{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T11:11:43Z","timestamp":1790766703684,"version":"4.1.0"},"reference-count":74,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T00:00:00Z","timestamp":1699660800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011033","name":"Agencia Estatal de Investigaci\u00f3n","doi-asserted-by":"publisher","award":["AGL2017-85775-R"],"award-info":[{"award-number":["AGL2017-85775-R"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"Agencia Estatal de Investigaci\u00f3n","doi-asserted-by":"publisher","award":["PID2020-113985GB-I00"],"award-info":[{"award-number":["PID2020-113985GB-I00"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"Agencia Estatal de Investigaci\u00f3n","doi-asserted-by":"publisher","award":["A09_20R"],"award-info":[{"award-number":["A09_20R"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"Agencia Estatal de Investigaci\u00f3n","doi-asserted-by":"publisher","award":["A09_23R"],"award-info":[{"award-number":["A09_23R"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Unit of Information Resources for Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Legumes establish symbiosis with rhizobia, forming nitrogen-fixing nodules. The central role of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in nodule biology has been clearly established. Recently, hydrogen sulfide (H2S) and other reactive sulfur species (RSS) have emerged as novel signaling molecules in animals and plants. A major mechanism by which ROS, RNS, and RSS fulfil their signaling role is the post-translational modification of proteins. To identify possible functions of H2S in nodule development and senescence, we used the tag-switch method to quantify changes in the persulfidation profile of common bean (Phaseolus vulgaris) nodules at different developmental stages. Proteomic analyses indicate that persulfidation plays a regulatory role in plant and bacteroid metabolism and senescence. The effect of a H2S donor on nodule functioning and on several proteins involved in ROS and RNS homeostasis was also investigated. Our results using recombinant proteins and nodulated plants support a crosstalk among H2S, ROS, and RNS, a protective function of persulfidation on redox-sensitive enzymes, and a beneficial effect of H2S on symbiotic nitrogen fixation. We conclude that the general decrease of persulfidation levels observed in plant proteins of aging nodules is one of the mechanisms that disrupt redox homeostasis leading to senescence.<\/jats:p>","DOI":"10.1093\/jxb\/erad436","type":"journal-article","created":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T13:08:31Z","timestamp":1699794511000},"page":"3009-3025","source":"Crossref","is-referenced-by-count":21,"title":["Persulfidation of plant and bacteroid proteins is involved in legume nodule development and senescence"],"prefix":"10.1093","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5050-8062","authenticated-orcid":false,"given":"Manuel A","family":"Matamoros","sequence":"first","affiliation":[{"name":"Departamento de Biolog\u00eda Vegetal, Estaci\u00f3n Experimental de Aula Dei, Consejo Superior de Investigaciones Cient\u00edficas , Avenida Monta\u00f1ana 1005, 50059 Zaragoza , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2414-4813","authenticated-orcid":false,"given":"Luis C","family":"Romero","sequence":"additional","affiliation":[{"name":"Instituto de Bioqu\u00edmica Vegetal y Fotos\u00edntesis, Consejo Superior de Investigaciones Cient\u00edficas y Universidad de Sevilla , 41092 Sevilla , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Tian","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University , Wuhan 430070 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngela","family":"Rom\u00e1n","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda Vegetal, Estaci\u00f3n Experimental de Aula Dei, Consejo Superior de Investigaciones Cient\u00edficas , Avenida Monta\u00f1ana 1005, 50059 Zaragoza , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9365-362X","authenticated-orcid":false,"given":"Deqiang","family":"Duanmu","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University , Wuhan 430070 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1083-0804","authenticated-orcid":false,"given":"Manuel","family":"Becana","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda Vegetal, Estaci\u00f3n Experimental de Aula Dei, Consejo Superior de Investigaciones Cient\u00edficas , Avenida Monta\u00f1ana 1005, 50059 Zaragoza , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,11]]},"reference":[{"key":"2024052005521323900_CIT0001","doi-asserted-by":"crossref","first-page":"4915","DOI":"10.1093\/jxb\/erx294","article-title":"Persulfidation