{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T23:31:43Z","timestamp":1769038303268,"version":"3.49.0"},"reference-count":49,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Radiography is widely used to diagnose lower urinary tract (LUT) urolithiasis in cats. Non-invasive identification of urolith mineral composition (UMC) is critical for therapy selection but remains challenging, as most data derive from dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>To describe in vivo radiographic features of feline calcium oxalate and struvite LUT uroliths and identify distinguishing characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Sixty-nine cats with LUT uroliths containing \u226570% of calcium oxalate (n\u00a0=\u00a045) or struvite (n\u00a0=\u00a024).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective cross-sectional study. Radiographs were evaluated for urolith size, shape, surface, internal architecture, subjective radiopacity, and quantitative radiopacity, assessed using a ratio of urolith-to-L5 vertebra pixel values (UOR). Diagnostic performance of urolith size and UOR was assessed with receiver operating characteristic (ROC) curves, calculating the area under the ROC curve (AUC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Struvite uroliths had lower quantitative radiopacity with a UOR cut-off \u22640.78 (AUC\u00a0=\u00a00.81, P\u00a0&amp;lt;\u00a0.001; sensitivity: 58%, specificity: 92%). They were larger, with a cut-off value of \u22657.3\u00a0mm (AUC\u00a0=\u00a00.75, P\u00a0&amp;lt;\u00a0.001; sensitivity: 38%, specificity: 98%), more frequently irregularly shaped, with rough surface and heterogeneous architecture. Urease-positive bacteriuria was present in 43% of struvite uroliths; infected struvite uroliths were significantly larger (median, 9.8\u00a0mm; interquartile range [IQR], 5.4-13\u00a0mm) than sterile ones (median, 4.6\u00a0mm; IQR, 2.6-5.4\u00a0mm; P\u00a0=\u00a0.02). Calcium oxalate uroliths were frequently smaller, more radiopaque, uniform, smooth, and associated with nephroliths.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and clinical importance<\/jats:title>\n                    <jats:p>In vivo radiographic characteristics aid in differentiating struvite from calcium oxalate LUT uroliths, selecting non-invasive therapy, and reducing unnecessary surgeries.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jvimsj\/aalaf005","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T09:01:49Z","timestamp":1768986109000},"source":"Crossref","is-referenced-by-count":0,"title":["In vivo radiographic characteristics associated with the mineral composition of calcium oxalate and struvite lower urinary tract uroliths in cats"],"prefix":"10.1093","volume":"40","author":[{"given":"Diego","family":"Pulido Vega","sequence":"first","affiliation":[{"name":"Service of Diagnostic Imaging, \u00c9cole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort , Maisons-Alfort 94700 ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Dalmon","sequence":"additional","affiliation":[{"name":"\u00c9cole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort , Maisons-Alfort 94700 ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christelle","family":"Maurey","sequence":"additional","affiliation":[{"name":"Service of Internal Medicine, \u00c9cole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, INRAE, ANSES, UMR Virology, Laboratoire de Sant\u00e9 Animale , Maisons-Alfort 94700 ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Mortier","sequence":"additional","affiliation":[{"name":"Service of Diagnostic Imaging, \u00c9cole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort , 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