{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T04:09:01Z","timestamp":1779163741416,"version":"3.51.4"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2019,11,28]],"date-time":"2019-11-28T00:00:00Z","timestamp":1574899200000},"content-version":"vor","delay-in-days":331,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,23]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The incidence of sexually transmitted infections (STI) is increasing in Western countries whilst travel plays a major role in STI dissemination worldwide. However, there is no study distinguishing HIV-positive and HIV-negative travellers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively evaluated the epidemiological, clinical and biological characteristics of the patients diagnosed with a travel-related STI between 2008 and 2016. We describe and compare the spectrum of STI diagnosed amongst HIV-positive and negative travellers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Overall, 163 travel-related STI were identified in 140 patients (89% male, 54% men having sex with men, 40% HIV-positive). Symptoms occurred during travel in 39% of them, otherwise the median time between return and symptoms\u2019 onset was 13\u00a0days. Amongst the 84 HIV-negative travellers, the main STI were primary HIV infections (n\u2009=\u200936, 38%), Neisseria gonorrhoeae (NG) infections (17%) and primary herpes infection (14, vs 1.5% amongst HIV-positive travellers, P\u2009=\u20090.01). The regions of exposure to HIV were concordant with the known geographical distribution of HIV subtypes. Amongst the 56 HIV-positive travellers, the main STI were syphilis (43, vs 6% amongst HIV-negative travellers, P\u2009=\u20090.01), Chlamydia trachomatis (CT) infections (22, vs 13% amongst HIV-negative travellers, P\u2009=\u20090.08), NG infections (13%) and acute hepatitis C (12, vs 1% amongst HIV-negative travellers, P\u2009=\u20090.01), with a predominance of anal forms for both CT and NG infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The spectrum of STI diagnosed in returning travellers is broad with important differences according to HIV status. In our setting, primary HIV infection was the leading STI in non-HIV infected patients, which suggests that pre-exposure prophylaxis may have a role in HIV prevention in at-risk travellers.<\/jats:p><\/jats:sec>","DOI":"10.1093\/jtm\/taz090","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T20:09:59Z","timestamp":1574280599000},"source":"Crossref","is-referenced-by-count":11,"title":["Travel-associated STI amongst HIV and non-HIV infected travellers"],"prefix":"10.1093","volume":"26","author":[{"given":"Agathe","family":"Nouchi","sequence":"first","affiliation":[{"name":"Sorbonne Universit\u00e9, AP-HP, H\u00f4pitaux Universitaires Piti\u00e9-Salp\u00eatri\u00e8re Charles Foix, Service de Maladies Infectieuses et Tropicales, Department of Infectious and Tropical Diseases, Paris 75013, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabienne","family":"Caby","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Victor Dupouy Hospital, Argenteuil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romain","family":"Palich","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, AP-HP, H\u00f4pitaux Universitaires Piti\u00e9-Salp\u00eatri\u00e8re Charles Foix, Service de Maladies Infectieuses et Tropicales, Department of Infectious and Tropical Diseases, Paris 75013, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gentiane","family":"Monsel","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, AP-HP, H\u00f4pitaux Universitaires Piti\u00e9-Salp\u00eatri\u00e8re Charles Foix, Service de Maladies Infectieuses et Tropicales, Department of Infectious and Tropical Diseases, Paris 75013, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"and Eric","family":"Caumes","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, AP-HP, H\u00f4pitaux Universitaires Piti\u00e9-Salp\u00eatri\u00e8re Charles Foix, Service de Maladies Infectieuses et Tropicales, Department of Infectious and Tropical Diseases, Paris 75013, France"},{"name":"Sorbonne Universit\u00e9, INSERM, Pierre Louis Institute of Epidemiology and Public Health, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"key":"2019122309173270600_ref1","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1097\/01.olq.0000145846.45781.a4","article-title":"Fluoroquinolone resistance among Neisseria gonorrhoeae isolates in Hawaii, 1990\u20132000: role of foreign importation and increasing endemic spread","volume":"31","author":"Iverson","year":"2004","journal-title":"Sex Transm Dis"},{"key":"2019122309173270600_ref2","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2019.24.10.1900147","article-title":"Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018","volume":"24","author":"Eyre","year":"2019","journal-title":"Euro Surveill"},{"key":"2019122309173270600_ref3","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2017.22.20.30537","article-title":"Travel-associated gonorrhoea in four Nordic countries, 2008 to 2013","volume":"22","author":"Beaut\u00e9","year":"2017","journal-title":"Euro Surveill"},{"key":"2019122309173270600_ref4","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S1473-3099(03)00484-5","article-title":"Travel and the spread of HIV-1 genetic variants","volume":"3","author":"Perrin","year":"2003","journal-title":"Lancet Infect Dis"},{"key":"2019122309173270600_ref5","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1097\/00007435-200212000-00002","article-title":"Epidemics due to imported syphilis in Finland","volume":"29","author":"Hiltunen-Back","year":"2002","journal-title":"Sex Transm Dis"},{"key":"2019122309173270600_ref6","doi-asserted-by":"crossref","first-page":"3265","DOI":"10.1001\/jama.1987.03400220065038","article-title":"Chancroid in the United States. 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