proteome reveals the regulation of protein function by hydrogen sulfide in diverse biological processes in Arabidopsis","volume":"68","author":"Aroca","year":"2017","journal-title":"Journal of Experimental Botany"},{"key":"2024052005521323900_CIT0002","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.3389\/fpls.2018.01369","article-title":"Hydrogen sulfide signaling in plants: emerging roles of protein persulfidation","volume":"9","author":"Aroca","year":"2018","journal-title":"Frontiers in Plant Science"},{"key":"2024052005521323900_CIT0003","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1104\/pp.15.00009","article-title":"S-sulfhydration: a cysteine posttranslational modification in plant systems","volume":"168","author":"Aroca","year":"2015","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0004","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0076-6879(84)05059-X","article-title":"Chloroplasts: formation of active oxygen and its scavenging","volume":"105","author":"Asada","year":"1984","journal-title":"Methods in Enzymology"},{"key":"2024052005521323900_CIT0005","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.redox.2017.09.009","article-title":"Fundamentals on the biochemistry of peroxynitrite and protein tyrosine nitration","volume":"14","author":"Bartesaghi","year":"2018","journal-title":"Redox Biology"},{"key":"2024052005521323900_CIT0006","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1104\/pp.123.1.335","article-title":"Ascorbate biosynthesis in mitochondria is linked to the electron transport chain between complexes III and IV","volume":"123","author":"Bartoli","year":"2000","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0007","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1034\/j.1399-3054.2000.100402.x","article-title":"Reactive oxygen species and antioxidants in legume nodules","volume":"109","author":"Becana","year":"2000","journal-title":"Physiologia Plantarum"},{"key":"2024052005521323900_CIT0008","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1111\/j.1469-8137.2010.03512.x","article-title":"Recent insights into antioxidant defenses of legume root nodules","volume":"188","author":"Becana","year":"2010","journal-title":"New Phytologist"},{"key":"2024052005521323900_CIT0009","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.3389\/fpls.2018.01434","article-title":"Sulfur transport and metabolism in legume root nodules","volume":"9","author":"Becana","year":"2018","journal-title":"Frontiers in Plant Science"},{"key":"2024052005521323900_CIT0010","doi-asserted-by":"crossref","first-page":"42494","DOI":"10.1038\/srep42494","article-title":"Arabidopsis thaliana dehydroascorbate reductase 2: Conformational flexibility during catalysis","volume":"7","author":"Bodra","year":"2017","journal-title":"Scientific Reports"},{"key":"2024052005521323900_CIT0011","doi-asserted-by":"crossref","first-page":"4419","DOI":"10.1093\/jxb\/erz117","article-title":"Nitric oxide in plants: pro- or anti-senescence","volume":"70","author":"Bruand","year":"2019","journal-title":"Journal of Experimental Botany"},{"key":"2024052005521323900_CIT0012","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/s41477-021-00887-0","article-title":"Stress-induced reactive oxygen species compartmentalization, perception and signalling","volume":"7","author":"Castro","year":"2021","journal-title":"Nature Plants"},{"key":"2024052005521323900_CIT0013","first-page":"117","article-title":"Inactivation of ascorbate peroxidase by thiols requires hydrogen peroxide","volume":"33","author":"Chen","year":"1992","journal-title":"Plant and Cell Physiology"},{"key":"2024052005521323900_CIT0014","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.molp.2020.01.004","article-title":"Hydrogen sulfide positively regulates abscisic acid signaling through persulfidation of SnRK26 in guard cells","volume":"13","author":"Chen","year":"2020","journal-title":"Molecular Plant"},{"key":"2024052005521323900_CIT0015","doi-asserted-by":"crossref","first-page":"2862","DOI":"10.1093\/jxb\/eraa093","article-title":"Hydrogen sulfide: a multi-tasking signal molecule in the regulation of oxidative stress responses","volume":"71","author":"Chen","year":"2020","journal-title":"Journal of Experimental Botany"},{"key":"2024052005521323900_CIT0016","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3389\/fpls.2013.00029","article-title":"Protein tyrosine nitration in higher plants grown under natural and stress conditions","volume":"4","author":"Corpas","year":"2013","journal-title":"Frontiers in Plant Science"},{"key":"2024052005521323900_CIT0017","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1104\/pp.83.4.789","article-title":"Purification, properties, and