{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:05:34Z","timestamp":1789578334468,"version":"build-2803163510"},"reference-count":0,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Drought coordinates hormonal, transcriptional, and metabolic reprogramming, but how abscisic acid (ABA) and 1-aminocyclopropane-1-carboxylic acid (ACC) jointly shape cereal dehydration responses remains unclear. We integrated hormone profiling, transcriptome and promoter analyses, synthetic promoter assays, and metabolite profiling in rice. ABA and ACC contents increased markedly in rice shoots under moderate soil water deficit. Combined ABA + ACC treatment showed larger absolute overlaps with dehydration-responsive genes than either ABA or ACC treatment alone in shoots; in roots, this pattern was observed for induced but not repressed genes. Promoters of dehydration- and ABA-inducible genes were enriched in ACGT-core motifs, including a CGTACG core preferentially embedded in ACGTACGT, designated the eXtended ACGT box (Xbox). Multimerised Xbox conferred transcriptional induction under soil water deficit and in response to ABA. OsICL was induced under soil water deficit and by ABA or ACC; in shoots, combined ABA + ACC treatment produced the highest mean transcript accumulation. OsICL overexpression and knockout lines showed altered organic-acid, sugar, and amino-acid profiles, particularly under soil water deficit, but several metabolites changed in the same direction in both line classes. These findings support an ABA-centred, ACC-modulated model of dehydration-responsive transcription and associate OsICL regulation with broader, condition-dependent changes in primary metabolism.<\/jats:p>","DOI":"10.1093\/jxb\/erag463","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T11:45:43Z","timestamp":1789213543000},"source":"Crossref","is-referenced-by-count":0,"title":["OsICL-associated metabolic reprogramming during dehydration in rice is regulated by ABA and modulated by ACC and its metabolites"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7725-0380","authenticated-orcid":false,"given":"Kyonoshin","family":"Maruyama","sequence":"first","affiliation":[{"name":"Biological Resources and Post-Harvest Division, Japan International Research Center for Agricultural Sciences , 1-1 Ohwashi, Tsukuba, Ibaraki, 305-8686 ,","place":["Japan"]},{"name":"Institute of Life and Environmental Sciences, University of Tsukuba , 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7230-3332","authenticated-orcid":false,"given":"Takuma","family":"Ishizaki","sequence":"additional","affiliation":[{"name":"Tropical Agriculture Research Front, Japan International Research Center for Agricultural Sciences , 1091-1 Maezato-Kawarabaru, Ishigaki, Okinawa 907\u20130002 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2298-7016","authenticated-orcid":false,"given":"Shingo","family":"Goto","sequence":"additional","affiliation":[{"name":"Fruit Tree and Tea genome Group, Division of Fruit Tree Breeding Research, Institute of Fruit Tree and Tea Science, National Agriculture and Food Research Organization (NARO) , Tsukuba, Ibaraki ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9459-9267","authenticated-orcid":false,"given":"Miho","family":"Kishimoto","sequence":"additional","affiliation":[{"name":"Biological Resources and Post-Harvest Division, Japan International Research Center for Agricultural Sciences , 1-1 Ohwashi, Tsukuba, Ibaraki, 305-8686 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4933-2630","authenticated-orcid":false,"given":"Kyouko","family":"Yoshiwara","sequence":"additional","affiliation":[{"name":"Biological Resources and Post-Harvest Division, Japan International Research Center for Agricultural Sciences , 1-1 Ohwashi, Tsukuba, Ibaraki, 305-8686 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9199-181X","authenticated-orcid":false,"given":"Masaki","family":"Endo","sequence":"additional","affiliation":[{"name":"Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO) , 1-2 Owashi, Tsukuba, Ibaraki, 305-8634 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0052-6155","authenticated-orcid":false,"given":"Miyako","family":"Kusano","sequence":"additional","affiliation":[{"name":"Institute of Life and Environmental Sciences, University of Tsukuba , 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572 ,","place":["Japan"]},{"name":"RIKEN Center for Sustainable Resource Science , Tsurumi, Yokohama 230-0045 ,","place":["Japan"]},{"name":"Tsukuba Plant Innovation Research Center, University of Tsukuba , 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"RIKEN Center for Sustainable Resource Science , Tsurumi, Yokohama 230-0045 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2967-5082","authenticated-orcid":false,"given":"Mikiko","family":"Kojima","sequence":"additional","affiliation":[{"name":"RIKEN Center for Sustainable Resource Science , Tsurumi, Yokohama 230-0045 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4207-297X","authenticated-orcid":false,"given":"Yumiko","family":"Takebayashi","sequence":"additional","affiliation":[{"name":"RIKEN Center for Sustainable Resource Science , Tsurumi, Yokohama 230-0045 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5449-6492","authenticated-orcid":false,"given":"Hitoshi","family":"Sakakibara","sequence":"additional","affiliation":[{"name":"RIKEN Center for Sustainable Resource Science , Tsurumi, Yokohama 230-0045 ,","place":["Japan"]},{"name":"Graduate School of Bioagricultural Sciences, Nagoya University , Nagoya ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2046-8973","authenticated-orcid":false,"given":"Tetsuya","family":"Sakurai","sequence":"additional","affiliation":[{"name":"Faculty of Agriculture and Marine Science, Kochi University , 200 Monobe, Nankoku, Kochi 783-8502 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6019-1732","authenticated-orcid":false,"given":"Shingo","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Biomanufacturing Process Research Center, National Institute of Advanced Industrial Science and Technology (AIST) , Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5689-3678","authenticated-orcid":false,"given":"Nobutaka","family":"Mitsuda","sequence":"additional","affiliation":[{"name":"Biomanufacturing Process Research Center, National Institute of Advanced Industrial Science and Technology (AIST) , Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,16]]},"container-title":["Journal of Experimental 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