{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:52:27Z","timestamp":1791039147632,"version":"4.1.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:00:00Z","timestamp":1790985600000},"content-version":"vor","delay-in-days":32,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Phaeohyphomycosis is an opportunistic mycosis caused by dematiaceous fungi, typically affecting the cutaneous or subcutaneous tissues of the facial region and distal extremities in cats. This report documents a case of Cladophialophora boppii infection in a cat. A 7-year-old neutered male domestic shorthair cat was presented with a chronic, pigmented nasal lesion, non-productive sneezing, and stertor. Computed tomography, rhinoscopy, and tissue sampling were performed. Fungal culture and molecular sequencing confirmed the diagnosis. Oral itraconazole treatment failed to arrest progression, necessitating delayed nasal planectomy. Despite transient remission, disease recurred, requiring repeat surgical debridement, and prolonged antifungal treatment. Clinical resolution was ultimately achieved, with marked improvement in the cat\u2019s quality of life. Identification of a novel species of phaeohyphomycosis in a cat emphasizes the need for increased awareness of emerging fungal pathogens that can precipitate considerable morbidity, particularly in the absence of prompt aggressive intervention.<\/jats:p>","DOI":"10.1093\/jvimsj\/aalag235","type":"journal-article","created":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T13:52:40Z","timestamp":1791035560000},"source":"Crossref","is-referenced-by-count":0,"title":["Nasal phaeohyphomycosis in a cat caused by\n                    <i>Cladophialophora boppii<\/i>"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1362-2063","authenticated-orcid":false,"given":"Julia","family":"McCarthy","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine, University College Dublin , Dublin D04 W6F6 ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9482-3619","authenticated-orcid":false,"given":"Monica","family":"Augusto","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, University College Dublin , Dublin D04 W6F6 ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5882-7797","authenticated-orcid":false,"given":"Emma","family":"O'Neill","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, University College Dublin , Dublin D04 W6F6 ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3091-1393","authenticated-orcid":false,"given":"Ignacio","family":"Otero Balda","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, University College Dublin , Dublin D04 W6F6 ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0757-6788","authenticated-orcid":false,"given":"Eleanor","family":"Wyatt","sequence":"additional","affiliation":[{"name":"Northwest Veterinary Specialists, Part of Linnaeus Ltd , Runcorn WA7 3FW ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,3]]},"reference":[{"key":"2026100309523516500_ref1","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1016\/B978-0-323-50934-3.00087-2","volume-title":"Greene's Infectious Diseases of the Dog and Cat","author":"Grooters","year":"2021","edition":"5"},{"key":"2026100309523516500_ref2","doi-asserted-by":"publisher","first-page":"1098612X231219696","DOI":"10.1177\/1098612X231219696","article-title":"Invasive fungal infections and oomycoses in cats: 1. Diagnostic approach","volume":"26","author":"Barrs","year":"2024","journal-title":"J Feline Med Surg"},{"key":"2026100309523516500_ref3","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1093\/mmy\/myv018","article-title":"Phaeohyphomycosis in transplant recipients: results from the transplant associated infection surveillance network (TRANSNET)","volume":"53","author":"McCarty","year":"2015","journal-title":"Med Mycol"},{"key":"2026100309523516500_ref4","doi-asserted-by":"publisher","first-page":"100156","DOI":"10.1016\/j.joclim.2022.100156","article-title":"The effects of climate change on fungal diseases with cutaneous manifestations: a report from the International Society of Dermatology Climate Change Committee","volume":"6","author":"Gadre","year":"2022","journal-title":"J Clim Change Health"},{"key":"2026100309523516500_ref5","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1086\/597400","article-title":"Phaeohyphomycosis in a tertiary care cancer center","volume":"48","author":"Ben-Ami","year":"2009","journal-title":"Clin Infect Dis"},{"key":"2026100309523516500_ref6","doi-asserted-by":"publisher","first-page":"895329","DOI":"10.3389\/fcimb.2022.895329","article-title":"Phaeohyphomycosis in China","volume":"12","author":"He","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"2026100309523516500_ref7","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1080\/21505594.2019.1596504","article-title":"Exophiala dermatitidis: key issues of an opportunistic fungal pathogen","volume":"10","author":"Kirchhoff","year":"2019","journal-title":"Virulence"},{"key":"2026100309523516500_ref8","doi-asserted-by":"publisher","first-page":"695","DOI":"10.4103\/0378-6323.72474","article-title":"Subcutaneous phaeohyphomycosis caused by Cladophialophora boppii","volume":"76","author":"Pereira","year":"2010","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"2026100309523516500_ref9","doi-asserted-by":"publisher","first-page":"190","DOI":"10.3109\/13693786.2010.516458","article-title":"Toenail infection by Cladophialophora boppii","volume":"49","author":"Brasch","year":"2011","journal-title":"Med Mycol"},{"key":"2026100309523516500_ref10","doi-asserted-by":"publisher","first-page":"102006","DOI":"10.1016\/j.ajoc.2024.102006","article-title":"Dematiaceous fungal keratitis caused by Cladophialophora boppii - a case report","volume":"33","author":"Fukuoka","year":"2024","journal-title":"Am J Ophthalmol Case Rep"},{"key":"2026100309523516500_ref11","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/j.healun.2009.02.014","article-title":"Pulmonary Cladophialophora boppii infection in a lung transplant recipient: case report and literature review","volume":"28","author":"Lastoria","year":"2009","journal-title":"J