distribution of ascorbate peroxidase in legume root nodules","volume":"83","author":"Dalton","year":"1987","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0018","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0003-9861(92)90080-G","article-title":"Purification and characterization of monodehydroascorbate reductase from soybean root nodules","volume":"292","author":"Dalton","year":"1992","journal-title":"Archives of Biochemistry and Biophysics"},{"key":"2024052005521323900_CIT0019","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1093\/jxb\/erj160","article-title":"The function of peroxiredoxins in plant organelle redox metabolism","volume":"57","author":"Dietz","year":"2006","journal-title":"Journal of Experimental Botany"},{"key":"2024052005521323900_CIT0020","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1021\/acs.chemrev.7b00205","article-title":"Chemical biology of H2S signaling through persulfidation","volume":"118","author":"Filipovic","year":"2018","journal-title":"Chemical Reviews"},{"key":"2024052005521323900_CIT0021","first-page":"1469","article-title":"Posttranslational protein modifications in plant metabolism","volume":"169","author":"Friso","year":"2015","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0022","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3390\/antiox9020145","article-title":"Reactive sulfur species interact with other signal molecules in root nodule symbiosis in Lotus japonicus","volume":"9","author":"Fukudome","year":"2020","journal-title":"Antioxidants"},{"key":"2024052005521323900_CIT0023","doi-asserted-by":"crossref","first-page":"D261","DOI":"10.1093\/nar\/gku1223","article-title":"Expanded microbial genome coverage and improved protein family annotation in the COG database","volume":"43","author":"Galperin","year":"2015","journal-title":"Nucleic Acids Research"},{"key":"2024052005521323900_CIT0024","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1104\/pp.18.01083","article-title":"HCN regulates cellular processes through posttranslational modification of proteins by S-cyanylation","volume":"179","author":"Garc\u00eda","year":"2019","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0025","doi-asserted-by":"crossref","first-page":"4251","DOI":"10.1093\/jxb\/erz225","article-title":"Signaling by hydrogen sulfide and cyanide through post-translational modification","volume":"70","author":"Gotor","year":"2019","journal-title":"Journal of Experimental Botany"},{"key":"2024052005521323900_CIT0026","doi-asserted-by":"crossref","first-page":"3843","DOI":"10.1016\/j.febslet.2011.10.036","article-title":"Plant hemoglobins: Important players at the crossroads between oxygen and nitric oxide","volume":"585","author":"Gupta","year":"2011","journal-title":"FEBS Letters"},{"key":"2024052005521323900_CIT0027","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.molp.2021.12.012","article-title":"Nitric oxide regulation of plant metabolism","volume":"15","author":"Gupta","year":"2022","journal-title":"Molecular Plant"},{"key":"2024052005521323900_CIT0028","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.envexpbot.2018.08.034","article-title":"Hydrogen sulfide and environmental stresses","volume":"161","author":"Hancock","year":"2019","journal-title":"Environmental and Experimental Botany"},{"key":"2024052005521323900_CIT0029","doi-asserted-by":"crossref","first-page":"D1064","DOI":"10.1093\/nar\/gkw1041","article-title":"SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations","volume":"45","author":"Hooper","year":"2017","journal-title":"Nucleic Acids Research"},{"key":"2024052005521323900_CIT0030","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1104\/pp.15.00026","article-title":"Site-specific nitrosoproteomic identification of endogenously S-nitrosylated proteins in Arabidopsis","volume":"167","author":"Hu","year":"2015","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0031","doi-asserted-by":"crossref","first-page":"21256","DOI":"10.1073\/pnas.1906768116","article-title":"Mining for protein S-sulfenylation in Arabidopsis uncovers redox-sensitive sites","volume":"116","author":"Huang","year":"2019","journal-title":"Proceedings of the National Academy of Sciences, USA"},{"key":"2024052005521323900_CIT0032","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1094\/MPMI.2001.14.10.1189","article-title":"The antioxidants of legume nodule mitochondria","volume":"14","author":"Iturbe-Ormaetxe","year":"2001","journal-title":"Molecular Plant-Microbe Interactions"},{"key":"2024052005521323900_CIT0033","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jinorgbio.2018.02.007","article-title":"Reactions