{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:11:27Z","timestamp":1791483087153,"version":"4.3.4"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"vor","delay-in-days":46,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>A hypertrophic cardiomyopathy phenotype (HCMP) can occur in cats with hyperthyroidism. However, it remains unclear whether other cardiomyopathy phenotypes are also associated with hyperthyroidism in cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>Describe the epidemiological, clinical, and echocardiographic findings and cardiomyopathy phenotypes in a large sample of hyperthyroid cats. Compare the echocardiographic features of hyperthyroid cats with HCMP to those of a contemporaneous sample of normotensive euthyroid cats with primary hypertrophic cardiomyopathy (HCM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>A total of 147 hyperthyroid cats and 112 cats with primary HCM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective study with review of internal medicine and cardiology service databases (2005-2025).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most hyperthyroid cats (117\/147, 80%) exhibited 1 of the 3 cardiomyopathy phenotypes: HCMP (94\/147, 64%), restrictive cardiomyopathy phenotype (RCMP; 20\/147, 14%), or nonspecific (3\/147, 2%). Hyperthyroid cats with RCMP had significantly higher total thyroxine concentrations (median, 154\u00a0nmol\/L vs 95\u00a0nmol\/L) and more dyspnea related to congestive heart failure (80% vs 11%) than those with HCMP (P\u00a0&amp;lt;\u00a0.01). A gallop sound was detected in 10% of hyperthyroid cats (14\/147), exclusively in those with HCMP (10%, 9\/94) or RCMP (25%, 5\/20). The end-diastolic left ventricular diameter was higher in hyperthyroid cats with HCMP than in those with primary HCM (P\u00a0&amp;lt;\u00a0.01). Subaortic septal hypertrophy was more frequent (95% vs 67%) in cats with primary HCM than in those with hyperthyroidism-associated HCMP (P\u00a0&amp;lt;\u00a0.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and clinical importance<\/jats:title>\n                    <jats:p>The HCMP is the predominant, but not sole, echocardiographic phenotype observed in hyperthyroid cats. The RCMP is the second most frequent phenotype and may reflect a more severe form of hyperthyroidism.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jvimsj\/aalag006","type":"journal-article","created":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T17:11:02Z","timestamp":1771261862000},"source":"Crossref","is-referenced-by-count":1,"title":["Hypertrophic cardiomyopathy is not the sole echocardiographic phenotype associated with hyperthyroidism in cats: a retrospective study in 147 cats (2005-2025)"],"prefix":"10.1093","volume":"40","author":[{"given":"Pierre","family":"Foulex","sequence":"first","affiliation":[{"name":"Veranex France , Paris ,","place":["France"]},{"name":"Clinique v\u00e9t\u00e9rinaire Boulogne Roland-Garros , Boulogne-Billancourt ,","place":["France"]},{"name":"Sudvetia , Aix-en-Provence 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