Heart Lung Transplant"},{"key":"2026100309523516500_ref12","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1111\/avj.13436","article-title":"Myelopathy caused by Cladophialophora bantiana in a dog and a cat","volume":"103","author":"McLeay","year":"2025","journal-title":"Aust Vet J"},{"key":"2026100309523516500_ref13","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1177\/1098612X14559954","article-title":"South African report of first case of chromoblastomycosis caused by Cladosporium (syn Cladophialophora) carrionii infection in a cat with feline immunodeficiency virus and lymphosarcoma","volume":"17","author":"Zambelli","year":"2015","journal-title":"J Feline Med Surg"},{"key":"2026100309523516500_ref14","doi-asserted-by":"publisher","first-page":"e62","DOI":"10.1055\/s-0037-1598248","article-title":"Cladophialophora bantiana: a rare intracerebral fungal abscess-case series and review of literature","volume":"03","author":"Ahmad","year":"2017","journal-title":"Surg J (N Y)"},{"key":"2026100309523516500_ref15","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1053\/jfms.2002.0183","article-title":"Feline cutaneous phaeohyphomycosis due to Cladophyalophora bantiana","volume":"4","author":"Abramo","year":"2002","journal-title":"J Feline Med Surg"},{"key":"2026100309523516500_ref16","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1046\/j.1439-0442.2003.00501.x","article-title":"Fatal systemic phaeohyphomycosis in a cat due to Cladophialophora bantiana","volume":"50","author":"Elies","year":"2003","journal-title":"J Vet Med A Physiol Pathol Clin Med"},{"key":"2026100309523516500_ref17","doi-asserted-by":"publisher","first-page":"194","DOI":"10.3109\/13693786.2010.519349","article-title":"Focal pulmonary granuloma caused by Cladophialophora bantiana in a domestic short haired cat","volume":"49","author":"Evans","year":"2011","journal-title":"Med Mycol"},{"key":"2026100309523516500_ref18","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1136\/vr.161.21.724","article-title":"Fungal pyelonephritis due to Cladophialophora bantiana in a cat","volume":"161","author":"Coldrick","year":"2007","journal-title":"Veterinary Record"},{"key":"2026100309523516500_ref19","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1111\/myc.12033","article-title":"Canine eumycetoma caused by Cladophialophora bantiana in a maltese: case report and literature review","volume":"56","author":"Sun","year":"2013","journal-title":"Mycoses"},{"key":"2026100309523516500_ref20","doi-asserted-by":"publisher","first-page":"50","DOI":"10.22456\/1679-9216.119283","article-title":"Systemic phaeohyphomycosis in a dog caused by Cladophialophora bantiana","volume":"50","author":"Alves","year":"2022","journal-title":"Acta Scientiae Veterinariae"},{"key":"2026100309523516500_ref21","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/B978-0-12-372180-8.50042-1","volume-title":"Amplification and direct sequencing of fungal ribosomal RNA Genes for phylogenetics","author":"White","year":"1990"},{"key":"2026100309523516500_ref22","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1128\/aem.61.4.1323-1330.1995","article-title":"Development of primer sets designed for use with the PCR to amplify conserved genes from filamentous ascomycetes","volume":"61","author":"Glass","year":"1995","journal-title":"Appl Environ Microbiol"},{"key":"2026100309523516500_ref23","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1128\/JCM.42.1.404-407.2004","article-title":"Specific oligonucleotide primers for identification of Cladophialophora carrionii, a causative agent of chromoblastomycosis","volume":"42","author":"Abliz","year":"2004","journal-title":"J Clin Microbiol"},{"key":"2026100309523516500_ref24","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.cvsm.2013.08.001","article-title":"Feline aspergillosis","volume":"44","author":"Barrs","year":"2014","journal-title":"Vet Clin N Am Small Anim Pract"},{"key":"2026100309523516500_ref25","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1111\/jsap.13265","article-title":"Melanocytic tumours of the nasal planum in cats: 10 cases (2004-2019)","volume":"62","author":"Reck","year":"2021","journal-title":"J Small Anim Pract"},{"key":"2026100309523516500_ref26","doi-asserted-by":"publisher","first-page":"1098612X231220047","DOI":"10.1177\/1098612X231220047","article-title":"Invasive fungal infections and oomycoses in cats 2. Antifungal therapy","volume":"26","author":"Barrs","year":"2024","journal-title":"J Feline Med Surg"},{"key":"2026100309523516500_ref27","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1177\/1098612X15581408","article-title":"Pharmacokinetics and bioavailability of itraconazole oral solution in cats","volume":"18","author":"Liang","year":"2016","journal-title":"J Feline Med Surg"},{"key":"2026100309523516500_ref28","doi-asserted-by":"publisher","first-page":"e250","DOI":"10.1111\/1346-8138.15357","article-title":"Case of phaeohyphomycosis caused by Cladophialophora boppii successfully treated with local hyperthermia and systemic terbinafine","volume":"47","author":"Saito","year":"2020","journal-title":"J Dermatol"},{"key":"2026100309523516500_ref29","doi-asserted-by":"publisher","first-page":"100717","DOI":"10.1016\/j.mmcr.2025.100717","article-title":"Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: a case report","volume":"49","author":"Cavens","year":"2025","journal-title":"Med Mycol Case Rep"}],"container-title":["Journal of Veterinary Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/40\/5\/aalag235\/71576615\/aalag235.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/40\/5\/aalag235\/71576615\/aalag235.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T13:52:41Z","timestamp":1791035561000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jvim\/article\/doi\/10.1093\/jvimsj\/aalag235\/8860265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,1]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jvimsj\/aalag235","relation":{},"ISSN":["1939-1676"],"issn-type":[{"value":"1939-1676","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,9,1]]},"article-number":"aalag235"}}