of ferric hemoglobin and myoglobin with hydrogen sulfide under physiological conditions","volume":"182","author":"Jensen","year":"2018","journal-title":"Journal of Inorganic Biochemistry"},{"key":"2024052005521323900_CIT0034","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/pro.4172","article-title":"KEGG mapping tools for uncovering hidden features in biological data","volume":"31","author":"Kanehisa","year":"2022","journal-title":"Protein Science"},{"key":"2024052005521323900_CIT0035","doi-asserted-by":"crossref","first-page":"678111","DOI":"10.3389\/fpls.2021.678111","article-title":"Regulation of dual activity of ascorbate peroxidase 1 from Arabidopsis thaliana by conformational changes and posttranslational modifications","volume":"12","author":"Kaur","year":"2021","journal-title":"Frontiers in Plant Science"},{"key":"2024052005521323900_CIT0036","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.plaphy.2017.01.028","article-title":"Protein tyrosine nitration in plants: Present knowledge, computational prediction and future perspectives","volume":"113","author":"Kolbert","year":"2017","journal-title":"Plant Physiology and Biochemistry"},{"key":"2024052005521323900_CIT0037","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/nph.16673","article-title":"Hemoglobins in the legume\u2013Rhizobium symbiosis","volume":"228","author":"Larrainzar","year":"2020","journal-title":"New Phytologist"},{"key":"2024052005521323900_CIT0038","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1104\/pp.109.136929","article-title":"Galactonolactone dehydrogenase requires a redox-sensitive thiol for optimal production of vitamin C","volume":"150","author":"Leferink","year":"2009","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0039","doi-asserted-by":"crossref","first-page":"3249","DOI":"10.1111\/pce.14431","article-title":"Interactions between hydrogen sulphide and rhizobia modulate the physiological and metabolism process during water deficiency-induced oxidative defense in soybean","volume":"45","author":"Lin","year":"2022","journal-title":"Plant, Cell & Environment"},{"key":"2024052005521323900_CIT0040","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.freeradbiomed.2017.11.027","article-title":"Crosstalk between reactive oxygen species and nitric oxide in plants: Key role of S-nitrosoglutathione reductase","volume":"122","author":"Lindermayr","year":"2018","journal-title":"Free Radical Biology and Medicine"},{"key":"2024052005521323900_CIT0041","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1104\/pp.107.114066","article-title":"Ascorbate and homoglutathione metabolism in common bean nodules under stress conditions and during natural senescence","volume":"146","author":"Loscos","year":"2008","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0042","first-page":"67","article-title":"Redox control of the legume-Rhizobium symbiosis","volume-title":"Advances in Botanical Research","author":"Matamoros","year":"2020"},{"key":"2024052005521323900_CIT0043","doi-asserted-by":"crossref","first-page":"5876","DOI":"10.1093\/jxb\/erab008","article-title":"Molecular responses of legumes to abiotic stress: posttranslational modifications of proteins and redox signaling","volume":"72","author":"Matamoros","year":"2021","journal-title":"Journal of Experimental Botany"},{"key":"2024052005521323900_CIT0044","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1111\/nph.12049","article-title":"Mitochondria are an early target of oxidative modifications in senescing legume nodules","volume":"197","author":"Matamoros","year":"2013","journal-title":"New Phytologist"},{"key":"2024052005521323900_CIT0045","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1093\/jxb\/erv066","article-title":"Function of glutathione peroxidases in legume root nodules","volume":"66","author":"Matamoros","year":"2015","journal-title":"Journal of Experimental Botany"},{"key":"2024052005521323900_CIT0046","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1111\/nph.18434","article-title":"Signaling by reactive molecules and antioxidants in legume nodules","volume":"236","author":"Minguill\u00f3n","year":"2022","journal-title":"New Phytologist"},{"key":"2024052005521323900_CIT0047","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nchembio.1834","article-title":"Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways","volume":"11","author":"Mishanina","year":"2015","journal-title":"Nature Chemical Biology"},{"key":"2024052005521323900_CIT0048","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1104\/pp.103.023010","article-title":"Functional characterization and expression of a cytosolic iron-superoxide dismutase from cowpea root