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Magnetic resonance imaging (MRI) identified an intramedullary mass that was T2 hyperintense, T1 iso- to hypointense, short tau inversion recovery (STIR) hyperintense, strongly rim-enhancing, and centrally suppressed on post-contrast T2-fluid-attenuated inversion recovery (FLAIR) images. Despite a suspected glial cell neoplasm, clinical signs initially improved with palliative treatment. Follow-up MRI 2 years later showed progressive enlargement of the lesion, with newly noted multiseptated regions. Histopathology indicated a high-grade oligodendroglioma.<\/jats:p>","DOI":"10.1093\/jvimsj\/aalag151","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T19:35:40Z","timestamp":1784835340000},"source":"Crossref","is-referenced-by-count":0,"title":["Unusually slow progression of a high-grade intramedullary oligodendroglioma in a dog: serial magnetic resonance imaging findings and clinical course over two years"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8678-8962","authenticated-orcid":false,"given":"Robert","family":"Wise","sequence":"first","affiliation":[{"name":"Section of Radiology, Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania, School of Veterinary Medicine , Philadelphia, PA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6431-3434","authenticated-orcid":false,"given":"Lillian 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