extended-spectrum-beta- lactamase-producing enterobacterales in patients with traveler\u2019s diarrhea","volume":"64","author":"Ljungquist","year":"2020","journal-title":"Antimicrob Agents Chemother"}],"container-title":["Journal of Travel Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jtm\/advance-article-pdf\/doi\/10.1093\/jtm\/taab099\/38873890\/taab099.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jtm\/article-pdf\/29\/1\/taab099\/42208641\/taab099.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jtm\/article-pdf\/29\/1\/taab099\/42208641\/taab099.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T09:52:11Z","timestamp":1642413131000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jtm\/article\/doi\/10.1093\/jtm\/taab099\/6316240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,6]]},"references-count":66,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,7,6]]},"published-print":{"date-parts":[[2022,1,17]]}},"URL":"https:\/\/doi.org\/10.1093\/jtm\/taab099","relation":{},"ISSN":["1195-1982","1708-8305"],"issn-type":[{"value":"1195-1982","type":"print"},{"value":"1708-8305","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,1]]},"published":{"date-parts":[[2021,7,6]]},"article-number":"taab099"}}