nodules","volume":"133","author":"Moran","year":"2003","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0049","first-page":"867","article-title":"Hydrogen peroxide is scavenged by ascorbate specific peroxidase is spinach chloroplasts","volume":"22","author":"Nakano","year":"1981","journal-title":"Plant and Cell Physiology"},{"key":"2024052005521323900_CIT0050","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1104\/pp.106.089458","article-title":"Plant glutathione peroxidases are functional peroxiredoxins distributed in several subcellular compartments and regulated during biotic and abiotic stresses","volume":"142","author":"Navrot","year":"2006","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0051","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1104\/pp.16.00346","article-title":"Intracellular redox compartmentation and ROS-related communication in regulation and signaling","volume":"171","author":"Noctor","year":"2016","journal-title":"Plant Physiology"},{"key":"2024052005521323900_CIT0052","doi-asserted-by":"crossref","first-page":"4102","DOI":"10.1016\/j.jprot.2012.05.024","article-title":"Sulfenylated proteins in the Medicago truncatula-Sinorhizobium meliloti symbiosis","volume":"75","author":"Oger","year":"2012","journal-title":"Journal of Proteomics"},{"key":"2024052005521323900_CIT0053","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1186\/1471-2164-15-866","article-title":"An RNA-Seq based gene expression atlas of the common bean","volume":"15","author":"O\u2019Rourke","year":"2014","journal-title":"BMC Genomics"},{"key":"2024052005521323900_CIT0054","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.plantsci.2015.01.017","article-title":"Glutathione peroxidases as redox sensor proteins in plant cells","volume":"234","author":"Passaia","year":"2015","journal-title":"Plant Science"},{"key":"2024052005521323900_CIT0055","doi-asserted-by":"crossref","first-page":"D543","DOI":"10.1093\/nar\/gkab1038","article-title":"The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences","volume":"50","author":"Perez-Riverol","year":"2022","journal-title":"Nucleic Acids Research"},{"key":"2024052005521323900_CIT0056","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/j.1469-8137.2004.01285.x","article-title":"Legume nodule senescence: roles for redox and hormone signalling in the orchestration of the natural aging process","volume":"165","author":"Puppo","year":"2005","journal-title":"New Phytologist"},{"key":"2024052005521323900_CIT0057","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1094\/MPMI-20-3-0262","article-title":"Characterization of genomic clones and expression analysis of the three types of superoxide dismutases during nodule development in Lotus japonicus","volume":"20","author":"Rubio","year":"2007","journal-title":"Molecular Plant-Microbe Interactions"},{"key":"2024052005521323900_CIT0058","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/tpj.14422","article-title":"Phytoglobins in the chloroplasts, nuclei and cytoplasm modulate nitric oxide and interact with abscisic acid","volume":"100","author":"Rubio","year":"2019","journal-title":"The Plant Journal"},{"key":"2024052005521323900_CIT0059","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/tpj.12762","article-title":"Leghemoglobin is nitrated in functional legume nodules in a tyrosine residue within the heme cavity by a nitrite\/peroxide-dependent mechanism","volume":"81","author":"Sainz","year":"2015","journal-title":"The Plant Journal"},{"key":"2024052005521323900_CIT0060","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.molp.2019.01.003","article-title":"MapMan4: a refined protein classification and annotation framework applicable to multi-omics data analysis","volume":"12","author":"Schwacke","year":"2019","journal-title":"Molecular Plant"},{"key":"2024052005521323900_CIT0061","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1007\/s11738-011-0746-4","article-title":"Effects of exogenous hydrogen sulfide on the ascorbate and glutathione metabolism in wheat seedlings leaves under water stress","volume":"33","author":"Shan","year":"2011","journal-title":"Acta Physiologiae Plantarum"},{"key":"2024052005521323900_CIT0062","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jplph.2015.03.015","article-title":"Hydrogen sulfide alleviates toxic effects of arsenate in pea seedlings through up-regulation of the ascorbate\u2013glutathione cycle: Possible involvement of nitric oxide","volume":"181","author":"Singh","year":"2015","journal-title":"Journal of Plant Physiology"},{"key":"2024052005521323900_CIT0063","doi-asserted-by":"crossref","first-page":"W122","DOI":"10.1093\/nar\/gkx382","article-title":"agriGO v20: a GO