{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T16:42:21Z","timestamp":1792773741211,"version":"4.5.0"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"vor","delay-in-days":52,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Platelet transfusion can be lifesaving in dogs with severe thrombocytopenia and hemorrhage, but platelet products are limited by short shelf life and contamination risk. Cold-stored platelets (CSP) may provide a practical alternative, but in vivo hemostatic efficacy in dogs is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>Evaluate the clinical hemostatic efficacy and safety of CSP transfusions in thrombocytopenic dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Twenty-four thrombocytopenic dogs from a veterinary teaching hospital population that received CSP transfusions between March 2022 and October 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective cohort study. Medical records of dogs receiving platelet concentrate stored at 4\u00a0\u00b0C for up to 21\u00a0days were reviewed. Hemorrhage severity was assessed using a modified Daily Canine Bleeding Assessment Tool (DOGiBAT) score before transfusion and at 1 and 4\u00a0h post-transfusion. Primary outcomes included change in bleeding score, clinical response, transfusion reactions, and survival to discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-four dogs received 27 CSP transfusions. Mean pre-transfusion platelet count was 23\u00a0\u00d7\u00a0103\/\u03bcL (range, 2-107\u00a0\u00d7\u00a0103\/\u03bcL) and mean post-transfusion count was 28\u00a0\u00d7\u00a0103\/\u03bcL (range, 2-100\u00a0\u00d7\u00a0103\/\u03bcL; P\u00a0=\u00a0.84). Mean DOGiBAT score decreased from 3.15\u00a0\u00b1\u00a02.4 at baseline to 2.21\u00a0\u00b1\u00a02.1 at 4\u00a0(mean change, \u22120.94; P\u00a0=\u00a0.002). Clinical improvement occurred in 19 of 27 transfusions (70%). No transfusion reactions were documented. Nineteen of 24 dogs (79%) survived to discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and clinical importance<\/jats:title>\n                    <jats:p>Cold-stored platelets were well-tolerated and associated with decreased bleeding severity in thrombocytopenic dogs, supporting CSP as a practical platelet transfusion option for clinical hemostatic support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jvimsj\/aalag262","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T16:05:05Z","timestamp":1792771505000},"source":"Crossref","is-referenced-by-count":0,"title":["The use of cold-stored platelets to provide hemostasis in dogs with thrombocytopenia"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5285-6953","authenticated-orcid":false,"given":"Shannon A","family":"Monaco","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Washington State University College of Veterinary Medicine , Pullman, WA 99163 \u00a0","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8066-838X","authenticated-orcid":false,"given":"Jillian M","family":"Haines","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Washington State University College of Veterinary Medicine , Pullman, WA 99163 \u00a0","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1472-343X","authenticated-orcid":false,"given":"Sarah C","family":"Guess","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Washington State University College of Veterinary Medicine , Pullman, WA 99163 \u00a0","place":["United 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