{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:56:17Z","timestamp":1790780177600,"version":"4.1.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"VES Hospital and Singapore Veterinary Health"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The clinical manifestations and outcomes in dogs and cats with melioidosis have not been described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>Describe the presenting signs, treatment, and outcome of dogs and cats with melioidosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Fifteen dogs and 3 cats from a hospital in Singapore.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective case series. A hospital database search was performed to identify dogs with melioidosis presenting over a 5-year period. Data collected included signalment, clinical signs, test results, treatment, and outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Diagnosis was based on positive bacterial culture and identification of Burkholderia pseudomallei in all cases. At presentation, 13\/15 (87%) had systemic inflammatory response syndrome (SIRS), 10\/15 (67%) were septic, and 3\/15 (20%) had septic shock. In dogs, 8\/15 (53%) had multiple cutaneous abscesses or open wounds, and 6\/15 (40%) had prostatitis or prostatic abscessation. In cats, 2\/3 had osteomyelitis and 1\/3 had pyelonephritis. Of the cases, 5\/15 (33%) dogs and none of the cats were considered potentially immunocompromised. Of the 17 cases with &amp;gt;4\u00a0weeks of follow-up, death or euthanasia attributed to melioidosis occurred in 8\/17 (47%). Of the surviving 9\/17 (53%) animals, 6 were alive after 1 month (range, 1-43\u00a0months) and 3 died or were euthanized for reasons unrelated to melioidosis, with median follow-up duration of 724\u00a0days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and clinical importance<\/jats:title>\n                    <jats:p>Melioidosis should be considered in dogs with prostatitis or cutaneous abscesses, and in cats with osteomyelitis. Initial treatment with ceftazidime or meropenem, followed by 3-6\u00a0months of trimethoprim-sulfonamide (TMPS) might be optimal.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jvimsj\/aalag221","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:09:06Z","timestamp":1790777346000},"source":"Crossref","is-referenced-by-count":0,"title":["Melioidosis in dogs and cats: 18 cases"],"prefix":"10.1093","volume":"40","author":[{"given":"Ziyue Sharon","family":"Lim","sequence":"first","affiliation":[{"name":"Internal Medicine Department, VES Hospital , 232 Whitley Road, 297824 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent","family":"Soon","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, VES Hospital , 232 Whitley Road, 297824 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Neo","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, VES Hospital , 232 Whitley Road, 297824 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Labrador","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging Department, VES Hospital , 232 Whitley Road, 297824 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren","family":"Kelly","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, VES Hospital , 232 Whitley Road, 297824 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"2026093010090297900_ref1","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3390\/tropicalmed3010031","article-title":"Melioidosis 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