analysis toolkit for the agricultural community","volume":"45","author":"Tian","year":"2017","journal-title":"Nucleic Acids Research"},{"key":"2024052005521323900_CIT0064","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1146\/annurev-arplant-050312-120235","article-title":"Transport and metabolism in legume-rhizobia symbioses","volume":"64","author":"Udvardi","year":"2013","journal-title":"Annual Review of Plant Biology"},{"key":"2024052005521323900_CIT0065","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.1093\/jxb\/ery184","article-title":"Specificity in nitric oxide signaling","volume":"69","author":"Umbreen","year":"2018","journal-title":"Journal of Experimental Botany"},{"key":"2024052005521323900_CIT0066","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.plaphy.2014.08.019","article-title":"Evaluation of the anti-nitrative effect of plant antioxidants using a cowpea Fe-superoxide dismutase as a target","volume":"83","author":"Urarte","year":"2014","journal-title":"Plant Physiology and Biochemistry"},{"key":"2024052005521323900_CIT0067","doi-asserted-by":"crossref","first-page":"600336","DOI":"10.3389\/fpls.2020.600336","article-title":"A plant gene encoding one-heme and two-heme hemoglobins with extreme reactivities toward diatomic gases and nitrite","volume":"11","author":"Villar","year":"2018","journal-title":"Frontiers in Plant Science"},{"key":"2024052005521323900_CIT0068","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1146\/annurev-arplant-042817-040322","article-title":"Reactive oxygen species in plant signaling","volume":"69","author":"Waszczak","year":"2018","journal-title":"Annual Review of Plant Biology"},{"key":"2024052005521323900_CIT0069","doi-asserted-by":"crossref","first-page":"e105018","DOI":"10.1371\/journal.pone.0105018","article-title":"iNitro-Tyr: prediction of nitrotyrosine sites in proteins with general pseudo amino acid composition","volume":"9","author":"Xu","year":"2014","journal-title":"PLoS One"},{"key":"2024052005521323900_CIT0070","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1093\/bioinformatics\/btq249","article-title":"PSORTb 30: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes","volume":"26","author":"Yu","year":"2010","journal-title":"Bioinformatics"},{"key":"2024052005521323900_CIT0071","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/anie.201305876","article-title":"Detection of protein S-sulfhydration by a tag-switch technique","volume":"53","author":"Zhang","year":"2014","journal-title":"Angewandte Chemie International Edition"},{"key":"2024052005521323900_CIT0072","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.cmet.2019.10.007","article-title":"Selective persulfide detection reveals evolutionarily conserved antiaging effects of S-sulfhydration","volume":"30","author":"Zivanovic","year":"2019","journal-title":"Cell Metabolism"},{"key":"2024052005521323900_CIT0073","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s11104-020-04465-9","article-title":"Hydrogen sulfide is a crucial element of the antioxidant defense system in Glycine max\u2013Sinorhizobium fredii symbiotic root nodules","volume":"449","author":"Zou","year":"2020","journal-title":"Plant and Soil"},{"key":"2024052005521323900_CIT0074","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1094\/MPMI-01-19-0003-R","article-title":"Hydrogen sulfide promotes nodulation and nitrogen fixation in soybean\u2013rhizobia symbiotic system","volume":"32","author":"Zou","year":"2019","journal-title":"Molecular Plant-Microbe Interactions"}],"container-title":["Journal of Experimental Botany"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jxb\/advance-article-pdf\/doi\/10.1093\/jxb\/erad436\/54804147\/erad436.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jxb\/article-pdf\/75\/10\/3009\/57674281\/erad436.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jxb\/article-pdf\/75\/10\/3009\/57674281\/erad436.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T05:54:29Z","timestamp":1716184469000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jxb\/article\/75\/10\/3009\/7408765"}},"subtitle":[],"editor":[{"given":"Miriam","family":"Gifford","sequence":"additional","affiliation":[{"name":"University of Warwick , UK"}],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,11,11]]},"references-count":74,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,11,11]]},"published-print":{"date-parts":[[2024,5,20]]}},"URL":"https:\/\/doi.org\/10.1093\/jxb\/erad436","relation":{},"ISSN":["0022-0957","1460-2431"],"issn-type":[{"value":"0022-0957","type":"print"},{"value":"1460-2431","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,5,20]]},"published":{"date-parts":[[2023,11,11]]}}}