{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T11:37:16Z","timestamp":1770550636032,"version":"3.49.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":33,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Tufts Clinical and Translational Science Institute TL1 Training Program","award":["TL1TR002546"],"award-info":[{"award-number":["TL1TR002546"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Identifying factors associated with antimicrobial use in dogs and cats supports antimicrobial stewardship initiatives.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>Identify demographic, clinical, and treatment factors associated with prescribing systemic antimicrobial treatment in dogs and cats hospitalized at a small animal veterinary teaching hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Inpatient dogs (n\u00a0=\u00a09112) with 10\u2009749 admissions and inpatient cats (n\u00a0=\u00a03146) with 3684 admissions to a small animal teaching hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A veterinary-adapted Observational Medical Outcomes Partnership Common Data Model was used to analyze demographic, clinical, and prescription data from the electronic medical record system in this observational cross-sectional study. Using generalized estimating equations, we identified factors associated with systemic antimicrobial prescription during admission among inpatient dogs and cats from 2020 to 2022.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In dogs (mean age, 7.2\u00a0years; 47% females), factors associated with the highest odds of any antimicrobial prescription were history of surgery within the previous 10\u00a0days (odds ratio [OR], 2.4; 95% confidence interval [CI], 1.67-3.45), surgery during admission (OR, 2.11; 95% CI, 1.91-2.32), and venous sampling catheter placement (OR, 1.98; 95% CI, 1.58-2.49), adjusted for all covariables in the model. In cats (mean age, 8.4\u00a0years; 38% females), factors associated with the highest odds of any antimicrobial prescription were venous sampling catheter placement (OR, 3.25; 95% CI, 2.09-5.06), surgery during admission (OR, 1.58; 95% CI, 1.3-1.92), and admission duration (OR, 1.54; 95% CI, 1.44-1.65), adjusted for all covariables in the model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and clinical importance<\/jats:title>\n                    <jats:p>We identified multiple factors associated with antimicrobial use in inpatient dogs and cats that can support benchmark development and veterinary antimicrobial stewardship efforts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jvimsj\/aalaf070","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T16:45:15Z","timestamp":1770137115000},"source":"Crossref","is-referenced-by-count":0,"title":["Factors associated with antimicrobial drug prescription in inpatient dogs and cats at a veterinary teaching hospital"],"prefix":"10.1093","volume":"40","author":[{"given":"Emma R","family":"Price","sequence":"first","affiliation":[{"name":"Tufts Clinical and Translational Science Institute, Tufts University , Boston, MA 02111, \u00a0","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manlik","family":"Kwong","sequence":"additional","affiliation":[{"name":"Tufts Clinical and Translational Science Institute, Tufts University , Boston, MA 02111, \u00a0","place":["United States"]},{"name":"Institute for Clinical Research and Health Policy Studies, Tufts Medical Center , Boston, MA 02111 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie S","family":"Wayne","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University , North Grafton, MA 01536 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirthana R","family":"Beaulac","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Emerson Hospital , Concord, MA 01742 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian M","family":"DeStefano","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University , North Grafton, MA 01536 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Sebastiani","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University , North Grafton, MA 01536 ,","place":["United States"]},{"name":"School of Medicine, Tufts University , Boston, MA 02111 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shira I","family":"Doron","sequence":"additional","affiliation":[{"name":"Division of Geographic Medicine and Infectious Diseases, School of Medicine, Tufts Medical Center , Boston, MA 02116 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire L","family":"Fellman","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University , North Grafton, MA 01536 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"2026020706115914600_ref1","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1111\/zph.12167","article-title":"Reduction of veterinary antimicrobial use in the Netherlands. 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