{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T13:26:09Z","timestamp":1793625969935,"version":"4.5.1"},"reference-count":21,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["U01CK000632-04"],"award-info":[{"award-number":["U01CK000632-04"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011015","name":"International Society of Travel Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011015","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011094","name":"Public Health Agency of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011094","id-type":"DOI","asserted-by":"publisher"}]},{"name":"GeoSentinel Foundation"},{"name":"CIBERINFEC-Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas","id":[{"id":"https:\/\/ror.org\/02g87qh62","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Italian Ministry of Health with Ricerca corrente"},{"name":"Linea 1 funds to IRCCS Sacro Cuore Don Calabria"},{"name":"U.S. CDC Cooperative Agreement"},{"name":"GeoSentinel Network"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Antimicrobial resistance (AMR) is a major global health threat, and Staphylococcus aureus is among the leading contributors to the global AMR-attributable disease burden. Data on the clinical presentation and antimicrobial susceptibility patterns of S. aureus infections in returning travellers remain scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We described the clinical presentation, travel characteristics, and antimicrobial susceptibility of travellers and migrants diagnosed with S. aureus infection through the GeoSentinel network between January 2014 and December 2022. Because no consensus definition exists for travel-associated infections, we included all cases recorded in the GeoSentinel database as travel-associated. We evaluated patients during travel or after return. Antimicrobial susceptibility testing (AST) was performed according to routine laboratory practice at participating sites.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We retrieved 740 travellers and migrants with S. aureus infection diagnosed at 50 GeoSentinel sites. Four hundred thirty-eight (59.2%) were male, and the median age was 32\u00a0years (IQR 23-48). The most frequently visited regions were Southeast Asia, sub-Saharan Africa and South-Central Asia. Most patients presented after travel (576\/740; 77.8%). Skin and soft tissue infections (SSTI) were the predominant diagnosis (670\/740; 90.5%), and most patients were managed as outpatients (579\/740; 78.2%). Overall, 406\/740 (54.9%) isolates showed resistance or reduced susceptibility to at least one antimicrobial class, including methicillin (224\/656; 34.1%), lincosamides (144\/627; 23.0%) and trimethoprim-sulfamethoxazole (129\/597; 21.6%). Demographic characteristics and hospitalization frequency were similar between patients with methicillin-susceptible S. aureus and methicillin-resistant S. aureus infections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Most S. aureus infections in international travellers presented as SSTIs and were managed in outpatient settings. Resistance or reduced susceptibility to at least one antimicrobial class was common, with one-third of isolates identified as methicillin-resistant. These findings support the importance of AST to guide management of SSTIs in internationally mobile populations and reinforce the need for standardized definitions of travel-associated bacterial infections and continued global surveillance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jtm\/taag091","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T11:40:54Z","timestamp":1792496454000},"source":"Crossref","is-referenced-by-count":0,"title":["Travel-associated\n                    <i>Staphylococcus aureus<\/i>\n                    infections: a global perspective from the GeoSentinel surveillance network"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1226-8616","authenticated-orcid":false,"given":"Clara","family":"Crespillo-And\u00fajar","sequence":"first","affiliation":[{"name":"National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ram\u00f3n y Cajal University Hospital-IRYCIS , Madrid ,","place":["Spain"]},{"name":"CIBERINFEC, Instituto de Salud Carlos III , Madrid ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0336-7767","authenticated-orcid":false,"given":"Francesca F","family":"Norman","sequence":"additional","affiliation":[{"name":"National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ram\u00f3n y Cajal University Hospital-IRYCIS , Madrid ,","place":["Spain"]},{"name":"CIBERINFEC, Instituto de Salud Carlos III , Madrid ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3252-9748","authenticated-orcid":false,"given":"Marta","family":"Gonz\u00e1lez-Sanz","sequence":"additional","affiliation":[{"name":"National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ram\u00f3n y Cajal University Hospital-IRYCIS , Madrid ,","place":["Spain"]},{"name":"CIBERINFEC, Instituto de Salud Carlos III , Madrid ,","place":["Spain"]},{"name":"University of Alcal\u00e1 , Madrid ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5725-0102","authenticated-orcid":false,"given":"Sarah L","family":"McGuinness","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine, Monash University , Melbourne, VIC ,","place":["Australia"]},{"name":"Department of Infectious Diseases, Alfred Health , Melbourne, VIC ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5768-5109","authenticated-orcid":false,"given":"Andreas K","family":"Lindner","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2212 Universit\u00e4tsmedizin Berlin, Charit\u00e9 Center for Global Health, Institute of International Health , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Tedesco","sequence":"additional","affiliation":[{"name":"Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella , Verona ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Muriel","sequence":"additional","affiliation":[{"name":"University of Alcal\u00e1 , Madrid ,","place":["Spain"]},{"name":"Biostatistics Unit, Hospital Ram\u00f3n y Cajal, IRYCIS, CIBERESP , Madrid ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Gobbi","sequence":"additional","affiliation":[{"name":"Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella , Verona ,","place":["Italy"]},{"name":"Department of Clinical and Experimental Sciences, University of Brescia , Brescia ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3161-8199","authenticated-orcid":false,"given":"Stephen","family":"Muhi","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne , Melbourne, VIC ,","place":["Australia"]},{"name":"Victorian Infectious Diseases Service, Royal Melbourne Hospital , Parkville, VIC ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1368-1039","authenticated-orcid":false,"given":"Karin","family":"Leder","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine, Monash University , Melbourne, VIC ,","place":["Australia"]},{"name":"Victorian Infectious Diseases Service, Royal Melbourne Hospital , Parkville, VIC ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8735-4124","authenticated-orcid":false,"given":"Jose A","family":"P\u00e9rez Molina","sequence":"additional","affiliation":[{"name":"National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ram\u00f3n y Cajal University Hospital-IRYCIS , Madrid ,","place":["Spain"]},{"name":"CIBERINFEC, Instituto de Salud Carlos III , Madrid ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Rothe","sequence":"additional","affiliation":[{"name":"Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital , Munich ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Jordan","sequence":"additional","affiliation":[{"name":"Division of Tropical Medicine, I. 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